Annotation Detail for MET
Basic Information Top
| Gene Symbol: | MET ( AUTS9,HGFR,RCCP2,c-Met ) |
|---|---|
| Gene Full Name: | met proto-oncogene (hepatocyte growth factor receptor) |
| Band: | 7q31 |
| Quick Links | Entrez ID:4233; OMIM: 164860; Uniprot ID:MET_HUMAN; ENSEMBL ID: ENSG00000105976; HGNC ID: 7029 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.132966
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 1 / 70761 | 14 |  |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 57 / 564012 | 101 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 4 / 55556 | 71 | |
| adult | 109 / 1939121 | 56 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 1 / 17475 | 57 | |
| breast (mammary gland) tumor | 2 / 94178 | 21 | |
| cervical tumor | 2 / 34366 | 58 | |
| chondrosarcoma | 9 / 82823 | 108 | |
| colorectal tumor | 23 / 114246 | 201 |  |
| esophageal tumor | 5 / 17290 | 289 | |
| gastrointestinal tumor | 22 / 119369 | 184 | |
| germ cell tumor | 4 / 263845 | 15 | |
| glioma | 2 / 106883 | 18 | |
| head and neck tumor | 11 / 136302 | 80 | |
| kidney tumor | 3 / 68959 | 43 | |
| leukemia | 1 / 95842 | 10 |  |
| liver tumor | 12 / 96359 | 124 | |
| lung tumor | 9 / 103127 | 87 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 2 / 97250 | 20 | |
| normal | 162 / 3360307 | 48 | |
| ovarian tumor | 3 / 76682 | 39 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 2 / 102680 | 19 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 5 / 124949 | 40 | |
| soft tissue/muscle tissue tumor | 4 / 125191 | 31 | |
| uterine tumor | 6 / 90257 | 66 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 16 / 40015 | 399 | |
| bladder | 1 / 29757 | 33 | |
| blood | 0 / 123478 | 0 | |
| bone | 6 / 71655 | 83 | |
| bone marrow | 3 / 48801 | 61 | |
| brain | 16 / 1100989 | 14 | |
| cervix | 2 / 48171 | 41 | |
| connective tissue | 6 / 149255 | 40 | |
| ear | 3 / 16212 | 185 | |
| embryonic tissue | 1 / 215722 | 4 | |
| esophagus | 5 / 20209 | 247 | |
| eye | 9 / 211054 | 42 | |
| heart | 1 / 89626 | 11 | |
| intestine | 29 / 234472 | 123 | |
| kidney | 23 / 211777 | 108 | |
| larynx | 0 / 24145 | 0 | |
| liver | 14 / 207743 | 67 | |
| lung | 29 / 336974 | 86 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 5 / 91610 | 54 | |
| mammary gland | 6 / 153271 | 39 | |
| mouth | 6 / 67052 | 89 | |
| muscle | 6 / 107715 | 55 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 3 / 102051 | 29 | |
| pancreas | 0 / 214812 | 0 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 11 / 280825 | 39 | |
| prostate | 3 / 189345 | 15 | |
| salivary gland | 2 / 20155 | 99 | |
| skin | 12 / 210574 | 56 | |
| spleen | 1 / 53952 | 18 | |
| stomach | 6 / 96619 | 62 | |
| testis | 3 / 330442 | 9 | |
| thymus | 3 / 81131 | 36 | |
| thyroid | 6 / 47473 | 126 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 12 / 52413 | 228 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 14 / 232878 | 60 | |
| vascular | 4 / 51780 | 77 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 211599_x_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 4.7 | |
| Adipocyte | 3.7 | |
| AdrenalCortex | 3.75 | |
| Adrenalgland | 3.1 | |
| Amygdala | 3.95 | |
| Appendix | 3.65 | |
| AtrioventricularNode | 2.75 | |
| BDCA4+_DentriticCells | 4.1 | |
| Bonemarrow | 3.65 | |
| BronchialEpithelialCells | 5.55 | |
| CD105+_Endothelial | 3.7 | |
| CD14+_Monocytes | 4.05 | |
| CD19+_BCells(neg._sel.) | 4 | |
| CD33+_Myeloid | 4.75 | |
| CD34+ | 4.75 | |
| CD4+_Tcells | 4.1 | |
| CD56+_NKCells | 4.4 | |
| CD71+_EarlyErythroid | 3.45 | |
| CD8+_Tcells | 3.6 | |
| CardiacMyocytes | 4.6 | |
