AutismKB 2.0

Annotation Detail for MEIS2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:MEIS2 ( HsT18361,MGC2820,MRG1 )
Gene Full Name: Meis homeobox 2
Band: 15q14
Quick LinksEntrez ID:4212; OMIM: 601740; Uniprot ID:MEIS2_HUMAN; ENSEMBL ID: ENSG00000134138; HGNC ID: 7001
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body17 / 70761240
blastocyst0 / 623190 
fetus73 / 564012129
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult99 / 193912151
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma2 / 8282324
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor58 / 263845219
glioma1 / 1068839
head and neck tumor5 / 13630236
kidney tumor4 / 6895958
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia4 / 9725041
normal176 / 336030752
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS6 / 12568047
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain72 / 110098965
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue23 / 215722106
esophagus0 / 202090 
eye12 / 21105456
heart5 / 8962655
intestine5 / 23447221
kidney6 / 21177728
larynx1 / 2414541
liver3 / 20774314
lung19 / 33697456
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth2 / 6705229
muscle2 / 10771518
nerve0 / 157680 
ovary0 / 1020510 
pancreas12 / 21481255
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland4 / 16585241
placenta4 / 28082514
prostate9 / 18934547
salivary gland0 / 201550 
skin3 / 21057414
spleen2 / 5395237
stomach0 / 966190 
testis45 / 330442136
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus21 / 23287890
vascular3 / 5178057
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 207480_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts10.7
Adipocyte19.4
AdrenalCortex54.4
Adrenalgland22.1
Amygdala43.85
Appendix24.3
AtrioventricularNode6.2
BDCA4+_DentriticCells7.05
Bonemarrow7.85
BronchialEpithelialCells8.95
CD105+_Endothelial7.75
CD14+_Monocytes7.75
CD19+_BCells(neg._sel.)7.5
CD33+_Myeloid9.25
CD34+9
CD4+_Tcells7.15
CD56+_NKCells8.7
CD71+_EarlyErythroid7.35
CD8+_Tcells6.75
CardiacMyocytes29
Caudatenucleus236.5
Cerebellum16.6
CerebellumPeduncles9.75
CiliaryGanglion5.9
CingulateCortex8.7
Colorectaladenocarcinoma7.75
DorsalRootGanglion6.2
FetalThyroid7.7
Fetalbrain287.4
Fetalliver7.4
Fetallung14.1
GlobusPallidus6.35
Heart10.9
Hypothalamus24.5
Kidney6.75
Leukemia_chronicMyelogenousK-5627.3
Leukemia_promyelocytic-HL-607.75
Leukemialymphoblastic(MOLT-4)5.75
Liver11
Lung10.7
Lymphnode8.8
Lymphoma_burkitts(Daudi)10.75
Lymphoma_burkitts(Raji)11.65
MedullaOblongata63.65
OccipitalLobe14.2
OlfactoryBulb6.2
Ovary9.75
Pancreas6.4
PancreaticIslet110.8
ParietalLobe8.85
Pituitary64.2
Placenta8.5
Pons32.3
PrefrontalCortex92.1
Prostate173.15
Salivarygland70
SkeletalMuscle9.4
Skin6.5
SmoothMuscle22.45
Spinalcord17.3
SubthalamicNucleus7.7
SuperiorCervicalGanglion9.8
TemporalLobe7.65
Testis6.55
TestisGermCell6.7
TestisIntersitial6.4
TestisLeydigCell8
TestisSeminiferousTubule6.6
Thalamus8.25
Thymus16.25
Thyroid11.9
Tongue8.25
Tonsil7.7
Trachea9.9
TrigeminalGanglion7.95
Uterus521.7
UterusCorpus9.5
WholeBlood8.7
Wholebrain17.25
colon51.85
pineal_day16.96
pineal_night14.76
retina31.4
small_intestine41.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P82200
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala8.06 ± 0.57
Basal Forebrain8.92 ± 0.39
Basal Part of Pons6.31 ± 0.16
Cerebellar Cortex6.68 ± 0.29
Cerebellar Nuclei7.61 ± 0.71
Claustrum7.13 ± 0.46
Epithalamus7.29 ± 0.99
Frontal Lobe7.02 ± 0.47
Globus Pallidus7.54 ± 0.59
Hypothalamus6.72 ± 1.03
Insula6.9 ± 0.4
Limbic Lobe6.77 ± 0.9
Mesencephalon6.82 ± 0.89
Myelencephalon7.41 ± 0.85
Occipital Lobe7.94 ± 1.12
Parietal Lobe7.02 ± 0.57
Pontine Tegmentum7.83 ± 0.54
Striatum9.64 ± 0.85
Subthalamus6.31 ± 0.39
Temporal Lobe6.78 ± 0.4
Thalamus7.27 ± 0.56
White Matter8.33 ± 0.59
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mrg1CBCerebellum4.85
5.99
Mrg1CTXCerebral cortex54.16
44.12
Mrg1HIPHippocampal region20.8
17.76
Mrg1HPFHippocampal formation33.74
31.55
Mrg1HYHypothalamus22.03
23.11
Mrg1LSXLateral septal complex100
99.85
Mrg1MBMidbrain34.87
33.57
Mrg1MYMedulla51.75
60.5
Mrg1OLFOlfactory bulb100
100
Mrg1PPons57
67.71
Mrg1PALPallidum67.4
75.13
Mrg1RHPRetrohippocampal region55.07
50.5
Mrg1sAMYStriatum-like amygdalar nuclei99.1
100
Mrg1STRStriatum100
100
Mrg1STRdStriatum dorsal region100
100
Mrg1STRvStriatum ventral region100
100
Mrg1THThalamus14.69
16.5
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00064349 17 280 296 AWLFQHLTHPYPSEEQK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved