AutismKB 2.0

Annotation Detail for MT2A


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Basic Information Top
Gene Symbol:MT2A ( MT2 )
Gene Full Name: metallothionein 2A
Band: 16q13
Quick LinksEntrez ID:4502; OMIM: 156360; Uniprot ID:MT2_HUMAN; ENSEMBL ID: ENSG00000125148; HGNC ID: 7406
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst38 / 62319609
fetus32 / 56401256
neonate4 / 31097128
infant3 / 23620127
juvenile0 / 555560 
adult222 / 1939121114
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma0 / 174750 
breast (mammary gland) tumor23 / 94178244
cervical tumor1 / 3436629
chondrosarcoma14 / 82823169
colorectal tumor2 / 11424617
esophageal tumor1 / 1729057
gastrointestinal tumor8 / 11936967
germ cell tumor4 / 26384515
glioma23 / 106883215
head and neck tumor5 / 13630236
kidney tumor15 / 68959217
leukemia6 / 9584262
liver tumor14 / 96359145
lung tumor4 / 10312738
lymphoma0 / 717550 
non-neoplasia13 / 97250133
normal434 / 3360307129
ovarian tumor1 / 7668213
pancreatic tumor14 / 104616133
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer8 / 10268077
retinoblastoma0 / 463560 
skin tumor5 / 12494940
soft tissue/muscle tissue tumor20 / 125191159
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue4 / 13106305
adrenal gland9 / 33197271
ascites2 / 4001549
bladder0 / 297570 
blood3 / 12347824
bone8 / 71655111
bone marrow8 / 48801163
brain49 / 110098944
cervix2 / 4817141
connective tissue35 / 149255234
ear0 / 162120 
embryonic tissue64 / 215722296
esophagus1 / 2020949
eye31 / 211054146
heart17 / 89626189
intestine22 / 23447293
kidney20 / 21177794
larynx0 / 241450 
liver130 / 207743625
lung19 / 33697456
lymph0 / 442700 
lymph node4 / 9161043
mammary gland24 / 153271156
mouth2 / 6705229
muscle26 / 107715241
nerve1 / 1576863
ovary6 / 10205158
pancreas17 / 21481279
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta12 / 28082542
prostate30 / 189345158
salivary gland1 / 2015549
skin17 / 21057480
spleen0 / 539520 
stomach10 / 96619103
testis2 / 3304426
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord4 / 13680292
uterus20 / 23287885
vascular15 / 51780289
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 212185_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts379.65
Adipocyte13580.7
AdrenalCortex19769.8
Adrenalgland11064.75
Amygdala3348.75
Appendix2284.75
AtrioventricularNode6151.35
BDCA4+_DentriticCells570.9
Bonemarrow493.8
BronchialEpithelialCells27917.6
CD105+_Endothelial613.9
CD14+_Monocytes1171.4
CD19+_BCells(neg._sel.)367.8
CD33+_Myeloid684.15
CD34+767.6
CD4+_Tcells1425.1
CD56+_NKCells1790.3
CD71+_EarlyErythroid238.8
CD8+_Tcells1496.25
CardiacMyocytes3567.55
Caudatenucleus3028.85
Cerebellum886.45
CerebellumPeduncles1778.35
CiliaryGanglion5034.45
CingulateCortex3175.75
Colorectaladenocarcinoma6321.25
DorsalRootGanglion3963.4
FetalThyroid10506.65
Fetalbrain1478.9
Fetalliver12592.85
Fetallung11015.65
GlobusPallidus2079.6
Heart5169.35
Hypothalamus5937.8
Kidney11384.05
Leukemia_chronicMyelogenousK-562404.65
Leukemia_promyelocytic-HL-60611.95
Leukemialymphoblastic(MOLT-4)737.4
Liver26233.55
Lung9090.45
Lymphnode935.95
Lymphoma_burkitts(Daudi)1547.6
Lymphoma_burkitts(Raji)2811.05
MedullaOblongata1766.55
OccipitalLobe2240.8
OlfactoryBulb8117.9
Ovary3996.95
Pancreas5715.3
PancreaticIslet9942.1
ParietalLobe2050.7
Pituitary1636.55
Placenta1555.2
Pons5625.65
PrefrontalCortex6181.45
Prostate5505.2
Salivarygland1829.05
SkeletalMuscle12168.25
Skin4083.45
SmoothMuscle10524.15
Spinalcord5658.45
SubthalamicNucleus5348.75
SuperiorCervicalGanglion1043.15
TemporalLobe4766.75
Testis718.65
TestisGermCell712.9
TestisIntersitial245.4
TestisLeydigCell904.05
TestisSeminiferousTubule888.6
Thalamus5006.9
Thymus1462.1
Thyroid12185.15
Tongue3690.9
Tonsil854.8
Trachea1352.25
TrigeminalGanglion3773.75
Uterus1599.65
UterusCorpus9087.35
WholeBlood1103.2
Wholebrain4362.65
colon671.7
pineal_day2485.34
pineal_night1734.18
retina8414.375
small_intestine1228.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P361896
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala13.04 ± 0.31
Basal Forebrain12.98 ± 0.23
Basal Part of Pons11.98 ± 0.29
Cerebellar Cortex12.2 ± 0.25
Cerebellar Nuclei13 ± 0.52
Claustrum12.37 ± 0.42
Epithalamus13.2 ± 0.18
Frontal Lobe12.68 ± 0.41
Globus Pallidus14.15 ± 0.44
Hypothalamus12.73 ± 0.49
Insula12.9 ± 0.37
Limbic Lobe12.59 ± 0.63
Mesencephalon13.1 ± 0.53
Myelencephalon12.85 ± 0.5
Occipital Lobe12.81 ± 0.43
Parietal Lobe12.84 ± 0.54
Pontine Tegmentum13.19 ± 0.39
Striatum13.73 ± 0.42
Subthalamus12.72 ± 0.14
Temporal Lobe12.69 ± 0.38
Thalamus13.12 ± 0.43
White Matter12.48 ± 0.52
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
MT2_HUMAN_0 0 0 0 MDPNCSCAAGDSCTCAGSCK PRIDE
PAp00009409 8 44 51 CAQGCICK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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