| Caudatenucleus | 3.3 | |
| Cerebellum | 3 | |
| CerebellumPeduncles | 4.15 | |
| CiliaryGanglion | 2.55 | |
| CingulateCortex | 3.75 | |
| Colorectaladenocarcinoma | 3.8 | |
| DorsalRootGanglion | 2.75 | |
| FetalThyroid | 3.6 | |
| Fetalbrain | 3.75 | |
| Fetalliver | 3.15 | |
| Fetallung | 3.15 | |
| GlobusPallidus | 2.7 | |
| Heart | 4.65 | |
| Hypothalamus | 4 | |
| Kidney | 3 | |
| Leukemia_chronicMyelogenousK-562 | 3.35 | |
| Leukemia_promyelocytic-HL-60 | 3.3 | |
| Leukemialymphoblastic(MOLT-4) | 2.95 | |
| Liver | 4.95 | |
| Lung | 4.05 | |
| Lymphnode | 3.25 | |
| Lymphoma_burkitts(Daudi) | 4.7 | |
| Lymphoma_burkitts(Raji) | 5.1 | |
| MedullaOblongata | 3.4 | |
| OccipitalLobe | 3.35 | |
| OlfactoryBulb | 2.95 | |
| Ovary | 2.45 | |
| Pancreas | 2.95 | |
| PancreaticIslet | 3.95 | |
| ParietalLobe | 3.85 | |
| Pituitary | 4.35 | |
| Placenta | 3.9 | |
| Pons | 3.5 | |
| PrefrontalCortex | 4.65 | |
| Prostate | 4.4 | |
| Salivarygland | 2.9 | |
| SkeletalMuscle | 4.3 | |
| Skin | 2.8 | |
| SmoothMuscle | 4.2 | |
| Spinalcord | 3.95 | |
| SubthalamicNucleus | 3.3 | |
| SuperiorCervicalGanglion | 4.1 | |
| TemporalLobe | 3.35 | |
| Testis | 3.2 | |
| TestisGermCell | 3.15 | |
| TestisIntersitial | 3.1 | |
| TestisLeydigCell | 3.65 | |
| TestisSeminiferousTubule | 3.2 | |
| Thalamus | 3.75 | |
| Thymus | 2.95 | |
| Thyroid | 4.8 | |
| Tongue | 3.6 | |
| Tonsil | 3.6 | |
| Trachea | 3.5 | |
| TrigeminalGanglion | 3.65 | |
| Uterus | 3.05 | |
| UterusCorpus | 4 | |
| WholeBlood | 4.1 | |
| Wholebrain | 3.2 | |
| colon | 3.75 | |
| pineal_day | 4.62 | |
| pineal_night | 4.52 | |
| retina | 4.55 | |
| small_intestine | 3.6 | |
- Probe name: A_23_P145846
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 5.29 ± 0.54 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 6.87 ± 1.01 | |
| Basal Part of Pons | 4.94 ± 0.91 | |
| Cerebellar Cortex | 5.14 ± 0.93 | |
| Cerebellar Nuclei | 6.21 ± 0.81 | |
| Claustrum | 4.61 ± 0.95 | |
| Epithalamus | 4.93 ± 0.57 | |
| Frontal Lobe | 4.94 ± 0.92 | |
| Globus Pallidus | 5.78 ± 0.75 | |
| Hypothalamus | 5.2 ± 0.66 | |
| Insula | 5.85 ± 0.82 | |
| Limbic Lobe | 6.45 ± 1.45 | |
| Mesencephalon | 5.65 ± 0.62 | |
| Myelencephalon | 6.06 ± 1.25 | |
| Occipital Lobe | 7.68 ± 0.51 | |
| Parietal Lobe | 6.49 ± 0.81 | |
| Pontine Tegmentum | 6.22 ± 1.15 | |
| Striatum | 4.85 ± 1.39 | |
| Subthalamus | 5.45 ± 1 | |
| Temporal Lobe | 7.1 ± 0.6 | |
| Thalamus | 5.5 ± 0.78 | |
| White Matter | 6.29 ± 0.58 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Met | CB | Cerebellum | 2.56 | |
| 3.08 | | |||
| Met | CTX | Cerebral cortex | 5.6 | |
| 4.7 | | |||
| Met | HIP | Hippocampal region | 1.09 | |
| 1.29 | | |||
| Met | HPF | Hippocampal formation | 1.86 | |
| 1.99 | | |||
| Met | HY | Hypothalamus | 0.43 | |
| 0.67 | | |||
| Met | LSX | Lateral septal complex | 5.25 | |
| 4.73 | | |||
| Met | MB | Midbrain | 0.57 | |
| 0.67 | | |||
| Met | MY | Medulla | 2.74 | |
| 2.81 | | |||
| Met | OLF | Olfactory bulb | 5.89 | |
| 6.88 | | |||
| Met | P | Pons | 3.98 | |
| 5.57 | | |||
| Met | PAL | Pallidum | 0.14 | |
| 0.15 | | |||
| Met | RHP | Retrohippocampal region | 3.08 | |
| 2.68 | | |||
| Met | sAMY | Striatum-like amygdalar nuclei | 2.39 | |
| 2.24 | | |||
| Met | STR | Striatum | 1.03 | |
| 1.04 | | |||
| Met | STRd | Striatum dorsal region | 0.78 | |
| 0.87 | | |||
| Met | STRv | Striatum ventral region | 0.77 | |
| 0.7 | | |||
| Met | TH | Thalamus | 0.72 | |
| 0.88 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00096835 | 22 | 899 | 920 | SCENIHLHSEAVLCTVPNDLLK | Peptide Atlas |