AutismKB 2.0

Annotation Detail for MIF


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Basic Information Top
Gene Symbol:MIF ( GIF,GLIF,MMIF )
Gene Full Name: macrophage migration inhibitory factor (glycosylation-inhibiting factor)
Band: 22q11.23
Quick LinksEntrez ID:4282; OMIM: 153620; Uniprot ID:MIF_HUMAN; ENSEMBL ID: ENSG00000133460; HGNC ID: 7097
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst26 / 62319417
fetus110 / 564012195
neonate5 / 31097160
infant3 / 23620127
juvenile5 / 5555689
adult221 / 1939121113
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma1 / 1747557
breast (mammary gland) tumor10 / 94178106
cervical tumor3 / 3436687
chondrosarcoma10 / 82823120
colorectal tumor8 / 11424670
esophageal tumor1 / 1729057
gastrointestinal tumor33 / 119369276
germ cell tumor35 / 263845132
glioma39 / 106883364
head and neck tumor1 / 1363027
kidney tumor6 / 6895987
leukemia20 / 95842208
liver tumor26 / 96359269
lung tumor40 / 103127387
lymphoma22 / 71755306
non-neoplasia4 / 9725041
normal512 / 3360307152
ovarian tumor11 / 76682143
pancreatic tumor47 / 104616449
primitive neuroectodermal tumor of the CNS30 / 125680238
prostate cancer16 / 102680155
retinoblastoma3 / 4635664
skin tumor61 / 124949488
soft tissue/muscle tissue tumor22 / 125191175
uterine tumor16 / 90257177
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland7 / 33197210
ascites25 / 40015624
bladder0 / 297570 
blood11 / 12347889
bone7 / 7165597
bone marrow4 / 4880181
brain130 / 1100989118
cervix3 / 4817162
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue84 / 215722389
esophagus1 / 2020949
eye45 / 211054213
heart21 / 89626234
intestine28 / 234472119
kidney26 / 211777122
larynx0 / 241450 
liver34 / 207743163
lung92 / 336974273
lymph22 / 44270496
lymph node14 / 91610152
mammary gland14 / 15327191
mouth0 / 670520 
muscle8 / 10771574
nerve1 / 1576863
ovary15 / 102051146
pancreas64 / 214812297
parathyroid7 / 20539340
pharynx0 / 413280 
pituitary gland4 / 16585241
placenta37 / 280825131
prostate25 / 189345132
salivary gland2 / 2015599
skin70 / 210574332
spleen3 / 5395255
stomach8 / 9661982
testis17 / 33044251
thymus4 / 8113149
thyroid0 / 474730 
tonsil4 / 16999235
trachea0 / 524130 
umbilical cord5 / 13680365
uterus39 / 232878167
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 217871_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts3538.1
Adipocyte474.9
AdrenalCortex593.15
Adrenalgland1267
Amygdala1502.55
Appendix148.75
AtrioventricularNode71.4
BDCA4+_DentriticCells665.35
Bonemarrow338.1
BronchialEpithelialCells2519.55
CD105+_Endothelial310.35
CD14+_Monocytes163.25
CD19+_BCells(neg._sel.)693.2
CD33+_Myeloid112.9
CD34+1385.05
CD4+_Tcells613.05
CD56+_NKCells424.5
CD71+_EarlyErythroid15.2
CD8+_Tcells577.55
CardiacMyocytes1770.15
Caudatenucleus504.55
Cerebellum492.25
CerebellumPeduncles905.55
CiliaryGanglion72.35
CingulateCortex600.15
Colorectaladenocarcinoma1350.75
DorsalRootGanglion154.55
FetalThyroid870.1
Fetalbrain543.65
Fetalliver370.65
Fetallung969.95
GlobusPallidus249.35
