AutismKB 2.0

Annotation Detail for MPP1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:MPP1 ( AAG12,DXS552E,EMP55,MRG1,PEMP )
Gene Full Name: membrane protein, palmitoylated 1, 55kDa
Band: Xq28
Quick LinksEntrez ID:4354; OMIM: 305360; Uniprot ID:EM55_HUMAN; ENSEMBL ID: ENSG00000130830; HGNC ID: 7219
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst1 / 6231916
fetus61 / 564012108
neonate6 / 31097192
infant2 / 2362084
juvenile3 / 5555653
adult144 / 193912174
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor0 / 343660 
chondrosarcoma4 / 8282348
colorectal tumor2 / 11424617
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor12 / 26384545
glioma2 / 10688318
head and neck tumor6 / 13630244
kidney tumor6 / 6895987
leukemia22 / 95842229
liver tumor4 / 9635941
lung tumor12 / 103127116
lymphoma0 / 717550 
non-neoplasia18 / 97250185
normal326 / 336030797
ovarian tumor2 / 7668226
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer1 / 1026809
retinoblastoma3 / 4635664
skin tumor4 / 12494932
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland3 / 3319790
ascites0 / 400150 
bladder3 / 29757100
blood32 / 123478259
bone3 / 7165541
bone marrow12 / 48801245
brain75 / 110098968
cervix1 / 4817120
connective tissue18 / 149255120
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye5 / 21105423
heart5 / 8962655
intestine5 / 23447221
kidney37 / 211777174
larynx0 / 241450 
liver17 / 20774381
lung30 / 33697489
lymph0 / 442700 
lymph node1 / 9161010
mammary gland7 / 15327145
mouth1 / 6705214
muscle0 / 1077150 
nerve0 / 157680 
ovary4 / 10205139
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta63 / 280825224
prostate5 / 18934526
salivary gland1 / 2015549
skin5 / 21057423
spleen14 / 53952259
stomach6 / 9661962
testis5 / 33044215
thymus31 / 81131382
thyroid7 / 47473147
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus8 / 23287834
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202974_at
Cell line Expression level Expression bar
721_B_lymphoblasts16.85
Adipocyte28
AdrenalCortex112.75
Adrenalgland77.1
Amygdala96.15
Appendix107.45
AtrioventricularNode13.7
BDCA4+_DentriticCells119.8
Bonemarrow785.25
BronchialEpithelialCells20.6
CD105+_Endothelial1243.55
CD14+_Monocytes655
CD19+_BCells(neg._sel.)60.4
CD33+_Myeloid669.05
CD34+900.6
CD4+_Tcells23.35
CD56+_NKCells66.2
CD71+_EarlyErythroid3808.75
CD8+_Tcells38.95
CardiacMyocytes45.45
Caudatenucleus82.45
Cerebellum97.5
CerebellumPeduncles68
CiliaryGanglion15.35
CingulateCortex121.55
Colorectaladenocarcinoma43.5
DorsalRootGanglion40.8
FetalThyroid55.8
Fetalbrain34.15
Fetalliver476.7
Fetallung145.75
GlobusPallidus68.65
Heart57.45
Hypothalamus78.55
Kidney91.6
Leukemia_chronicMyelogenousK-562604.9
Leukemia_promyelocytic-HL-6015.55
Leukemialymphoblastic(MOLT-4)152.65
Liver110.2
Lung65.25
Lymphnode93.35
Lymphoma_burkitts(Daudi)75.65
Lymphoma_burkitts(Raji)27.7
MedullaOblongata134.4
OccipitalLobe113.8
OlfactoryBulb32.5
Ovary44.75
Pancreas87.7
PancreaticIslet61.6
ParietalLobe72.3
Pituitary94.3
Placenta280.6
Pons114.45
PrefrontalCortex170.6
Prostate47.85
Salivarygland73.4
SkeletalMuscle38.9
Skin40.7
SmoothMuscle31.95
Spinalcord55.55
SubthalamicNucleus104.1
SuperiorCervicalGanglion34.35
TemporalLobe95.85
Testis44.1
TestisGermCell44.4
TestisIntersitial24.05
TestisLeydigCell51.55
TestisSeminiferousTubule43.35
Thalamus148.25
Thymus280.7
Thyroid79.55
Tongue69.65
Tonsil30.45
Trachea16.4
TrigeminalGanglion41.7
Uterus43.65
UterusCorpus43.05
WholeBlood641.45
Wholebrain102.5
colon26.2
pineal_day107.66
pineal_night100.92
retina68.05
small_intestine158
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P91906
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.21 ± 0.97
Basal Forebrain1.78 ± 0.2
Basal Part of Pons1.46 ± 0.35
Cerebellar Cortex1.74 ± 0.79
Cerebellar Nuclei2.07 ± 0.68
Claustrum2.55 ± 0.73
Epithalamus1.53 ± 0.75
Frontal Lobe1.71 ± 0.7
Globus Pallidus2.38 ± 0.64
Hypothalamus1.83 ± 0.67
Insula1.7 ± 0.49
Limbic Lobe1.77 ± 0.58
Mesencephalon1.94 ± 0.65
Myelencephalon1.78 ± 0.63
Occipital Lobe1.84 ± 0.63
Parietal Lobe1.85 ± 0.64
Pontine Tegmentum1.84 ± 0.66
Striatum1.9 ± 0.47
Subthalamus1.96 ± 0.64
Temporal Lobe1.64 ± 0.53
Thalamus1.75 ± 0.55
White Matter2.18 ± 0.29
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mpp1CBCerebellum7.98
8.23
Mpp1CTXCerebral cortex29.37
13.33
Mpp1HIPHippocampal region20.03
17.43
Mpp1HPFHippocampal formation16.95
12.25
Mpp1HYHypothalamus6.4
2.58
Mpp1LSXLateral septal complex1.54
0.87
Mpp1MBMidbrain13.6
7.24
Mpp1MYMedulla33.06
22.35
Mpp1OLFOlfactory bulb11.25
5.05
Mpp1PPons19.5
12.82
Mpp1PALPallidum8.33
3.99
Mpp1RHPRetrohippocampal region11.73
5.24
Mpp1sAMYStriatum-like amygdalar nuclei6.57
1.83
Mpp1STRStriatum10.6
3.73
Mpp1STRdStriatum dorsal region13.44
4.76
Mpp1STRvStriatum ventral region6.05
2.33
Mpp1THThalamus4.28
2.66
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00032589 25 5 29 ASEGESGGSMHTALSDLYLEHLLQK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved