AutismKB 2.0

Annotation Detail for MNT


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Basic Information Top
Gene Symbol:MNT ( MAD6,MXD6,ROX,bHLHd3 )
Gene Full Name: MAX binding protein
Band: 17p13.3
Quick LinksEntrez ID:4335; OMIM: 603039; Uniprot ID:MNT_HUMAN; ENSEMBL ID: ENSG00000070444; HGNC ID: 7188
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst2 / 6231932
fetus11 / 56401219
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult59 / 193912130
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma2 / 8282324
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor4 / 11936933
germ cell tumor16 / 26384560
glioma2 / 10688318
head and neck tumor8 / 13630258
kidney tumor2 / 6895929
leukemia3 / 9584231
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma5 / 7175569
non-neoplasia0 / 972500 
normal93 / 336030727
ovarian tumor5 / 7668265
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer8 / 10268077
retinoblastoma1 / 4635621
skin tumor2 / 12494916
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood4 / 12347832
bone2 / 7165527
bone marrow1 / 4880120
brain36 / 110098932
cervix1 / 4817120
connective tissue4 / 14925526
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye7 / 21105433
heart0 / 896260 
intestine6 / 23447225
kidney5 / 21177723
larynx1 / 2414541
liver0 / 2077430 
lung12 / 33697435
lymph1 / 4427022
lymph node3 / 9161032
mammary gland5 / 15327132
mouth6 / 6705289
muscle0 / 1077150 
nerve1 / 1576863
ovary6 / 10205158
pancreas11 / 21481251
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta6 / 28082521
prostate11 / 18934558
salivary gland0 / 201550 
skin8 / 21057437
spleen1 / 5395218
stomach6 / 9661962
testis7 / 33044221
thymus3 / 8113136
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus6 / 23287825
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204206_at
Cell line Expression level Expression bar
721_B_lymphoblasts56.3
Adipocyte48.2
AdrenalCortex50.3
Adrenalgland43.1
Amygdala230.05
Appendix40.25
AtrioventricularNode34.1
BDCA4+_DentriticCells88.5
Bonemarrow44.6
BronchialEpithelialCells18.45
CD105+_Endothelial48.3
CD14+_Monocytes181.55
CD19+_BCells(neg._sel.)84.15
CD33+_Myeloid214.1
CD34+74.05
CD4+_Tcells67.75
CD56+_NKCells81.95
CD71+_EarlyErythroid31.7
CD8+_Tcells65.2
CardiacMyocytes41.85
Caudatenucleus44.15
Cerebellum45.9
CerebellumPeduncles59.65
CiliaryGanglion33.9
CingulateCortex60.85
Colorectaladenocarcinoma46.4
DorsalRootGanglion34.4
FetalThyroid42.75
Fetalbrain163.6
Fetalliver35.15
Fetallung38.2
GlobusPallidus42.8
Heart63.4
Hypothalamus97.1
Kidney30.2
Leukemia_chronicMyelogenousK-56251.7
Leukemia_promyelocytic-HL-6055.8
Leukemialymphoblastic(MOLT-4)33.5
Liver65.8
Lung140.65
Lymphnode36.6
Lymphoma_burkitts(Daudi)57.15
Lymphoma_burkitts(Raji)68.25
MedullaOblongata38.8
OccipitalLobe54.3
OlfactoryBulb39.1
Ovary31.8
Pancreas32.7
PancreaticIslet40.75
ParietalLobe51.35
Pituitary70.95
Placenta79.6
Pons43.35
PrefrontalCortex200
Prostate128.25
Salivarygland32.3
SkeletalMuscle50.7
Skin34.35
SmoothMuscle54.85
Spinalcord81.2
SubthalamicNucleus39.5
SuperiorCervicalGanglion47.45
TemporalLobe37.65
Testis42.8
TestisGermCell52.1
TestisIntersitial39.05
TestisLeydigCell36.8
TestisSeminiferousTubule47.2
Thalamus54.6
Thymus40.95
Thyroid62.85
Tongue44.3
Tonsil44.15
Trachea33.4
TrigeminalGanglion39.35
Uterus79.8
UterusCorpus40
WholeBlood127.35
Wholebrain108.3
colon92
pineal_day123.24
pineal_night141.24
retina82.3
small_intestine46.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13752_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.73 ± 0.95
Basal Forebrain1.93 ± 0.65
Basal Part of Pons2.42 ± 0.9
Cerebellar Cortex2.05 ± 0.71
Cerebellar Nuclei2.4 ± 0.61
Claustrum3.19 ± 0.96
Epithalamus2.03 ± 0.71
Frontal Lobe2.19 ± 0.83
Globus Pallidus2.68 ± 0.66
Hypothalamus2.19 ± 0.77
Insula2.11 ± 1.03
Limbic Lobe2.67 ± 0.82
Mesencephalon2.46 ± 0.84
Myelencephalon2.39 ± 0.8
Occipital Lobe2.76 ± 0.98
Parietal Lobe2.64 ± 0.9
Pontine Tegmentum2.48 ± 0.8
Striatum2.45 ± 0.87
Subthalamus2.08 ± 0.65
Temporal Lobe2.41 ± 0.88
Thalamus2.28 ± 0.79
White Matter2.15 ± 1.12
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
MntCBCerebellum51.51
68.4
MntCTXCerebral cortex52.14
41.92
MntHIPHippocampal region38.35
47.49
MntHPFHippocampal formation38.65
39.69
MntHYHypothalamus22.37
17.09
MntLSXLateral septal complex34.31
25.49
MntMBMidbrain17.89
15.94
MntMYMedulla29.84
30.7
MntOLFOlfactory bulb57.19
51.61
MntPPons17.39
17.39
MntPALPallidum22.92
21.73
MntRHPRetrohippocampal region39.54
30.1
MntsAMYStriatum-like amygdalar nuclei29.88
19.87
MntSTRStriatum17.23
12.36
MntSTRdStriatum dorsal region13.71
10.22
MntSTRvStriatum ventral region14.96
9.86
MntTHThalamus23.21
20.22
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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