Heart1845.75
Hypothalamus953.2
Kidney1294.85
Leukemia_chronicMyelogenousK-562517.25
Leukemia_promyelocytic-HL-601951.65
Leukemialymphoblastic(MOLT-4)1775.9
Liver1295.75
Lung2400.75
Lymphnode400.1
Lymphoma_burkitts(Daudi)3081.5
Lymphoma_burkitts(Raji)4677.65
MedullaOblongata576
OccipitalLobe664.55
OlfactoryBulb316.35
Ovary433.3
Pancreas581.1
PancreaticIslet1065.25
ParietalLobe752.4
Pituitary914.5
Placenta1636.2
Pons338.3
PrefrontalCortex1196.3
Prostate4715.15
Salivarygland151.05
SkeletalMuscle15.15
Skin194.15
SmoothMuscle2550.2
Spinalcord844.3
SubthalamicNucleus413.15
SuperiorCervicalGanglion37.25
TemporalLobe862.8
Testis527
TestisGermCell482.75
TestisIntersitial188.7
TestisLeydigCell364.6
TestisSeminiferousTubule293.4
Thalamus844.6
Thymus1168.1
Thyroid2700.05
Tongue714.55
Tonsil616.05
Trachea231.35
TrigeminalGanglion77.6
Uterus615.05
UterusCorpus666.9
WholeBlood337.85
Wholebrain2247.35
colon838.35
pineal_day736.08
pineal_night805.82
retina977.325
small_intestine750.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P49334
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.86 ± 0.69
Basal Forebrain6.98 ± 0.24
Basal Part of Pons7.34 ± 0.54
Cerebellar Cortex7.08 ± 0.49
Cerebellar Nuclei6.9 ± 0.45
Claustrum6.42 ± 0.91
Epithalamus6.99 ± 0.38
Frontal Lobe7.26 ± 0.5
Globus Pallidus6.57 ± 0.47
Hypothalamus7.5 ± 0.32
Insula7.47 ± 0.41
Limbic Lobe6.97 ± 0.79
Mesencephalon6.8 ± 0.57
Myelencephalon6.96 ± 0.67
Occipital Lobe6.31 ± 0.7
Parietal Lobe6.9 ± 0.58
Pontine Tegmentum6.96 ± 0.58
Striatum6.55 ± 0.71
Subthalamus6.66 ± 0.74
Temporal Lobe7.26 ± 0.55
Thalamus6.9 ± 0.51
White Matter6.36 ± 0.47
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
MifCBCerebellum24.91
34.44
MifCTXCerebral cortex33.75
20.85
MifHIPHippocampal region48.83
31.28
MifHPFHippocampal formation49.24
32.11
MifHYHypothalamus19.53
12.61
MifLSXLateral septal complex10.44
5.49
MifMBMidbrain22.74
18.29
MifMYMedulla30.11
27.59
MifOLFOlfactory bulb45.03
30.67
MifPPons26.45
23.5
MifPALPallidum17.81
16
MifRHPRetrohippocampal region50.29
32.85
MifsAMYStriatum-like amygdalar nuclei17.99
11.74
MifSTRStriatum6.63
4.51
MifSTRdStriatum dorsal region3.67
2.8
MifSTRvStriatum ventral region8.19
5.01
MifTHThalamus18.33
10.86
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
MIF_HUMAN_0 0 0 0 LLCGLLAER PRIDE
MIF_HUMAN_0 0 0 0 MPMFIVNTNVPR PRIDE
MIF_HUMAN_1 11 1 11 PMFIVNTNVPR PRIDE
MIF_HUMAN_1 12 1 12 MPMFIVNTNVPR PRIDE
MIF_HUMAN_2 10 2 11 MFIVNTNVPR PRIDE
MIF_HUMAN_2 11 2 12 PMFIVNTNVPR PRIDE
MIF_HUMAN_3 9 3 11 FIVNTNVPR PRIDE
MIF_HUMAN_4 8 4 11 IVNTNVPR PRIDE
MIF_HUMAN_60 14 60 73 SLHSIGKIGGAQNR PRIDE
MIF_HUMAN_63 11 63 73 SIGKIGGAQNR PRIDE
MIF_HUMAN_68 7 68 74 IGGAQNR PRIDE
MIF_HUMAN_74 13 74 86 SYSKLLCGLLAER PRIDE
MIF_HUMAN_75 13 75 87 SYSKLLCGLLAER PRIDE
MIF_HUMAN_76 11 76 86 SKLLCGLLAER PRIDE
MIF_HUMAN_78 9 78 86 LLCGLLAER PRIDE
MIF_HUMAN_79 9 79 87 LLCGLLAER PRIDE
PAp00000511 10 58 67 ALCSLHSIGK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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