AutismKB 2.0

Annotation Detail for MOCS1


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Basic Information Top
Gene Symbol:MOCS1 ( KIAA0381,MIG11,MOCOD )
Gene Full Name: molybdenum cofactor synthesis 1
Band: 6p21.2
Quick LinksEntrez ID:4337; OMIM: 603707; Uniprot ID:MOCS1_HUMAN; ENSEMBL ID: ENSG00000124615; HGNC ID: 7190
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus16 / 56401228
neonate3 / 3109796
infant0 / 236200 
juvenile1 / 5555617
adult76 / 193912139
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor1 / 3436629
chondrosarcoma5 / 8282360
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor8 / 26384530
glioma4 / 10688337
head and neck tumor0 / 1363020 
kidney tumor4 / 6895958
leukemia0 / 958420 
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia10 / 97250102
normal177 / 336030752
ovarian tumor6 / 7668278
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS9 / 12568071
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor5 / 12494940
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone2 / 7165527
bone marrow0 / 488010 
brain66 / 110098959
cervix1 / 4817120
connective tissue10 / 14925566
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye11 / 21105452
heart12 / 89626133
intestine3 / 23447212
kidney14 / 21177766
larynx0 / 241450 
liver3 / 20774314
lung12 / 33697435
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth0 / 670520 
muscle2 / 10771518
nerve2 / 15768126
ovary8 / 10205178
pancreas2 / 2148129
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta25 / 28082589
prostate9 / 18934547
salivary gland0 / 201550 
skin11 / 21057452
spleen2 / 5395237
stomach2 / 9661920
testis10 / 33044230
thymus5 / 8113161
thyroid4 / 4747384
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord0 / 136800 
uterus15 / 23287864
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213181_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.9
Adipocyte10.25
AdrenalCortex12.3
Adrenalgland8.55
Amygdala9.25
Appendix9
AtrioventricularNode6.9
BDCA4+_DentriticCells7.85
Bonemarrow9.35
BronchialEpithelialCells8
CD105+_Endothelial8.4
CD14+_Monocytes8.95
CD19+_BCells(neg._sel.)8.35
CD33+_Myeloid10.25
CD34+9.1
CD4+_Tcells8
CD56+_NKCells8.85
CD71+_EarlyErythroid8.05
CD8+_Tcells6.65
CardiacMyocytes11.7
Caudatenucleus7.85
Cerebellum7.1
CerebellumPeduncles10.55
CiliaryGanglion7.55
CingulateCortex9.05
Colorectaladenocarcinoma8.5
DorsalRootGanglion6.9
FetalThyroid8.5
Fetalbrain8.2
Fetalliver7.75
Fetallung6.6
GlobusPallidus7.15
Heart16
Hypothalamus9.55
Kidney10.4
Leukemia_chronicMyelogenousK-5627.95
Leukemia_promyelocytic-HL-607.5
Leukemialymphoblastic(MOLT-4)7.3
Liver13.9
Lung9.75
Lymphnode7.6
Lymphoma_burkitts(Daudi)11.7
Lymphoma_burkitts(Raji)12.5
MedullaOblongata8.05
OccipitalLobe7.9
OlfactoryBulb6.8
Ovary6.3
Pancreas5.95
PancreaticIslet9.05
ParietalLobe9.8
Pituitary10.05
Placenta15.05
Pons8.5
PrefrontalCortex10.45
Prostate9.6
Salivarygland8.55
SkeletalMuscle12.05
Skin7.8
SmoothMuscle9.75
Spinalcord9.35
SubthalamicNucleus7.95
SuperiorCervicalGanglion12.3
TemporalLobe8.1
Testis7.65
TestisGermCell6.95
TestisIntersitial7.85
TestisLeydigCell9.1
TestisSeminiferousTubule7.6
Thalamus9.75
Thymus7.15
Thyroid10.8
Tongue8.65
Tonsil9.35
Trachea7.35
TrigeminalGanglion10.1
Uterus6.75
UterusCorpus7.7
WholeBlood8.3
Wholebrain7.2
colon8.65
pineal_day10.28
pineal_night9.72
retina11.35
small_intestine8.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P521927
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.82 ± 0.93
Basal Forebrain2.34 ± 0.17
Basal Part of Pons2.05 ± 0.37
Cerebellar Cortex2.32 ± 0.85
Cerebellar Nuclei2.62 ± 0.7
Claustrum3.18 ± 0.65
Epithalamus2.18 ± 0.68
Frontal Lobe2.19 ± 0.61
Globus Pallidus2.67 ± 0.38
Hypothalamus2.32 ± 0.63
Insula2.22 ± 0.44
Limbic Lobe2.31 ± 0.65
Mesencephalon2.52 ± 0.64
Myelencephalon2.37 ± 0.62
Occipital Lobe2.48 ± 0.68
Parietal Lobe2.33 ± 0.53
Pontine Tegmentum2.36 ± 0.73
Striatum2.48 ± 0.6
Subthalamus2.54 ± 0.69
Temporal Lobe2.26 ± 0.7
Thalamus2.31 ± 0.57
White Matter2.73 ± 0.26
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mocs1CBCerebellum10.89
14.45
Mocs1CTXCerebral cortex11.25
7.93
Mocs1HIPHippocampal region5.43
5.25
Mocs1HPFHippocampal formation7.85
6.53
Mocs1HYHypothalamus11.15
8.42
Mocs1LSXLateral septal complex9.25
6.11
Mocs1MBMidbrain7.76
6.68
Mocs1MYMedulla18.4
20.35
Mocs1OLFOlfactory bulb16.22
13.64
Mocs1PPons21.72
21.63
Mocs1PALPallidum12.79
10.84
Mocs1RHPRetrohippocampal region11.9
8.35
Mocs1sAMYStriatum-like amygdalar nuclei10.07
7.42
Mocs1STRStriatum9.23
6.83
Mocs1STRdStriatum dorsal region9.76
6.75
Mocs1STRvStriatum ventral region7.59
7.28
Mocs1THThalamus15.27
11.51
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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