AutismKB 2.0

Annotation Detail for MPI


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Basic Information Top
Gene Symbol:MPI ( FLJ39201,PMI,PMI1 )
Gene Full Name: mannose phosphate isomerase
Band: 15q24.1
Quick LinksEntrez ID:4351; OMIM: 154550; Uniprot ID:MPI_HUMAN; ENSEMBL ID: ENSG00000178802; HGNC ID: 7216
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst1 / 6231916
fetus55 / 56401297
neonate3 / 3109796
infant6 / 23620254
juvenile6 / 55556107
adult135 / 193912169
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor14 / 94178148
cervical tumor10 / 34366290
chondrosarcoma1 / 8282312
colorectal tumor6 / 11424652
esophageal tumor7 / 17290404
gastrointestinal tumor9 / 11936975
germ cell tumor29 / 263845109
glioma15 / 106883140
head and neck tumor9 / 13630266
kidney tumor5 / 6895972
leukemia2 / 9584220
liver tumor8 / 9635983
lung tumor4 / 10312738
lymphoma8 / 71755111
non-neoplasia28 / 97250287
normal390 / 3360307116
ovarian tumor11 / 76682143
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS30 / 125680238
prostate cancer7 / 10268068
retinoblastoma5 / 46356107
skin tumor8 / 12494964
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland8 / 33197240
ascites4 / 4001599
bladder4 / 29757134
blood9 / 12347872
bone4 / 7165555
bone marrow1 / 4880120
brain211 / 1100989191
cervix15 / 48171311
connective tissue10 / 14925566
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus7 / 20209346
eye14 / 21105466
heart17 / 89626189
intestine35 / 234472149
kidney17 / 21177780
larynx0 / 241450 
liver9 / 20774343
lung22 / 33697465
lymph4 / 4427090
lymph node3 / 9161032
mammary gland16 / 153271104
mouth5 / 6705274
muscle9 / 10771583
nerve1 / 1576863
ovary12 / 102051117
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx4 / 4132896
pituitary gland1 / 1658560
placenta25 / 28082589
prostate14 / 18934573
salivary gland1 / 2015549
skin14 / 21057466
spleen6 / 53952111
stomach7 / 9661972
testis51 / 330442154
thymus12 / 81131147
thyroid4 / 4747384
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord1 / 1368073
uterus20 / 23287885
vascular4 / 5178077
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202472_at
Cell line Expression level Expression bar
721_B_lymphoblasts45.05
Adipocyte10.5
AdrenalCortex12.05
Adrenalgland9.25
Amygdala11.8
Appendix11.55
AtrioventricularNode8.45
BDCA4+_DentriticCells17.55
Bonemarrow11.1
BronchialEpithelialCells15.2
CD105+_Endothelial10.95
CD14+_Monocytes16.25
CD19+_BCells(neg._sel.)14.05
CD33+_Myeloid14.15
CD34+14.65
CD4+_Tcells15.75
CD56+_NKCells23.15
CD71+_EarlyErythroid9.9
CD8+_Tcells11
CardiacMyocytes13.45
Caudatenucleus9.45
Cerebellum8.95
CerebellumPeduncles12.5
CiliaryGanglion7.85
CingulateCortex11.3
Colorectaladenocarcinoma11.1
DorsalRootGanglion8.2
FetalThyroid10.65
Fetalbrain10.25
Fetalliver9.8
Fetallung8.9
GlobusPallidus8
Heart14.25
Hypothalamus14.25
Kidney9.55
Leukemia_chronicMyelogenousK-5629.9
Leukemia_promyelocytic-HL-6011.2
Leukemialymphoblastic(MOLT-4)9.2
Liver18.3
Lung12.05
Lymphnode8.7
Lymphoma_burkitts(Daudi)13.85
Lymphoma_burkitts(Raji)15.5
MedullaOblongata9.9
OccipitalLobe9.7
OlfactoryBulb8.75
Ovary7.25
Pancreas8.4
PancreaticIslet11.75
ParietalLobe11.6
Pituitary12.4
Placenta9.4
Pons10.45
PrefrontalCortex14.5
Prostate12.3
Salivarygland8.85
SkeletalMuscle12.2
Skin8.2
SmoothMuscle12.75
Spinalcord12.35
SubthalamicNucleus10.15
SuperiorCervicalGanglion12.3
TemporalLobe10
Testis9.65
TestisGermCell11.5
TestisIntersitial10.25
TestisLeydigCell10.8
TestisSeminiferousTubule9.4
Thalamus11.85
Thymus8.1
Thyroid13.1
Tongue10.5
Tonsil10.3
Trachea9.05
TrigeminalGanglion10.55
Uterus8.5
UterusCorpus9.65
WholeBlood12.05
Wholebrain12.4
colon10.85
pineal_day134.28
pineal_night144.4
retina13.45
small_intestine10.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_8337_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.58 ± 0.81
Basal Forebrain3.22 ± 0.4
Basal Part of Pons3.99 ± 0.57
Cerebellar Cortex3.73 ± 0.55
Cerebellar Nuclei3.34 ± 0.66
Claustrum3.3 ± 0.85
Epithalamus3.42 ± 0.68
Frontal Lobe3.78 ± 0.48
Globus Pallidus3.42 ± 0.66
Hypothalamus3.49 ± 0.39
Insula3.79 ± 0.44
Limbic Lobe3.37 ± 0.62
Mesencephalon3.5 ± 0.63
Myelencephalon3.5 ± 0.64
Occipital Lobe2.87 ± 0.73
Parietal Lobe3.44 ± 0.64
Pontine Tegmentum3.45 ± 0.63
Striatum3.05 ± 0.71
Subthalamus3.84 ± 0.17
Temporal Lobe3.65 ± 0.58
Thalamus3.51 ± 0.66
White Matter3.22 ± 0.86
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mpi1CBCerebellum47.82
92.28
Mpi1CTXCerebral cortex100
100
Mpi1HIPHippocampal region100
100
Mpi1HPFHippocampal formation100
100
Mpi1HYHypothalamus100
100
Mpi1LSXLateral septal complex100
100
Mpi1MBMidbrain100
100
Mpi1MYMedulla91.42
100
Mpi1OLFOlfactory bulb99.02
100
Mpi1PPons82.63
100
Mpi1PALPallidum69.86
81.15
Mpi1RHPRetrohippocampal region100
100
Mpi1sAMYStriatum-like amygdalar nuclei100
100
Mpi1STRStriatum81.2
75.51
Mpi1STRdStriatum dorsal region73.77
69.32
Mpi1STRvStriatum ventral region61.92
52.59
Mpi1THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
MPI_HUMAN_29 27 29 55 LLASSDPLAQIAEDKPYAELWMGTHPR PRIDE
PAp00008268 15 6 20 VFPLSCAVQQYAWGK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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