AutismKB 2.0

Annotation Detail for MSN


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Basic Information Top
Gene Symbol:MSN ( - )
Gene Full Name: moesin
Band: Xq12
Quick LinksEntrez ID:4478; OMIM: 309845; Uniprot ID:MOES_HUMAN; ENSEMBL ID: ENSG00000147065; HGNC ID: 7373
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body48 / 70761678
blastocyst10 / 62319160
fetus44 / 56401278
neonate0 / 310970 
infant0 / 236200 
juvenile7 / 55556125
adult352 / 1939121181
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma3 / 17475171
breast (mammary gland) tumor29 / 94178307
cervical tumor8 / 34366232
chondrosarcoma23 / 82823277
colorectal tumor6 / 11424652
esophageal tumor2 / 17290115
gastrointestinal tumor5 / 11936941
germ cell tumor31 / 263845117
glioma17 / 106883159
head and neck tumor41 / 136302300
kidney tumor20 / 68959290
leukemia57 / 95842594
liver tumor22 / 96359228
lung tumor9 / 10312787
lymphoma19 / 71755264
non-neoplasia14 / 97250143
normal362 / 3360307107
ovarian tumor10 / 76682130
pancreatic tumor19 / 104616181
primitive neuroectodermal tumor of the CNS3 / 12568023
prostate cancer14 / 102680136
retinoblastoma0 / 463560 
skin tumor64 / 124949512
soft tissue/muscle tissue tumor18 / 125191143
uterine tumor8 / 9025788
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue5 / 13106381
adrenal gland1 / 3319730
ascites1 / 4001524
bladder3 / 29757100
blood55 / 123478445
bone13 / 71655181
bone marrow13 / 48801266
brain67 / 110098960
cervix8 / 48171166
connective tissue22 / 149255147
ear2 / 16212123
embryonic tissue65 / 215722301
esophagus2 / 2020998
eye16 / 21105475
heart15 / 89626167
intestine12 / 23447251
kidney27 / 211777127
larynx9 / 24145372
liver27 / 207743129
lung50 / 336974148
lymph4 / 4427090
lymph node20 / 91610218
mammary gland37 / 153271241
mouth13 / 67052193
muscle15 / 107715139
nerve5 / 15768317
ovary12 / 102051117
pancreas25 / 214812116
parathyroid1 / 2053948
pharynx8 / 41328193
pituitary gland0 / 165850 
placenta29 / 280825103
prostate15 / 18934579
salivary gland2 / 2015599
skin84 / 210574398
spleen13 / 53952240
stomach6 / 9661962
testis19 / 33044257
thymus5 / 8113161
thyroid24 / 47473505
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus35 / 232878150
vascular9 / 51780173
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 200600_at
Cell line Expression level Expression bar
721_B_lymphoblasts1508.25
Adipocyte399.25
AdrenalCortex53
Adrenalgland299.15
Amygdala97.35
Appendix166.7
AtrioventricularNode96.2
BDCA4+_DentriticCells936.7
Bonemarrow770.95
BronchialEpithelialCells1321.35
CD105+_Endothelial356.15
CD14+_Monocytes1555.6
CD19+_BCells(neg._sel.)1058.8
CD33+_Myeloid2877.05
CD34+1123.35
CD4+_Tcells1301.05
CD56+_NKCells3100.95
CD71+_EarlyErythroid33.2
CD8+_Tcells1532.2
CardiacMyocytes898.3
Caudatenucleus88.8
Cerebellum83.15
CerebellumPeduncles27.7
CiliaryGanglion110.1
CingulateCortex23.6
Colorectaladenocarcinoma363.75
DorsalRootGanglion122.05
FetalThyroid300.1
Fetalbrain69.65
Fetalliver69.45
Fetallung758.3
GlobusPallidus12.4
Heart125.2
Hypothalamus187.25
Kidney350.4
Leukemia_chronicMyelogenousK-562687.05
Leukemia_promyelocytic-HL-60206.15
Leukemialymphoblastic(MOLT-4)653.65
Liver31.1
Lung717.2
Lymphnode557.55
Lymphoma_burkitts(Daudi)255.3
Lymphoma_burkitts(Raji)189.25
MedullaOblongata44.25
OccipitalLobe60.9
OlfactoryBulb369.95
Ovary153.8
Pancreas31.4
PancreaticIslet195.8
ParietalLobe24.4
Pituitary148.7
Placenta455.95
Pons39.4
PrefrontalCortex197.65
Prostate89.45
Salivarygland198.15
SkeletalMuscle19.75
Skin97.5
SmoothMuscle1100.9
Spinalcord395
SubthalamicNucleus19.85
SuperiorCervicalGanglion60.95
TemporalLobe27.1
Testis76.4
TestisGermCell87.75
TestisIntersitial21.9
TestisLeydigCell39.55
TestisSeminiferousTubule14.9
Thalamus80.05
Thymus754.65
Thyroid605
Tongue83.05
Tonsil422.1
Trachea200.65
TrigeminalGanglion64.65
Uterus443.7
UterusCorpus129.8
WholeBlood2772.5
Wholebrain46.75
colon231.2
pineal_day145.24
pineal_night123.62
retina897.025
small_intestine464.9
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P151102
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.57 ± 0.63
Basal Forebrain4.92 ± 0.37
Basal Part of Pons3.96 ± 0.56
Cerebellar Cortex4.23 ± 0.42
Cerebellar Nuclei4.87 ± 0.48
Claustrum5.2 ± 0.63
Epithalamus5.9 ± 0.4
Frontal Lobe4.64 ± 0.64
Globus Pallidus6.42 ± 0.42
Hypothalamus5.24 ± 0.89
Insula4.46 ± 0.46
Limbic Lobe4.49 ± 0.72
Mesencephalon4.9 ± 0.61
Myelencephalon4.83 ± 0.65
Occipital Lobe4.68 ± 0.85
Parietal Lobe4.64 ± 0.65
Pontine Tegmentum4.94 ± 0.62
Striatum5.57 ± 0.53
Subthalamus4.44 ± 0.39
Temporal Lobe4.42 ± 0.64
Thalamus4.95 ± 0.53
White Matter6.07 ± 0.39
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
MsnCBCerebellum20.48
44.26
MsnCTXCerebral cortex16.17
13.12
MsnHIPHippocampal region14.74
20.14
MsnHPFHippocampal formation18.18
20.27
MsnHYHypothalamus2.58
2.69
MsnLSXLateral septal complex1.68
1.64
MsnMBMidbrain3.21
4.77
MsnMYMedulla9.96
16.61
MsnOLFOlfactory bulb18.42
16.18
MsnPPons6.04
11.52
MsnPALPallidum7.31
8.64
MsnRHPRetrohippocampal region24.74
21.02
MsnsAMYStriatum-like amygdalar nuclei20.46
17.43
MsnSTRStriatum11.17
10.88
MsnSTRdStriatum dorsal region11.55
11.72
MsnSTRvStriatum ventral region8.48
8.19
MsnTHThalamus4.98
5.66
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
MOES_HUMAN_0 0 0 0 APDFVFYAPR PRIDE
MOES_HUMAN_0 0 0 0 EGILNDDIYCPPETAVLLASYAVQSK PRIDE
MOES_HUMAN_0 0 0 0 FYPEDVSEELIQDITQR PRIDE
MOES_HUMAN_0 0 0 0 IGFPWSEIR PRIDE
MOES_HUMAN_1 7 1 7 PKTISVR PRIDE
MOES_HUMAN_101 7 101 107 LFFLQVK PRIDE
MOES_HUMAN_107 26 107 132 EGILNDDIYCPPETAVLLASYAVQSK PRIDE
MOES_HUMAN_143 13 143 155 SGYLAGDKLLPQR PRIDE
MOES_HUMAN_156 15 156 170 VLEQHKLNKDQWEER PRIDE
MOES_HUMAN_180 13 180 192 GMLREDAVLEYLK PRIDE
MOES_HUMAN_184 9 184 192 EDAVLEYLK PRIDE
MOES_HUMAN_193 16 193 208 IAQDLEMYGVNYFSIK PRIDE
MOES_HUMAN_2 7 2 8 PKTISVR PRIDE
MOES_HUMAN_211 22 211 232 KGSELWLGVDALGLNIYEQNDR PRIDE
MOES_HUMAN_212 25 212 236 GSELWLGVDALGLNIYEQNDRLTPK PRIDE
MOES_HUMAN_237 9 237 245 IGFPWSEIR PRIDE
MOES_HUMAN_238 9 238 246 IGFPWSEIR PRIDE
MOES_HUMAN_254 8 254 261 FVIKPIDK PRIDE
MOES_HUMAN_262 11 262 272 KAPDFVFYAPR PRIDE
MOES_HUMAN_263 10 263 272 APDFVFYAPR PRIDE
MOES_HUMAN_263 11 263 273 KAPDFVFYAPR PRIDE
MOES_HUMAN_264 10 264 273 APDFVFYAPR PRIDE
MOES_HUMAN_27 8 27 34 QLFDQVVK PRIDE
MOES_HUMAN_279 14 279 292 ILALCMGNHELYMR PRIDE
MOES_HUMAN_293 13 293 305 RRKPDTIEVQQMK PRIDE
MOES_HUMAN_294 12 294 305 RKPDTIEVQQMK PRIDE
MOES_HUMAN_295 11 295 305 KPDTIEVQQMK PRIDE
MOES_HUMAN_296 11 296 306 KPDTIEVQQMK PRIDE
MOES_HUMAN_342 10 342 351 EKEELMERLK PRIDE
MOES_HUMAN_342 8 342 349 EKEELMER PRIDE
MOES_HUMAN_359 11 359 369 KAQQELEEQTR PRIDE
MOES_HUMAN_359 12 359 370 KAQQELEEQTRR PRIDE
MOES_HUMAN_382 11 382 392 QSEAEKLAKER PRIDE
MOES_HUMAN_391 17 391 407 ERQEAEEAKEALLQASR PRIDE
MOES_HUMAN_393 15 393 407 QEAEEAKEALLQASR PRIDE
MOES_HUMAN_40 13 40 52 EVWFFGLQYQDTK PRIDE
MOES_HUMAN_408 19 408 426 DQKKTQEQLALEMAELTAR PRIDE
MOES_HUMAN_411 16 411 426 KTQEQLALEMAELTAR PRIDE
MOES_HUMAN_412 15 412 426 TQEQLALEMAELTAR PRIDE
MOES_HUMAN_427 8 427 434 ISQLEMAR PRIDE
MOES_HUMAN_428 8 428 435 ISQLEMAR PRIDE
MOES_HUMAN_438 10 438 447 ESEAVEWQQK PRIDE
MOES_HUMAN_448 10 448 457 AQMVQEDLEK PRIDE
MOES_HUMAN_448 12 448 459 AQMVQEDLEKTR PRIDE
MOES_HUMAN_448 16 448 463 AQMVQEDLEKTRAELK PRIDE
MOES_HUMAN_509 9 509 517 TTEAEKNER PRIDE
MOES_HUMAN_518 15 518 532 QKHLKALTSELANAR PRIDE
MOES_HUMAN_523 10 523 532 ALTSELANAR PRIDE
MOES_HUMAN_523 14 523 536 ALTSELANARDESK PRIDE
MOES_HUMAN_523 15 523 537 ALTSELANARDESKK PRIDE
MOES_HUMAN_524 10 524 533 ALTSELANAR PRIDE
MOES_HUMAN_53 7 53 59 GFSTWLK PRIDE
MOES_HUMAN_537 13 537 549 KTANDMIHAENMR PRIDE
MOES_HUMAN_538 12 538 549 TANDMIHAENMR PRIDE
MOES_HUMAN_568 9 568 576 QRIDEFESM PRIDE
MOES_HUMAN_71 10 71 80 KESPLLFKFR PRIDE
MOES_HUMAN_71 8 71 78 KESPLLFK PRIDE
MOES_HUMAN_8 19 8 26 VTTMDAELEFAIQPNTTGK PRIDE
MOES_HUMAN_81 19 81 99 AKFYPEDVSEELIQDITQR PRIDE
MOES_HUMAN_83 17 83 99 FYPEDVSEELIQDITQR PRIDE
MOES_HUMAN_84 17 84 100 FYPEDVSEELIQDITQR PRIDE
PAp00002022 26 108 133 EGILNDDIYCPPETAVLLASYAVQSK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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