AutismKB 2.0

Annotation Detail for MYO1B


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Basic Information Top
Gene Symbol:MYO1B ( myr1 )
Gene Full Name: myosin IB
Band: 2q32.3
Quick LinksEntrez ID:4430; OMIM: 606537; Uniprot ID:MYO1B_HUMAN; ENSEMBL ID: ENSG00000128641; HGNC ID: 7596
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst6 / 6231996
fetus38 / 56401267
neonate1 / 3109732
infant0 / 236200 
juvenile0 / 555560 
adult210 / 1939121108
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma1 / 1747557
breast (mammary gland) tumor22 / 94178233
cervical tumor0 / 343660 
chondrosarcoma8 / 8282396
colorectal tumor29 / 114246253
esophageal tumor1 / 1729057
gastrointestinal tumor8 / 11936967
germ cell tumor14 / 26384553
glioma7 / 10688365
head and neck tumor57 / 136302418
kidney tumor1 / 6895914
leukemia2 / 9584220
liver tumor14 / 96359145
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal180 / 336030753
ovarian tumor2 / 7668226
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer3 / 10268029
retinoblastoma1 / 4635621
skin tumor9 / 12494972
soft tissue/muscle tissue tumor23 / 125191183
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites3 / 4001574
bladder5 / 29757168
blood0 / 1234780 
bone5 / 7165569
bone marrow3 / 4880161
brain27 / 110098924
cervix0 / 481710 
connective tissue27 / 149255180
ear4 / 16212246
embryonic tissue29 / 215722134
esophagus1 / 2020949
eye12 / 21105456
heart5 / 8962655
intestine33 / 234472140
kidney9 / 21177742
larynx1 / 2414541
liver27 / 207743129
lung29 / 33697486
lymph0 / 442700 
lymph node5 / 9161054
mammary gland26 / 153271169
mouth50 / 67052745
muscle5 / 10771546
nerve2 / 15768126
ovary3 / 10205129
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx5 / 41328120
pituitary gland0 / 165850 
placenta15 / 28082553
prostate9 / 18934547
salivary gland1 / 2015549
skin16 / 21057475
spleen0 / 539520 
stomach9 / 9661993
testis13 / 33044239
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord0 / 136800 
uterus9 / 23287838
vascular2 / 5178038
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212364_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.65
Adipocyte14.8
AdrenalCortex11.75
Adrenalgland7.25
Amygdala7.35
Appendix48.7
AtrioventricularNode11.65
BDCA4+_DentriticCells6.25
Bonemarrow9
BronchialEpithelialCells510.2
CD105+_Endothelial7.45
CD14+_Monocytes8.3
CD19+_BCells(neg._sel.)8.75
CD33+_Myeloid8.55
CD34+8.45
CD4+_Tcells6.25
CD56+_NKCells7.9
CD71+_EarlyErythroid7.4
CD8+_Tcells5.9
CardiacMyocytes46.8
Caudatenucleus7.05
Cerebellum5.8
CerebellumPeduncles10.45
CiliaryGanglion13.35
CingulateCortex9.7
Colorectaladenocarcinoma8.7
DorsalRootGanglion12.9
FetalThyroid10.8
Fetalbrain10.75
Fetalliver32.45
Fetallung142.2
GlobusPallidus7.7
Heart13.5
Hypothalamus8.95
Kidney8
Leukemia_chronicMyelogenousK-5626.5
Leukemia_promyelocytic-HL-606.15
Leukemialymphoblastic(MOLT-4)10
Liver16.85
Lung9.95
Lymphnode7.25
Lymphoma_burkitts(Daudi)10.35
Lymphoma_burkitts(Raji)12.6
MedullaOblongata9.75
OccipitalLobe6.9
OlfactoryBulb46.15
Ovary8.95
Pancreas36.4
PancreaticIslet168.75
ParietalLobe10.5
Pituitary9
Placenta10.55
Pons9.3
PrefrontalCortex17.6
Prostate12.05
Salivarygland7.25
SkeletalMuscle16.5
Skin12.45
SmoothMuscle238.95
Spinalcord7.65
SubthalamicNucleus8.75
SuperiorCervicalGanglion23.9
TemporalLobe8.1
Testis6.2
TestisGermCell6.8
TestisIntersitial7.1
TestisLeydigCell9.8
TestisSeminiferousTubule6.8
Thalamus15.4
Thymus5.65
Thyroid21.25
Tongue10
Tonsil8.55
Trachea7.2
TrigeminalGanglion16.1
Uterus30
UterusCorpus12.6
WholeBlood7.6
Wholebrain5.6
colon75.3
pineal_day9.38
pineal_night8.82
retina10.5
small_intestine16.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P361049
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.64 ± 0.42
Basal Forebrain5.86 ± 0.33
Basal Part of Pons5.51 ± 0.43
Cerebellar Cortex5.34 ± 0.43
Cerebellar Nuclei6.35 ± 0.28
Claustrum6.25 ± 0.66
Epithalamus5.52 ± 0.84
Frontal Lobe6.4 ± 0.63
Globus Pallidus6.08 ± 0.69
Hypothalamus5.74 ± 0.83
Insula6.14 ± 0.57
Limbic Lobe5.84 ± 0.76
Mesencephalon6.14 ± 0.49
Myelencephalon6.17 ± 0.73
Occipital Lobe6.6 ± 0.8
Parietal Lobe6.29 ± 0.63
Pontine Tegmentum6.37 ± 0.72
Striatum6.19 ± 0.71
Subthalamus5.97 ± 0.28
Temporal Lobe6.11 ± 0.73
Thalamus6.98 ± 0.72
White Matter4.83 ± 0.11
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Myo1bCBCerebellum25.94
40.99
Myo1bCTXCerebral cortex76.41
69.94
Myo1bHIPHippocampal region20.85
26.01
Myo1bHPFHippocampal formation30.85
32.38
Myo1bHYHypothalamus20.18
15.3
Myo1bLSXLateral septal complex23.87
18.65
Myo1bMBMidbrain29.85
25.99
Myo1bMYMedulla18.14
18.69
Myo1bOLFOlfactory bulb59.12
53.17
Myo1bPPons19.26
18.36
Myo1bPALPallidum22.4
19.08
Myo1bRHPRetrohippocampal region42.94
38.29
Myo1bsAMYStriatum-like amygdalar nuclei38.49
29.32
Myo1bSTRStriatum81.83
76.15
Myo1bSTRdStriatum dorsal region90.68
83.36
Myo1bSTRvStriatum ventral region80.73
75.91
Myo1bTHThalamus63.31
60.8
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
MYO1B_HUMAN_1006 15 1006 1020 IFLLTNNNLLLADQK PRIDE
MYO1B_HUMAN_1061 16 1061 1076 GDFLFSSDHLIEMATK PRIDE
MYO1B_HUMAN_169 9 169 177 YMDIEFDFK PRIDE
MYO1B_HUMAN_203 19 203 221 NFHVFYQLLSGASEELLNK PRIDE
PAp00002040 24 1053 1076 EGSEAASKGDFLFSSDHLIEMATK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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