AutismKB 2.0

Annotation Detail for MGST3


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Basic Information Top
Gene Symbol:MGST3 ( GST-III )
Gene Full Name: microsomal glutathione S-transferase 3
Band: 1q24.1
Quick LinksEntrez ID:4259; OMIM: 604564; Uniprot ID:MGST3_HUMAN; ENSEMBL ID: ENSG00000143198; HGNC ID: 7064
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body5 / 7076170
blastocyst5 / 6231980
fetus112 / 564012198
neonate2 / 3109764
infant2 / 2362084
juvenile1 / 5555617
adult249 / 1939121128
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor5 / 12794390
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor2 / 3436658
chondrosarcoma2 / 8282324
colorectal tumor8 / 11424670
esophageal tumor2 / 17290115
gastrointestinal tumor20 / 119369167
germ cell tumor13 / 26384549
glioma20 / 106883187
head and neck tumor2 / 13630214
kidney tumor5 / 6895972
leukemia5 / 9584252
liver tumor8 / 9635983
lung tumor7 / 10312767
lymphoma0 / 717550 
non-neoplasia9 / 9725092
normal480 / 3360307142
ovarian tumor3 / 7668239
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer6 / 10268058
retinoblastoma1 / 4635621
skin tumor3 / 12494924
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue14 / 131061068
adrenal gland11 / 33197331
ascites5 / 40015124
bladder2 / 2975767
blood5 / 12347840
bone7 / 7165597
bone marrow2 / 4880140
brain116 / 1100989105
cervix2 / 4817141
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue15 / 21572269
esophagus2 / 2020998
eye31 / 211054146
heart36 / 89626401
intestine24 / 234472102
kidney14 / 21177766
larynx0 / 241450 
liver17 / 20774381
lung55 / 336974163
lymph0 / 442700 
lymph node0 / 916100 
mammary gland4 / 15327126
mouth1 / 6705214
muscle17 / 107715157
nerve1 / 1576863
ovary4 / 10205139
pancreas24 / 214812111
parathyroid15 / 20539730
pharynx2 / 4132848
pituitary gland4 / 16585241
placenta61 / 280825217
prostate20 / 189345105
salivary gland0 / 201550 
skin32 / 210574151
spleen2 / 5395237
stomach20 / 96619206
testis22 / 33044266
thymus1 / 8113112
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord2 / 13680146
uterus24 / 232878103
vascular6 / 51780115
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 201403_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts515.15
Adipocyte854.75
AdrenalCortex325.05
Adrenalgland621.6
Amygdala824.95
Appendix355.75
AtrioventricularNode83.45
BDCA4+_DentriticCells183.65
Bonemarrow437.3
BronchialEpithelialCells1295.05
CD105+_Endothelial1182.2
CD14+_Monocytes446.65
CD19+_BCells(neg._sel.)384.3
CD33+_Myeloid608.45
CD34+376.85
CD4+_Tcells178.4
CD56+_NKCells260.15
CD71+_EarlyErythroid4612.5
CD8+_Tcells162.35
CardiacMyocytes453.85
Caudatenucleus468.85
Cerebellum400
CerebellumPeduncles622.3
CiliaryGanglion172.35
CingulateCortex655.85
Colorectaladenocarcinoma279.4
DorsalRootGanglion209.65
FetalThyroid795.05
Fetalbrain578.75
Fetalliver804.8
Fetallung469.45
GlobusPallidus344.75
Heart2807.75
Hypothalamus1401.55
Kidney671.2
Leukemia_chronicMyelogenousK-562236.1
Leukemia_promyelocytic-HL-6041.3
Leukemialymphoblastic(MOLT-4)126.7
Liver345.15
Lung858.25
Lymphnode193.15
Lymphoma_burkitts(Daudi)6.6
Lymphoma_burkitts(Raji)29.85
MedullaOblongata849.35
OccipitalLobe888.7
OlfactoryBulb389.9
Ovary222.8
Pancreas190.15
PancreaticIslet409.65
ParietalLobe728.2
Pituitary575.9
Placenta973.65
Pons457.25
PrefrontalCortex1215.35
Prostate555.3
Salivarygland340.15
SkeletalMuscle393.75
Skin149.9
SmoothMuscle668.45
Spinalcord905.45
SubthalamicNucleus575.15
SuperiorCervicalGanglion88.25
TemporalLobe762.65
Testis563.85
TestisGermCell667.35
TestisIntersitial232.25
TestisLeydigCell337.4
TestisSeminiferousTubule287.25
Thalamus1200.7
Thymus304.2
Thyroid672.2
Tongue334.4
Tonsil66.75
Trachea347.85
TrigeminalGanglion165.05
Uterus333.2
UterusCorpus287.5
WholeBlood223.2
Wholebrain1671.25
colon1195.95
pineal_day1278.62
pineal_night1107.78
retina954.9
small_intestine1526.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16174_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.17 ± 0.43
Basal Forebrain10.2 ± 0.3
Basal Part of Pons11.06 ± 0.27
Cerebellar Cortex10.04 ± 0.26
Cerebellar Nuclei10.87 ± 0.34
Claustrum9.98 ± 0.78
Epithalamus10.18 ± 0.31
Frontal Lobe10.74 ± 0.49
Globus Pallidus10.4 ± 0.77
Hypothalamus10.72 ± 0.55
Insula10.64 ± 0.39
Limbic Lobe10.04 ± 0.82
Mesencephalon10.35 ± 0.66
Myelencephalon10.32 ± 0.68
Occipital Lobe9.73 ± 0.65
Parietal Lobe10.46 ± 0.6
Pontine Tegmentum10.43 ± 0.48
Striatum9.77 ± 0.62
Subthalamus11.42 ± 0.22
Temporal Lobe10.55 ± 0.55
Thalamus10.45 ± 0.45
White Matter9.96 ± 0.28
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mgst3CBCerebellum28.21
44.12
Mgst3CTXCerebral cortex85.31
88.42
Mgst3HIPHippocampal region25.65
38.44
Mgst3HPFHippocampal formation47.49
63.45
Mgst3HYHypothalamus20.38
23.7
Mgst3LSXLateral septal complex15.47
18.26
Mgst3MBMidbrain32.77
44.41
Mgst3MYMedulla48.01
86.67
Mgst3OLFOlfactory bulb65.42
94.58
Mgst3PPons49.63
81.39
Mgst3PALPallidum31.24
43.35
Mgst3RHPRetrohippocampal region78.37
91.92
Mgst3sAMYStriatum-like amygdalar nuclei14.42
17.9
Mgst3STRStriatum11.05
12.78
Mgst3STRdStriatum dorsal region8.13
9.02
Mgst3STRvStriatum ventral region16.69
18.67
Mgst3THThalamus99.39
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
MGST3_HUMAN_114 27 114 140 GALGSIALLGLVGTTVCSAFQHLGWVK PRIDE
MGST3_HUMAN_84 13 84 96 IASGLGLAWIVGR PRIDE
MGST3_HUMAN_98 14 98 111 VLYAYGYYTGEPSK PRIDE
PAp00004410 26 48 73 KKYKVEYPIMYSTDPENGHIFNCIQR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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