AutismKB 2.0

Annotation Detail for MLLT1


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Basic Information Top
Gene Symbol:MLLT1 ( ENL,LTG19,YEATS1 )
Gene Full Name: myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
Band: 19p13.3
Quick LinksEntrez ID:4298; OMIM: 159556; Uniprot ID:ENL_HUMAN; ENSEMBL ID: ENSG00000130382; HGNC ID: 7134
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst7 / 62319112
fetus30 / 56401253
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult93 / 193912147
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor0 / 343660 
chondrosarcoma5 / 8282360
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor15 / 119369125
germ cell tumor12 / 26384545
glioma10 / 10688393
head and neck tumor10 / 13630273
kidney tumor0 / 689590 
leukemia3 / 9584231
liver tumor1 / 9635910
lung tumor7 / 10312767
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal136 / 336030740
ovarian tumor1 / 7668213
pancreatic tumor10 / 10461695
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer6 / 10268058
retinoblastoma2 / 4635643
skin tumor9 / 12494972
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites1 / 4001524
bladder3 / 29757100
blood3 / 12347824
bone4 / 7165555
bone marrow0 / 488010 
brain20 / 110098918
cervix0 / 481710 
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue18 / 21572283
esophagus0 / 202090 
eye14 / 21105466
heart5 / 8962655
intestine7 / 23447229
kidney0 / 2117770 
larynx2 / 2414582
liver1 / 2077434
lung21 / 33697462
lymph0 / 442700 
lymph node13 / 91610141
mammary gland8 / 15327152
mouth1 / 6705214
muscle3 / 10771527
nerve1 / 1576863
ovary4 / 10205139
pancreas11 / 21481251
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta32 / 280825113
prostate8 / 18934542
salivary gland6 / 20155297
skin13 / 21057461
spleen3 / 5395255
stomach8 / 9661982
testis10 / 33044230
thymus3 / 8113136
thyroid3 / 4747363
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus6 / 23287825
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 214477_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.2
Adipocyte4.15
AdrenalCortex4.65
Adrenalgland3.65
Amygdala4.4
Appendix4.35
AtrioventricularNode3.4
BDCA4+_DentriticCells4.65
Bonemarrow4.3
BronchialEpithelialCells4.15
CD105+_Endothelial4.3
CD14+_Monocytes4.7
CD19+_BCells(neg._sel.)4.5
CD33+_Myeloid5.4
CD34+5.35
CD4+_Tcells4.55
CD56+_NKCells5
CD71+_EarlyErythroid4.1
CD8+_Tcells4.05
CardiacMyocytes5.8
Caudatenucleus3.85
Cerebellum3.45
CerebellumPeduncles4.9
CiliaryGanglion3.1
CingulateCortex4.4
Colorectaladenocarcinoma4.3
DorsalRootGanglion3.4
FetalThyroid4.5
Fetalbrain4.2
Fetalliver3.75
Fetallung3.45
GlobusPallidus3.15
Heart5.7
Hypothalamus4.55
Kidney3.55
Leukemia_chronicMyelogenousK-5623.85
Leukemia_promyelocytic-HL-603.75
Leukemialymphoblastic(MOLT-4)3.35
Liver5.8
Lung4.6
Lymphnode3.6
Lymphoma_burkitts(Daudi)5.5
Lymphoma_burkitts(Raji)6.15
MedullaOblongata3.85
OccipitalLobe3.8
OlfactoryBulb3.35
Ovary2.9
Pancreas3.45
PancreaticIslet4.55
ParietalLobe4.6
Pituitary4.95
Placenta4.4
Pons4.1
PrefrontalCortex5.25
Prostate4.95
Salivarygland3.45
SkeletalMuscle5.15
Skin3.4
SmoothMuscle4.85
Spinalcord4.55
SubthalamicNucleus3.95
SuperiorCervicalGanglion5
TemporalLobe3.9
Testis3.6
TestisGermCell3.5
TestisIntersitial3.6
TestisLeydigCell4.2
TestisSeminiferousTubule3.6
Thalamus4.35
Thymus3.3
Thyroid5.3
Tongue4.25
Tonsil4.15
Trachea3.55
TrigeminalGanglion4.4
Uterus3.45
UterusCorpus3.9
WholeBlood4.6
Wholebrain3.55
colon4.25
pineal_day5.26
pineal_night5.18
retina5.125
small_intestine4.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P418126
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.18 ± 0.41
Basal Forebrain5.02 ± 0.4
Basal Part of Pons5.01 ± 0.52
Cerebellar Cortex4.89 ± 0.4
Cerebellar Nuclei4.91 ± 0.59
Claustrum5.35 ± 0.73
Epithalamus4.72 ± 0.44
Frontal Lobe4.89 ± 0.5
Globus Pallidus4.99 ± 0.47
Hypothalamus4.85 ± 0.51
Insula4.85 ± 0.48
Limbic Lobe5.15 ± 0.59
Mesencephalon4.88 ± 0.59
Myelencephalon5.07 ± 0.55
Occipital Lobe5.09 ± 0.63
Parietal Lobe4.96 ± 0.44
Pontine Tegmentum4.83 ± 0.48
Striatum5.15 ± 0.56
Subthalamus5.24 ± 0.28
Temporal Lobe4.98 ± 0.46
Thalamus5.09 ± 0.55
White Matter4.9 ± 0.47
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mllt1LSXLateral septal complex42.02
28.88
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
ENL_HUMAN_1 10 1 10 MDNQCTVQVR PRIDE
PAp00010272 13 38 50 GPEQCDIQHFVEK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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