AutismKB 2.0

Annotation Detail for MGST1


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Basic Information Top
Gene Symbol:MGST1 ( GST12,MGC14525,MGST,MGST-I )
Gene Full Name: microsomal glutathione S-transferase 1
Band: 12p12.3
Quick LinksEntrez ID:4257; OMIM: 138330; Uniprot ID:MGST1_HUMAN; ENSEMBL ID: ENSG00000008394; HGNC ID: 7061
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst3 / 6231948
fetus81 / 564012143
neonate1 / 3109732
infant0 / 236200 
juvenile3 / 5555653
adult257 / 1939121132
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor6 / 12794468
bladder carcinoma42 / 174752403
breast (mammary gland) tumor22 / 94178233
cervical tumor0 / 343660 
chondrosarcoma15 / 82823181
colorectal tumor8 / 11424670
esophageal tumor0 / 172900 
gastrointestinal tumor19 / 119369159
germ cell tumor8 / 26384530
glioma11 / 106883102
head and neck tumor24 / 136302176
kidney tumor14 / 68959203
leukemia7 / 9584273
liver tumor11 / 96359114
lung tumor11 / 103127106
lymphoma0 / 717550 
non-neoplasia6 / 9725061
normal360 / 3360307107
ovarian tumor7 / 7668291
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer19 / 102680185
retinoblastoma0 / 463560 
skin tumor19 / 124949152
soft tissue/muscle tissue tumor9 / 12519171
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue4 / 13106305
adrenal gland18 / 33197542
ascites5 / 40015124
bladder44 / 297571478
blood4 / 12347832
bone7 / 7165597
bone marrow8 / 48801163
brain56 / 110098950
cervix0 / 481710 
connective tissue15 / 149255100
ear0 / 162120 
embryonic tissue11 / 21572250
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine22 / 23447293
kidney26 / 211777122
larynx3 / 24145124
liver99 / 207743476
lung56 / 336974166
lymph0 / 442700 
lymph node5 / 9161054
mammary gland52 / 153271339
mouth2 / 6705229
muscle6 / 10771555
nerve1 / 1576863
ovary9 / 10205188
pancreas8 / 21481237
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta6 / 28082521
prostate30 / 189345158
salivary gland3 / 20155148
skin29 / 210574137
spleen0 / 539520 
stomach13 / 96619134
testis25 / 33044275
thymus1 / 8113112
thyroid18 / 47473379
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus23 / 23287898
vascular1 / 5178019
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15962_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7 ± 0.52
Basal Forebrain6.45 ± 0.33
Basal Part of Pons5.51 ± 0.53
Cerebellar Cortex5.86 ± 0.22
Cerebellar Nuclei5.59 ± 0.69
Claustrum6.07 ± 0.76
Epithalamus7.1 ± 0.43
Frontal Lobe6.33 ± 0.46
Globus Pallidus7.82 ± 0.42
Hypothalamus6.6 ± 0.43
Insula6.44 ± 0.3
Limbic Lobe6.23 ± 0.62
Mesencephalon6.72 ± 0.56
Myelencephalon6.43 ± 0.66
Occipital Lobe5.79 ± 0.61
Parietal Lobe6.2 ± 0.64
Pontine Tegmentum6.62 ± 0.4
Striatum7.03 ± 0.37
Subthalamus6.07 ± 0.26
Temporal Lobe6.5 ± 0.48
Thalamus6.7 ± 0.42
White Matter5.08 ± 0.16
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mgst1CBCerebellum0.99
2.02
Mgst1CTXCerebral cortex2.74
3.62
Mgst1HIPHippocampal region2.59
4.43
Mgst1HPFHippocampal formation1.83
2.91
Mgst1HYHypothalamus0.49
0.66
Mgst1LSXLateral septal complex0.32
0.32
Mgst1MBMidbrain0.46
0.93
Mgst1MYMedulla0.45
0.75
Mgst1OLFOlfactory bulb1.45
2.21
Mgst1PPons0.31
0.87
Mgst1PALPallidum0.32
0.31
Mgst1RHPRetrohippocampal region0.14
0.15
Mgst1sAMYStriatum-like amygdalar nuclei1.69
1.75
Mgst1STRStriatum1.55
2.25
Mgst1STRdStriatum dorsal region1.23
2.18
Mgst1STRvStriatum ventral region2.73
2.99
Mgst1THThalamus1.1
1.79
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
MGST1_HUMAN_114 16 114 129 IYHTIAYLTPLPQPNR PRIDE
MGST1_HUMAN_42 13 42 54 VFANPEDCVAFGK PRIDE
PAp00004617 14 42 55 KVFANPEDCVAFGK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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