AutismKB 2.0

Annotation Detail for ABCC1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ABCC1 ( ABC29,ABCC,DKFZp686N04233,DKFZp781G125,GS-X,MRP,MRP1 )
Gene Full Name: ATP-binding cassette, sub-family C (CFTR/MRP), member 1
Band: 16p13.11
Quick LinksEntrez ID:4363; OMIM: 158343; Uniprot ID:MRP1_HUMAN; ENSEMBL ID: ENSG00000103222; HGNC ID: 51
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst10 / 62319160
fetus4 / 5640127
neonate0 / 310970 
infant0 / 236200 
juvenile4 / 5555671
adult105 / 193912154
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma15 / 82823181
colorectal tumor15 / 114246131
esophageal tumor0 / 172900 
gastrointestinal tumor6 / 11936950
germ cell tumor8 / 26384530
glioma3 / 10688328
head and neck tumor25 / 136302183
kidney tumor0 / 689590 
leukemia9 / 9584293
liver tumor0 / 963590 
lung tumor3 / 10312729
lymphoma1 / 7175513
non-neoplasia1 / 9725010
normal76 / 336030722
ovarian tumor1 / 7668213
pancreatic tumor12 / 104616114
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer7 / 10268068
retinoblastoma3 / 4635664
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites2 / 4001549
bladder0 / 297570 
blood5 / 12347840
bone2 / 7165527
bone marrow13 / 48801266
brain16 / 110098914
cervix5 / 48171103
connective tissue13 / 14925587
ear0 / 162120 
embryonic tissue18 / 21572283
esophagus0 / 202090 
eye10 / 21105447
heart0 / 896260 
intestine18 / 23447276
kidney1 / 2117774
larynx2 / 2414582
liver3 / 20774314
lung19 / 33697456
lymph0 / 442700 
lymph node10 / 91610109
mammary gland7 / 15327145
mouth7 / 67052104
muscle3 / 10771527
nerve0 / 157680 
ovary4 / 10205139
pancreas12 / 21481255
parathyroid1 / 2053948
pharynx12 / 41328290
pituitary gland0 / 165850 
placenta3 / 28082510
prostate9 / 18934547
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach3 / 9661931
testis11 / 33044233
thymus3 / 8113136
thyroid4 / 4747384
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus6 / 23287825
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202804_at
Cell line Expression level Expression bar
721_B_lymphoblasts141.1
Adipocyte115.85
AdrenalCortex58.15
Adrenalgland70.25
Amygdala49.8
Appendix61.55
AtrioventricularNode31.5
BDCA4+_DentriticCells149.95
Bonemarrow111.15
BronchialEpithelialCells151
CD105+_Endothelial65.2
CD14+_Monocytes103.35
CD19+_BCells(neg._sel.)78.1
CD33+_Myeloid161.9
CD34+346.25
CD4+_Tcells153.85
CD56+_NKCells68.6
CD71+_EarlyErythroid36.8
CD8+_Tcells132.7
CardiacMyocytes82.7
Caudatenucleus44.1
Cerebellum49.45
CerebellumPeduncles51.3
CiliaryGanglion26.7
CingulateCortex55.1
Colorectaladenocarcinoma57.5
DorsalRootGanglion33.8
FetalThyroid88.7
Fetalbrain49.1
Fetalliver43.1
Fetallung93.05
GlobusPallidus32.35
Heart85.35
Hypothalamus46.3
Kidney49.65
Leukemia_chronicMyelogenousK-56274
Leukemia_promyelocytic-HL-60111.65
Leukemialymphoblastic(MOLT-4)115.7
Liver69
Lung106.9
Lymphnode112.9
Lymphoma_burkitts(Daudi)147.75
Lymphoma_burkitts(Raji)155.9
MedullaOblongata43.15
OccipitalLobe34.4
OlfactoryBulb33.85
Ovary41.7
Pancreas31.4
PancreaticIslet41.8
ParietalLobe67.35
Pituitary54.45
Placenta53.85
Pons56
PrefrontalCortex39.85
Prostate103.9
Salivarygland49.35
SkeletalMuscle68.95
Skin38.35
SmoothMuscle159.1
Spinalcord66.95
SubthalamicNucleus36.15
SuperiorCervicalGanglion67.7
TemporalLobe35.95
Testis180.9
TestisGermCell174.15
TestisIntersitial87.1
TestisLeydigCell91.75
TestisSeminiferousTubule92.05
Thalamus40.3
Thymus151.2
Thyroid94.95
Tongue71.5
Tonsil105.3
Trachea95.4
TrigeminalGanglion39.55
Uterus58.8
UterusCorpus63.6
WholeBlood85
Wholebrain35.3
colon53.05
pineal_day65.1
pineal_night54.46
retina110.45
small_intestine53.2
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15970_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.04 ± 0.45
Basal Forebrain4.84 ± 0.26
Basal Part of Pons5.01 ± 0.36
Cerebellar Cortex4.79 ± 0.44
Cerebellar Nuclei5.04 ± 0.37
Claustrum5.06 ± 0.81
Epithalamus4.91 ± 0.37
Frontal Lobe4.77 ± 0.37
Globus Pallidus5.06 ± 0.48
Hypothalamus4.78 ± 0.6
Insula4.61 ± 0.46
Limbic Lobe5.06 ± 0.41
Mesencephalon4.91 ± 0.56
Myelencephalon4.94 ± 0.44
Occipital Lobe5.37 ± 0.41
Parietal Lobe4.99 ± 0.38
Pontine Tegmentum4.86 ± 0.42
Striatum5 ± 0.39
Subthalamus4.64 ± 0.51
Temporal Lobe4.91 ± 0.38
Thalamus4.84 ± 0.36
White Matter4.66 ± 0.38
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Abcc1CBCerebellum6.21
6.53
Abcc1CTXCerebral cortex7.58
4.93
Abcc1HIPHippocampal region7.59
7.08
Abcc1HPFHippocampal formation8.43
7.07
Abcc1HYHypothalamus1.26
1.09
Abcc1LSXLateral septal complex1.25
0.9
Abcc1MBMidbrain2.14
2.25
Abcc1MYMedulla5.64
5.61
Abcc1OLFOlfactory bulb13.22
10.85
Abcc1PPons3.38
3.66
Abcc1PALPallidum1.64
1.16
Abcc1RHPRetrohippocampal region10.28
7.19
Abcc1sAMYStriatum-like amygdalar nuclei2.34
1.44
Abcc1STRStriatum3.05
1.91
Abcc1STRdStriatum dorsal region3.43
2.16
Abcc1STRvStriatum ventral region2.25
1.3
Abcc1THThalamus2.54
1.87
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
MRP1_HUMAN_1059 8 1059 1066 SPMSFFER PRIDE
PAp00039585 24 781 804 AVYSNADIYLFDDPLSAVDAHVGK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved