AutismKB 2.0

Annotation Detail for MSRA


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Basic Information Top
Gene Symbol:MSRA ( - )
Gene Full Name: methionine sulfoxide reductase A
Band: 8p23.1
Quick LinksEntrez ID:4482; OMIM: 601250; Uniprot ID:MSRA_HUMAN; ENSEMBL ID: ENSG00000175806; HGNC ID: 7377
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus25 / 56401244
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult41 / 193912121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor3 / 26384511
glioma3 / 10688328
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal93 / 336030727
ovarian tumor2 / 7668226
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor17 / 125191135
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone1 / 7165513
bone marrow0 / 488010 
brain37 / 110098933
cervix0 / 481710 
connective tissue15 / 149255100
ear2 / 16212123
embryonic tissue2 / 2157229
esophagus0 / 202090 
eye9 / 21105442
heart3 / 8962633
intestine2 / 2344728
kidney25 / 211777118
larynx0 / 241450 
liver1 / 2077434
lung5 / 33697414
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary2 / 10205119
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate3 / 18934515
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis6 / 33044218
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus4 / 23287817
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219281_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.3
Adipocyte13.7
AdrenalCortex6.05
Adrenalgland10.3
Amygdala45.7
Appendix10.95
AtrioventricularNode6.1
BDCA4+_DentriticCells15.8
Bonemarrow30.1
BronchialEpithelialCells12.6
CD105+_Endothelial7.55
CD14+_Monocytes31.55
CD19+_BCells(neg._sel.)16.9
CD33+_Myeloid40.05
CD34+21.7
CD4+_Tcells9.15
CD56+_NKCells15.35
CD71+_EarlyErythroid5.3
CD8+_Tcells8.85
CardiacMyocytes9.2
Caudatenucleus12.25
Cerebellum26.95
CerebellumPeduncles20.05
CiliaryGanglion7.35
CingulateCortex18
Colorectaladenocarcinoma9.9
DorsalRootGanglion9
FetalThyroid10.7
Fetalbrain49.55
Fetalliver10.85
Fetallung12.9
GlobusPallidus9.4
Heart32
Hypothalamus29.1
Kidney466.6
Leukemia_chronicMyelogenousK-5628.65
Leukemia_promyelocytic-HL-607.95
Leukemialymphoblastic(MOLT-4)6.65
Liver314.95
Lung26.55
Lymphnode9.1
Lymphoma_burkitts(Daudi)13.5
Lymphoma_burkitts(Raji)14.8
MedullaOblongata14.05
OccipitalLobe12.8
OlfactoryBulb10
Ovary7.7
Pancreas9.75
PancreaticIslet11.85
ParietalLobe12.85
Pituitary13.4
Placenta9.8
Pons11.45
PrefrontalCortex28.4
Prostate24
Salivarygland8.75
SkeletalMuscle13.2
Skin5.7
SmoothMuscle13.65
Spinalcord19.8
SubthalamicNucleus12.1
SuperiorCervicalGanglion10.2
TemporalLobe12.1
Testis11.2
TestisGermCell7.7
TestisIntersitial6.6
TestisLeydigCell7.4
TestisSeminiferousTubule8.15
Thalamus13.3
Thymus9.55
Thyroid36.05
Tongue11.85
Tonsil8.25
Trachea9.05
TrigeminalGanglion11.4
Uterus10.55
UterusCorpus10.3
WholeBlood19.7
Wholebrain37.65
colon20.65
pineal_day12.16
pineal_night12.5
retina35.05
small_intestine46.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P138359
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.78 ± 0.63
Basal Forebrain7.99 ± 0.51
Basal Part of Pons7.46 ± 0.39
Cerebellar Cortex7.25 ± 0.24
Cerebellar Nuclei8.2 ± 0.41
Claustrum8.22 ± 0.81
Epithalamus6.85 ± 0.56
Frontal Lobe7.72 ± 0.52
Globus Pallidus8.31 ± 0.75
Hypothalamus7.45 ± 0.4
Insula7.57 ± 0.42
Limbic Lobe7.73 ± 0.61
Mesencephalon7.9 ± 0.47
Myelencephalon7.77 ± 0.64
Occipital Lobe7.83 ± 0.66
Parietal Lobe7.69 ± 0.51
Pontine Tegmentum7.81 ± 0.58
Striatum8.33 ± 0.49
Subthalamus7.73 ± 0.31
Temporal Lobe7.55 ± 0.56
Thalamus8.03 ± 0.46
White Matter7.46 ± 0.41
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
MsraCBCerebellum30.36
36.35
MsraCTXCerebral cortex40.08
30.02
MsraHIPHippocampal region54.39
92.17
MsraHPFHippocampal formation49.59
70.16
MsraHYHypothalamus1.07
0.78
MsraLSXLateral septal complex3.53
2.95
MsraMBMidbrain3.59
3.75
MsraMYMedulla4.85
4.82
MsraOLFOlfactory bulb29
26.71
MsraPPons6.01
6.5
MsraPALPallidum1.02
0.86
MsraRHPRetrohippocampal region40.11
36.73
MsrasAMYStriatum-like amygdalar nuclei2.82
2.15
MsraSTRStriatum9.11
6.34
MsraSTRdStriatum dorsal region10.2
6.92
MsraSTRvStriatum ventral region12.17
8.41
MsraTHThalamus8.3
9.25
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
MSRA_HUMAN_181 15 181 195 VLSEHGFGPITTDIR PRIDE

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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