Annotation Detail for ACHE
Basic Information Top
| Gene Symbol: | ACHE ( ARACHE,N-ACHE,YT ) |
|---|---|
| Gene Full Name: | acetylcholinesterase |
| Band: | 7q22.1 |
| Quick Links | Entrez ID:43; OMIM: 100740; Uniprot ID:ACES_HUMAN; ENSEMBL ID: ENSG00000087085; HGNC ID: 108 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.154495
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 1 / 70761 | 14 |  |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 27 / 564012 | 47 | |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 3 / 55556 | 53 |  |
| adult | 46 / 1939121 | 23 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 0 / 119369 | 0 | |
| germ cell tumor | 16 / 263845 | 60 | |
| glioma | 3 / 106883 | 28 | |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 4 / 68959 | 58 | |
| leukemia | 2 / 95842 | 20 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 2 / 97250 | 20 | |
| normal | 136 / 3360307 | 40 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 2 / 104616 | 19 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 1 / 46356 | 21 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 1 / 33197 | 30 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 0 / 29757 | 0 | |
| blood | 2 / 123478 | 16 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 87 / 1100989 | 79 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 0 / 149255 | 0 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 6 / 215722 | 27 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 13 / 211054 | 61 | |
| heart | 5 / 89626 | 55 | |
| intestine | 3 / 234472 | 12 | |
| kidney | 8 / 211777 | 37 | |
| larynx | 0 / 24145 | 0 | |
| liver | 1 / 207743 | 4 |  |
| lung | 4 / 336974 | 11 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 0 / 153271 | 0 | |
| mouth | 3 / 67052 | 44 | |
| muscle | 3 / 107715 | 27 | |
| nerve | 3 / 15768 | 190 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 7 / 214812 | 32 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 2 / 280825 | 7 | |
| prostate | 1 / 189345 | 5 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 1 / 53952 | 18 | |
| stomach | 0 / 96619 | 0 | |
| testis | 1 / 330442 | 3 | |
| thymus | 3 / 81131 | 36 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 0 / 232878 | 0 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 205378_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 6 | |
| Adipocyte | 22.3 | |
| AdrenalCortex | 5.8 | |
| Adrenalgland | 4.3 | |
| Amygdala | 5.45 | |
| Appendix | 5.15 | |
| AtrioventricularNode | 4.15 | |
| BDCA4+_DentriticCells | 5.6 | |
| Bonemarrow | 5 | |
| BronchialEpithelialCells | 4.8 | |
| CD105+_Endothelial | 5.55 | |
| CD14+_Monocytes | 5.5 | |
| CD19+_BCells(neg._sel.) | 5.25 | |
| CD33+_Myeloid | 6.2 | |
| CD34+ | 6.4 | |
| CD4+_Tcells | 5.3 | |
| CD56+_NKCells | 6.05 | |
| CD71+_EarlyErythroid | 13.05 | |
| CD8+_Tcells | 4.6 | |
| CardiacMyocytes | 7.05 | |
| Caudatenucleus | 5.55 | |
| Cerebellum | 4.2 | |
| CerebellumPeduncles | 8.85 | |
| CiliaryGanglion | 3.95 | |
| CingulateCortex | 5.25 | |
| Colorectaladenocarcinoma | 5 | |
| DorsalRootGanglion | 4.25 | |
| FetalThyroid | 5 | |
| Fetalbrain | 5.3 | |
| Fetalliver | 4.4 | |
| Fetallung | 4.05 | |
| GlobusPallidus | 3.85 | |
| Heart | 7.15 | |
| Hypothalamus | 27.5 | |
| Kidney | 4.25 | |
| Leukemia_chronicMyelogenousK-562 | 4.5 | |
| Leukemia_promyelocytic-HL-60 | 4.45 | |
| Leukemialymphoblastic(MOLT-4) | 4.05 | |
| Liver | 6.95 | |
| Lung | 5.4 | |
| Lymphnode | 4.3 | |
| Lymphoma_burkitts(Daudi) | 6.5 | |
| Lymphoma_burkitts(Raji) | 7.35 | |
| MedullaOblongata | 4.7 | |
| OccipitalLobe | 4.5 | |
| OlfactoryBulb | 3.95 | |
| Ovary | 3.4 | |
| Pancreas | 4.1 | |
| PancreaticIslet | 5.4 | |
| ParietalLobe | 5.45 | |
| Pituitary | 6 | |
| Placenta | 4.95 | |
| Pons | 4.95 | |
| PrefrontalCortex | 7.25 | |
| Prostate | 5.7 | |
| Salivarygland | 4.1 | |
| SkeletalMuscle | 7.1 | |
| Skin | 3.95 | |
| SmoothMuscle | 5.6 | |
| Spinalcord | 6.95 | |
| SubthalamicNucleus | 4.85 | |
| SuperiorCervicalGanglion | 6.15 | |
| TemporalLobe | 4.8 | |
| Testis | 4.25 | |
| TestisGermCell | 4.05 | |
| TestisIntersitial | 4.2 | |
| TestisLeydigCell | 5.1 | |
| TestisSeminiferousTubule | 4.25 | |
| Thalamus | 7.85 | |
| Thymus | 3.8 | |
| Thyroid | 6 | |
| Tongue | 5.35 | |
| Tonsil | 5 | |
| Trachea | 4.15 | |
| TrigeminalGanglion | 5.2 | |
| Uterus | 3.95 | |
| UterusCorpus | 4.75 | |
| WholeBlood | 5.45 | |
| Wholebrain | 4.8 | |
| colon | 5 | |
| pineal_day | 48.76 | |
| pineal_night | 69.1 | |
| retina | 6.275 | |
| small_intestine | 4.75 | |
- Probe name: A_24_P60845
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 6.11 ± 0.36 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 6.72 ± 0.37 | |
| Basal Part of Pons | 6.54 ± 0.25 | |
| Cerebellar Cortex | 6.36 ± 0.39 | |
| Cerebellar Nuclei | 6.77 ± 0.41 | |
| Claustrum | 6.44 ± 0.5 | |
| Epithalamus | 5.8 ± 0.72 | |
| Frontal Lobe | 6.15 ± 0.39 | |
| Globus Pallidus | 6.62 ± 0.28 | |
| Hypothalamus | 6.93 ± 0.21 | |
| Insula | 5.83 ± 0.37 | |
| Limbic Lobe | 5.99 ± 0.48 | |
| Mesencephalon | 6.4 ± 0.52 | |
| Myelencephalon | 6.24 ± 0.46 | |
| Occipital Lobe | 5.99 ± 0.4 | |
| Parietal Lobe | 6.15 ± 0.51 | |
| Pontine Tegmentum | 6.11 ± 0.38 | |
| Striatum | 6.73 ± 0.54 | |
| Subthalamus | 6.67 ± 0.16 | |
| Temporal Lobe | 5.98 ± 0.4 | |
| Thalamus | 6.17 ± 0.41 | |
| White Matter | 4.89 ± 0.51 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Ache | CB | Cerebellum | 40.31 | |
| 72.04 | | |||
| Ache | CTX | Cerebral cortex | 77.23 | |
| 72.15 | | |||
| Ache | HIP | Hippocampal region | 45.52 | |
| 80.38 | | |||
| Ache | HPF | Hippocampal formation | 60.56 | |
| 81.88 | | |||
| Ache | HY | Hypothalamus | 100 | |
| 100 | | |||
| Ache | LSX | Lateral septal complex | 89.5 | |
| 84.3 | | |||
| Ache | MB | Midbrain | 100 | |
| 100 | | |||
| Ache | MY | Medulla | 100 | |
| 100 | | |||
| Ache | OLF | Olfactory bulb | 65.57 | |
| 70.69 | | |||
| Ache | P | Pons | 100 | |
| 100 | | |||
| Ache | PAL | Pallidum | 97.44 | |
| 100 | | |||
| Ache | RHP | Retrohippocampal region | 81.76 | |
| 83.11 | | |||
| Ache | sAMY | Striatum-like amygdalar nuclei | 99.88 | |
| 100 | | |||
| Ache | STR | Striatum | 53.22 | |
| 62.04 | | |||
| Ache | STRd | Striatum dorsal region | 34.24 | |
| 41.5 | | |||
| Ache | STRv | Striatum ventral region | 59.59 | |
| 67.6 | | |||
| Ache | TH | Thalamus | 90.85 | |
| 99.83 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00033368 | 22 | 427 | 448 | EALSDVVGDHNVVCPVAQLAGR | Peptide Atlas |