AutismKB 2.0

Annotation Detail for MPG


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Basic Information Top
Gene Symbol:MPG ( AAG,ADPG,APNG,CRA36.1,MDG,Mid1,PIG11,PIG16,anpg )
Gene Full Name: N-methylpurine-DNA glycosylase
Band: 16p13.3
Quick LinksEntrez ID:4350; OMIM: 156565; Uniprot ID:3MG_HUMAN; ENSEMBL ID: ENSG00000103152; HGNC ID: 7211
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst2 / 6231932
fetus12 / 56401221
neonate2 / 3109764
infant0 / 236200 
juvenile0 / 555560 
adult82 / 193912142
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor8 / 9417884
cervical tumor2 / 3436658
chondrosarcoma5 / 8282360
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor5 / 11936941
germ cell tumor12 / 26384545
glioma9 / 10688384
head and neck tumor3 / 13630222
kidney tumor2 / 6895929
leukemia12 / 95842125
liver tumor3 / 9635931
lung tumor3 / 10312729
lymphoma1 / 7175513
non-neoplasia0 / 972500 
normal119 / 336030735
ovarian tumor2 / 7668226
pancreatic tumor8 / 10461676
primitive neuroectodermal tumor of the CNS13 / 125680103
prostate cancer4 / 10268038
retinoblastoma1 / 4635621
skin tumor22 / 124949176
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites3 / 4001574
bladder1 / 2975733
blood3 / 12347824
bone5 / 7165569
bone marrow16 / 48801327
brain19 / 110098917
cervix2 / 4817141
connective tissue3 / 14925520
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus0 / 202090 
eye5 / 21105423
heart7 / 8962678
intestine19 / 23447281
kidney8 / 21177737
larynx0 / 241450 
liver3 / 20774314
lung11 / 33697432
lymph0 / 442700 
lymph node8 / 9161087
mammary gland8 / 15327152
mouth1 / 6705214
muscle5 / 10771546
nerve0 / 157680 
ovary3 / 10205129
pancreas18 / 21481283
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta13 / 28082546
prostate12 / 18934563
salivary gland1 / 2015549
skin24 / 210574113
spleen1 / 5395218
stomach7 / 9661972
testis5 / 33044215
thymus0 / 811310 
thyroid0 / 474730 
tonsil2 / 16999117
trachea0 / 524130 
umbilical cord2 / 13680146
uterus13 / 23287855
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203686_at
Cell line Expression level Expression bar
721_B_lymphoblasts97.85
Adipocyte22.5
AdrenalCortex27.35
Adrenalgland19.1
Amygdala17.65
Appendix16.95
AtrioventricularNode14.2
BDCA4+_DentriticCells81.85
Bonemarrow22.35
BronchialEpithelialCells73
CD105+_Endothelial17.65
CD14+_Monocytes85.55
CD19+_BCells(neg._sel.)23.55
CD33+_Myeloid33.05
CD34+37.75
CD4+_Tcells24.4
CD56+_NKCells73.05
CD71+_EarlyErythroid16.2
CD8+_Tcells17.75
CardiacMyocytes37.6
Caudatenucleus15.45
Cerebellum13.9
CerebellumPeduncles19.95
CiliaryGanglion12.85
CingulateCortex19.2
Colorectaladenocarcinoma21.7
DorsalRootGanglion13.5
FetalThyroid18.8
Fetalbrain15.1
Fetalliver15
Fetallung20.8
GlobusPallidus14.25
Heart54.5
Hypothalamus17.55
Kidney14.1
Leukemia_chronicMyelogenousK-56222.05
Leukemia_promyelocytic-HL-6016.8
Leukemialymphoblastic(MOLT-4)15.15
Liver68.65
Lung86.85
Lymphnode17.75
Lymphoma_burkitts(Daudi)22.25
Lymphoma_burkitts(Raji)66.1
MedullaOblongata15.1
OccipitalLobe15.25
OlfactoryBulb12.65
Ovary11.85
Pancreas17.55
PancreaticIslet18.35
ParietalLobe18.2
Pituitary19.85
Placenta18.85
Pons16.85
PrefrontalCortex20.35
Prostate89.55
Salivarygland13.75
SkeletalMuscle21.35
Skin13.35
SmoothMuscle59.9
Spinalcord18
SubthalamicNucleus15.8
SuperiorCervicalGanglion20.15
TemporalLobe16.85
Testis14.2
TestisGermCell13.45
TestisIntersitial14.1
TestisLeydigCell16.85
TestisSeminiferousTubule14.75
Thalamus17.45
Thymus15.1
Thyroid94.25
Tongue17.6
Tonsil17.5
Trachea13.15
TrigeminalGanglion17.6
Uterus15.45
UterusCorpus15.5
WholeBlood25.1
Wholebrain30.7
colon16.65
pineal_day21.94
pineal_night19.98
retina19.825
small_intestine15.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_13085_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.38 ± 0.69
Basal Forebrain4 ± 0.34
Basal Part of Pons4.72 ± 0.67
Cerebellar Cortex4.86 ± 0.49
Cerebellar Nuclei4.07 ± 0.54
Claustrum3.54 ± 0.93
Epithalamus4.23 ± 0.84
Frontal Lobe4.59 ± 0.66
Globus Pallidus3.7 ± 0.34
Hypothalamus4.23 ± 0.54
Insula4.56 ± 0.51
Limbic Lobe4.08 ± 0.78
Mesencephalon4.18 ± 0.67
Myelencephalon4.36 ± 0.71
Occipital Lobe3.7 ± 0.76
Parietal Lobe4.28 ± 0.69
Pontine Tegmentum4.21 ± 0.65
Striatum3.76 ± 0.69
Subthalamus4.12 ± 0.72
Temporal Lobe4.53 ± 0.63
Thalamus4.39 ± 0.61
White Matter3.51 ± 0.82
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
MpgCBCerebellum0.44
0.87
MpgCTXCerebral cortex1.04
0.89
MpgHIPHippocampal region2.47
3.01
MpgHPFHippocampal formation5.4
5.02
MpgHYHypothalamus4.71
4.32
MpgLSXLateral septal complex0.28
0.17
MpgMBMidbrain0.27
0.64
MpgMYMedulla0.78
1.49
MpgOLFOlfactory bulb3.97
2.76
MpgPPons0.95
1.82
MpgPALPallidum2.99
2.31
MpgRHPRetrohippocampal region13.4
9.99
MpgsAMYStriatum-like amygdalar nuclei3.02
2.13
MpgSTRStriatum1.25
0.91
MpgSTRdStriatum dorsal region0.54
0.38
MpgSTRvStriatum ventral region3.06
2.24
MpgTHThalamus1.74
1.39
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00000375 31 28 58 AGQPHSSSDAAQAPAEQPHSSSDAAQAPCPR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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