AutismKB 2.0

Annotation Detail for MPO


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Basic Information Top
Gene Symbol:MPO ( - )
Gene Full Name: myeloperoxidase
Band: 17q22
Quick LinksEntrez ID:4353; OMIM: 606989; Uniprot ID:PERM_HUMAN; ENSEMBL ID: ENSG00000005381; HGNC ID: 7218
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus20 / 56401235
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult365 / 1939121188
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor4 / 13630229
kidney tumor2 / 6895929
leukemia315 / 958423286
liver tumor0 / 963590 
lung tumor4 / 10312738
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal88 / 336030726
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood315 / 1234782551
bone2 / 7165527
bone marrow18 / 48801368
brain53 / 110098948
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye3 / 21105414
heart0 / 896260 
intestine0 / 2344720 
kidney2 / 2117779
larynx0 / 241450 
liver0 / 2077430 
lung4 / 33697411
lymph0 / 442700 
lymph node2 / 9161021
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta7 / 28082524
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus1 / 8113112
thyroid4 / 4747384
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203949_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.85
Adipocyte4.9
AdrenalCortex5.65
Adrenalgland4.25
Amygdala5.2
Appendix6.05
AtrioventricularNode5.3
BDCA4+_DentriticCells5.35
Bonemarrow2195.55
BronchialEpithelialCells4.8
CD105+_Endothelial4.9
CD14+_Monocytes6.65
CD19+_BCells(neg._sel.)6.2
CD33+_Myeloid1881.1
CD34+6195.45
CD4+_Tcells5.2
CD56+_NKCells5.65
CD71+_EarlyErythroid4.7
CD8+_Tcells4.75
CardiacMyocytes6.65
Caudatenucleus4.4
Cerebellum4
CerebellumPeduncles5.7
CiliaryGanglion3.75
CingulateCortex5.1
Colorectaladenocarcinoma4.95
DorsalRootGanglion4.2
FetalThyroid4.8
Fetalbrain4.85
Fetalliver4.7
Fetallung53.7
GlobusPallidus3.7
Heart7
Hypothalamus5.3
Kidney4.1
Leukemia_chronicMyelogenousK-5624.4
Leukemia_promyelocytic-HL-604.4
Leukemialymphoblastic(MOLT-4)3.85
Liver6.75
Lung5.35
Lymphnode4.15
Lymphoma_burkitts(Daudi)6.4
Lymphoma_burkitts(Raji)7.2
MedullaOblongata4.45
OccipitalLobe4.4
OlfactoryBulb3.85
Ovary3.45
Pancreas4
PancreaticIslet5.25
ParietalLobe5.35
Pituitary5.7
Placenta5
Pons4.8
PrefrontalCortex6.1
Prostate6.7
Salivarygland5.4
SkeletalMuscle6.3
Skin4.1
SmoothMuscle5.55
Spinalcord5.25
SubthalamicNucleus4.55
SuperiorCervicalGanglion9.25
TemporalLobe4.55
Testis4.2
TestisGermCell4
TestisIntersitial4.15
TestisLeydigCell4.95
TestisSeminiferousTubule4.35
Thalamus5.05
Thymus4.65
Thyroid6.9
Tongue5.1
Tonsil4.8
Trachea4.1
TrigeminalGanglion18.45
Uterus4
UterusCorpus4.65
WholeBlood5.4
Wholebrain4.05
colon5
pineal_day6.12
pineal_night5.94
retina6.075
small_intestine4.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15822_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.33 ± 1.14
Basal Forebrain2.08 ± 0.41
Basal Part of Pons1.58 ± 0.66
Cerebellar Cortex1.59 ± 0.82
Cerebellar Nuclei1.94 ± 0.69
Claustrum2.65 ± 0.96
Epithalamus1.34 ± 0.81
Frontal Lobe1.76 ± 0.79
Globus Pallidus2.44 ± 0.82
Hypothalamus1.89 ± 0.87
Insula1.97 ± 0.57
Limbic Lobe1.93 ± 0.76
Mesencephalon1.88 ± 0.79
Myelencephalon1.9 ± 0.75
Occipital Lobe1.75 ± 0.82
Parietal Lobe1.89 ± 0.81
Pontine Tegmentum1.81 ± 0.71
Striatum1.81 ± 0.6
Subthalamus1.86 ± 0.72
Temporal Lobe1.76 ± 0.78
Thalamus1.79 ± 0.66
White Matter1.76 ± 0.17
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00034858 13 702 714 IICDNTGITTVSK Peptide Atlas
PERM_HUMAN_219 9 219 227 NGFPVALAR PRIDE
PERM_HUMAN_228 20 228 247 AVSNEIVRFPTDQLTPDQER PRIDE
PERM_HUMAN_236 12 236 247 FPTDQLTPDQER PRIDE
PERM_HUMAN_248 24 248 271 SLMFMQWGQLLDHDLDFTPEPAAR PRIDE
PERM_HUMAN_304 10 304 313 NQADCIPFFR PRIDE
PERM_HUMAN_327 24 327 350 NQINALTSFVDASMVYGSEEPLAR PRIDE
PERM_HUMAN_395 10 395 404 IPCFLAGDTR PRIDE
PERM_HUMAN_405 16 405 420 SSEMPELTSMHTLLLR PRIDE
PERM_HUMAN_447 13 447 459 KIVGAMVQIITYR PRIDE
PERM_HUMAN_460 13 460 472 DYLPLVLGPTAMR PRIDE
PERM_HUMAN_489 10 489 498 IANVFTNAFR PRIDE
PERM_HUMAN_499 12 499 510 YGHTLIQPFMFR PRIDE
PERM_HUMAN_536 12 536 547 VVLEGGIDPILR PRIDE
PERM_HUMAN_559 10 559 568 QNQIAVDEIR PRIDE
PERM_HUMAN_578 12 578 589 IGLDLPALNMQR PRIDE
PERM_HUMAN_603 19 603 621 RFCGLPQPETVGQLGTVLR PRIDE
PERM_HUMAN_604 18 604 621 FCGLPQPETVGQLGTVLR PRIDE
PERM_HUMAN_628 25 628 652 KLMEQYGTPNNIDIWMGGVSEPLKR PRIDE
PERM_HUMAN_656 14 656 669 VGPLLACIIGTQFR PRIDE
PERM_HUMAN_691 10 691 700 QALAQISLPR PRIDE
PERM_HUMAN_692 10 692 701 QALAQISLPR PRIDE
PERM_HUMAN_701 13 701 713 IICDNTGITTVSK PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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