AutismKB 2.0

Annotation Detail for MSX1


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Basic Information Top
Gene Symbol:MSX1 ( HOX7,HYD1,STHAG1 )
Gene Full Name: msh homeobox 1
Band: 4p16.2
Quick LinksEntrez ID:4487; OMIM: 142983; Uniprot ID:MSX1_HUMAN; ENSEMBL ID: ENSG00000163132; HGNC ID: 7391
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst1 / 6231916
fetus12 / 56401221
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult27 / 193912113
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma4 / 10688337
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal41 / 336030712
ovarian tumor2 / 7668226
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor9 / 9025799
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone2 / 7165527
bone marrow0 / 488010 
brain14 / 110098912
cervix1 / 4817120
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue9 / 21572241
esophagus0 / 202090 
eye1 / 2110544
heart3 / 8962633
intestine2 / 2344728
kidney3 / 21177714
larynx0 / 241450 
liver1 / 2077434
lung6 / 33697417
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary2 / 10205119
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta4 / 28082514
prostate5 / 18934526
salivary gland0 / 201550 
skin1 / 2105744
spleen1 / 5395218
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus18 / 23287877
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205932_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.95
Adipocyte50.15
AdrenalCortex9.8
Adrenalgland6.25
Amygdala10.35
Appendix8.3
AtrioventricularNode7.55
BDCA4+_DentriticCells6.15
Bonemarrow7.75
BronchialEpithelialCells6.05
CD105+_Endothelial6.5
CD14+_Monocytes7.25
CD19+_BCells(neg._sel.)7.05
CD33+_Myeloid8.5
CD34+7.95
CD4+_Tcells6.3
CD56+_NKCells7.7
CD71+_EarlyErythroid6.8
CD8+_Tcells5.6
CardiacMyocytes11.95
Caudatenucleus6.35
Cerebellum5.9
CerebellumPeduncles9.75
CiliaryGanglion6.25
CingulateCortex7.3
Colorectaladenocarcinoma947
DorsalRootGanglion6.35
FetalThyroid10.45
Fetalbrain6.25
Fetalliver6.4
Fetallung6.1
GlobusPallidus5.8
Heart12.4
Hypothalamus7.75
Kidney6.55
Leukemia_chronicMyelogenousK-5627.3
Leukemia_promyelocytic-HL-605.9
Leukemialymphoblastic(MOLT-4)12.55
Liver10.75
Lung7.7
Lymphnode5.85
Lymphoma_burkitts(Daudi)8.5
Lymphoma_burkitts(Raji)10.5
MedullaOblongata6.25
OccipitalLobe7.05
OlfactoryBulb6.85
Ovary5.85
Pancreas6.3
PancreaticIslet8.35
ParietalLobe8.25
Pituitary34.4
Placenta7.3
Pons7.6
PrefrontalCortex10.15
Prostate8.8
Salivarygland5.8
SkeletalMuscle10.35
Skin7.9
SmoothMuscle9.3
Spinalcord8.3
SubthalamicNucleus6.9
SuperiorCervicalGanglion9.55
TemporalLobe6.7
Testis5.5
TestisGermCell5.2
TestisIntersitial5.9
TestisLeydigCell6.9
TestisSeminiferousTubule6.15
Thalamus8.05
Thymus5.5
Thyroid11.95
Tongue12.3
Tonsil7.1
Trachea5.15
TrigeminalGanglion9.65
Uterus105.85
UterusCorpus13.05
WholeBlood6.8
Wholebrain13.5
colon7
pineal_day14.38
pineal_night31.2
retina10.325
small_intestine6.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P345837
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.75 ± 0.78
Basal Forebrain4.43 ± 0.37
Basal Part of Pons4.74 ± 0.74
Cerebellar Cortex4.25 ± 0.57
Cerebellar Nuclei4.82 ± 0.44
Claustrum4.84 ± 0.81
Epithalamus4.64 ± 0.59
Frontal Lobe4.58 ± 0.66
Globus Pallidus5.36 ± 0.74
Hypothalamus4.03 ± 0.55
Insula4.67 ± 0.65
Limbic Lobe4.67 ± 0.68
Mesencephalon4.46 ± 0.6
Myelencephalon4.68 ± 0.69
Occipital Lobe4.54 ± 0.86
Parietal Lobe4.6 ± 0.66
Pontine Tegmentum4.52 ± 0.63
Striatum4.66 ± 0.63
Subthalamus4.1 ± 0.7
Temporal Lobe4.59 ± 0.69
Thalamus4.66 ± 0.64
White Matter4.6 ± 0.62
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Msx1CBCerebellum1.6
2.6
Msx1CTXCerebral cortex0.48
0.64
Msx1HIPHippocampal region0.52
0.85
Msx1HPFHippocampal formation1.9
2.45
Msx1HYHypothalamus0.41
0.33
Msx1LSXLateral septal complex0.37
0.47
Msx1MBMidbrain0.38
0.66
Msx1MYMedulla1.06
1.97
Msx1OLFOlfactory bulb1.23
1.36
Msx1PPons0.21
0.23
Msx1PALPallidum0.12
0.16
Msx1RHPRetrohippocampal region3.89
4.39
Msx1sAMYStriatum-like amygdalar nuclei0.07
0.1
Msx1STRStriatum0.23
0.32
Msx1STRdStriatum dorsal region0.24
0.29
Msx1STRvStriatum ventral region0.21
0.55
Msx1THThalamus1.15
1.78
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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