AutismKB 2.0

Annotation Detail for ASMT


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Basic Information Top
Gene Symbol:ASMT ( ASMTY,HIOMT,HIOMTY )
Gene Full Name: acetylserotonin O-methyltransferase
Band: Xp22.3 and Yp11.3
Quick LinksEntrez ID:438; OMIM: 300015,402500; Uniprot ID:HIOM_HUMAN; ENSEMBL ID: ENSG00000196433; HGNC ID: 750
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 206779_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.25
Adipocyte8.7
AdrenalCortex11.05
Adrenalgland8.1
Amygdala8.3
Appendix12.3
AtrioventricularNode10.8
BDCA4+_DentriticCells8.65
Bonemarrow10.7
BronchialEpithelialCells8.3
CD105+_Endothelial8.75
CD14+_Monocytes9.45
CD19+_BCells(neg._sel.)9.15
CD33+_Myeloid11.15
CD34+10.7
CD4+_Tcells8.7
CD56+_NKCells9.75
CD71+_EarlyErythroid8.8
CD8+_Tcells7.85
CardiacMyocytes19.7
Caudatenucleus7.9
Cerebellum7.35
CerebellumPeduncles10.45
CiliaryGanglion7.65
CingulateCortex9.25
Colorectaladenocarcinoma8.9
DorsalRootGanglion8.65
FetalThyroid9.15
Fetalbrain8.65
Fetalliver8.15
Fetallung6.3
GlobusPallidus7.55
Heart17.85
Hypothalamus9.25
Kidney8.7
Leukemia_chronicMyelogenousK-5628
Leukemia_promyelocytic-HL-607.75
Leukemialymphoblastic(MOLT-4)6.55
Liver14.15
Lung9.75
Lymphnode7.4
Lymphoma_burkitts(Daudi)11.75
Lymphoma_burkitts(Raji)15.05
MedullaOblongata7.7
OccipitalLobe7.9
OlfactoryBulb6.9
Ovary6.4
Pancreas7.55
PancreaticIslet9.65
ParietalLobe10.45
Pituitary10.1
Placenta8.7
Pons8.75
PrefrontalCortex10.6
Prostate10.2
Salivarygland9.95
SkeletalMuscle16.35
Skin7.8
SmoothMuscle9.8
Spinalcord9.2
SubthalamicNucleus9.05
SuperiorCervicalGanglion15.6
TemporalLobe8.5
Testis7.5
TestisGermCell6.9
TestisIntersitial7.85
TestisLeydigCell9.6
TestisSeminiferousTubule7.6
Thalamus9.25
Thymus6.4
Thyroid10.8
Tongue9.35
Tonsil9.05
Trachea7.35
TrigeminalGanglion12.35
Uterus6.9
UterusCorpus9.3
WholeBlood9.25
Wholebrain6.6
colon8.7
pineal_day3620.32
pineal_night3043.06
retina10.975
small_intestine8.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P255535
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala1.98 ± 1.1
Basal Forebrain1.57 ± 0.26
Basal Part of Pons1.26 ± 0.39
Cerebellar Cortex1.64 ± 0.68
Cerebellar Nuclei1.9 ± 0.69
Claustrum2.36 ± 0.73
Epithalamus1.51 ± 0.76
Frontal Lobe1.6 ± 0.66
Globus Pallidus2.23 ± 0.64
Hypothalamus1.9 ± 0.64
Insula1.36 ± 0.81
Limbic Lobe1.57 ± 0.64
Mesencephalon2.09 ± 0.78
Myelencephalon1.72 ± 0.68
Occipital Lobe1.68 ± 0.79
Parietal Lobe1.71 ± 0.72
Pontine Tegmentum1.62 ± 0.59
Striatum1.57 ± 0.64
Subthalamus1.68 ± 0.66
Temporal Lobe1.6 ± 0.73
Thalamus1.53 ± 0.59
White Matter2.04 ± 0.44
Mouse Brain ISH
Peptide Top

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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