AutismKB 2.0

Annotation Detail for MST1R


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Basic Information Top
Gene Symbol:MST1R ( CD136,CDw136,PTK8,RON )
Gene Full Name: macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
Band: 3p21.31
Quick LinksEntrez ID:4486; OMIM: 600168; Uniprot ID:RON_HUMAN; ENSEMBL ID: ENSG00000164078; HGNC ID: 7381
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus3 / 5640125
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult38 / 193912119
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor3 / 3436687
chondrosarcoma0 / 828230 
colorectal tumor16 / 114246140
esophageal tumor0 / 172900 
gastrointestinal tumor9 / 11936975
germ cell tumor1 / 2638453
glioma0 / 1068830 
head and neck tumor1 / 1363027
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal14 / 33603074
ovarian tumor0 / 766820 
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer11 / 102680107
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites2 / 4001549
bladder1 / 2975733
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix3 / 4817162
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine21 / 23447289
kidney0 / 2117770 
larynx1 / 2414541
liver0 / 2077430 
lung5 / 33697414
lymph0 / 442700 
lymph node0 / 916100 
mammary gland3 / 15327119
mouth1 / 6705214
muscle2 / 10771518
nerve0 / 157680 
ovary0 / 1020510 
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate13 / 18934568
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach7 / 9661972
testis4 / 33044212
thymus1 / 8113112
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus3 / 23287812
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205455_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.15
Adipocyte7.25
AdrenalCortex8.85
Adrenalgland6.45
Amygdala7.45
Appendix7.35
AtrioventricularNode5.5
BDCA4+_DentriticCells7.6
Bonemarrow7.2
BronchialEpithelialCells19.7
CD105+_Endothelial7
CD14+_Monocytes7.6
CD19+_BCells(neg._sel.)7.55
CD33+_Myeloid8.75
CD34+8.2
CD4+_Tcells7.6
CD56+_NKCells7.8
CD71+_EarlyErythroid6.8
CD8+_Tcells6.85
CardiacMyocytes9.6
Caudatenucleus6.6
Cerebellum6.3
CerebellumPeduncles8.75
CiliaryGanglion5.05
CingulateCortex8.15
Colorectaladenocarcinoma78
DorsalRootGanglion5.55
FetalThyroid7.55
Fetalbrain7.1
Fetalliver6.6
Fetallung6.15
GlobusPallidus5.35
Heart10.6
Hypothalamus7.95
Kidney6.4
Leukemia_chronicMyelogenousK-5626.65
Leukemia_promyelocytic-HL-606.3
Leukemialymphoblastic(MOLT-4)5.9
Liver11.35
Lung15.1
Lymphnode6
Lymphoma_burkitts(Daudi)9.65
Lymphoma_burkitts(Raji)10.8
MedullaOblongata6.8
OccipitalLobe6.45
OlfactoryBulb5.8
Ovary5.4
Pancreas5.85
PancreaticIslet7.65
ParietalLobe7.8
Pituitary8.6
Placenta7
Pons7.05
PrefrontalCortex9.15
Prostate8.3
Salivarygland5.85
SkeletalMuscle8.3
Skin5.85
SmoothMuscle8.35
Spinalcord7.6
SubthalamicNucleus7.95
SuperiorCervicalGanglion8.5
TemporalLobe7.2
Testis7.15
TestisGermCell6.55
TestisIntersitial6.6
TestisLeydigCell7.55
TestisSeminiferousTubule7.55
Thalamus7.45
Thymus6.55
Thyroid8.65
Tongue8.25
Tonsil10.8
Trachea6.35
TrigeminalGanglion7.05
Uterus5.85
UterusCorpus6.6
WholeBlood8.05
Wholebrain5.65
colon8
pineal_day8.68
pineal_night8.52
retina9.025
small_intestine7.3
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_15956_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.58 ± 0.73
Basal Forebrain3.19 ± 0.36
Basal Part of Pons3.09 ± 0.41
Cerebellar Cortex3.65 ± 0.44
Cerebellar Nuclei3.53 ± 0.55
Claustrum3.5 ± 0.74
Epithalamus3.37 ± 0.33
Frontal Lobe3.03 ± 0.59
Globus Pallidus3.37 ± 0.51
Hypothalamus3.08 ± 0.9
Insula3.36 ± 0.7
Limbic Lobe3.42 ± 0.63
Mesencephalon3.31 ± 0.69
Myelencephalon3.39 ± 0.65
Occipital Lobe3.85 ± 0.45
Parietal Lobe3.51 ± 0.55
Pontine Tegmentum3.52 ± 0.73
Striatum3 ± 0.6
Subthalamus3.27 ± 0.23
Temporal Lobe3.69 ± 0.54
Thalamus3.22 ± 0.64
White Matter4.59 ± 0.73
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mst1rCBCerebellum16.45
19.41
Mst1rCTXCerebral cortex9.3
8.07
Mst1rHIPHippocampal region2.84
2.74
Mst1rHPFHippocampal formation3.24
2.94
Mst1rHYHypothalamus1.11
1.06
Mst1rLSXLateral septal complex0.37
0.29
Mst1rMBMidbrain1.84
1.78
Mst1rMYMedulla2.62
2.83
Mst1rOLFOlfactory bulb11.35
8.59
Mst1rPPons0.97
1.14
Mst1rPALPallidum2.96
2.67
Mst1rRHPRetrohippocampal region3.82
3.02
Mst1rsAMYStriatum-like amygdalar nuclei5.2
3.79
Mst1rSTRStriatum2.9
2.22
Mst1rSTRdStriatum dorsal region1.5
1.15
Mst1rSTRvStriatum ventral region8.45
6.2
Mst1rTHThalamus0.98
0.88
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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