AutismKB 2.0

Annotation Detail for MTF1


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Basic Information Top
Gene Symbol:MTF1 ( MGC23036,MTF-1,ZRF )
Gene Full Name: metal-regulatory transcription factor 1
Band: 1p34.3
Quick LinksEntrez ID:4520; OMIM: 600172; Uniprot ID:MTF1_HUMAN; ENSEMBL ID: ENSG00000188786; HGNC ID: 7428
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus40 / 56401270
neonate1 / 3109732
infant0 / 236200 
juvenile1 / 5555617
adult66 / 193912134
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor4 / 34366116
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor1 / 1729057
gastrointestinal tumor3 / 11936925
germ cell tumor10 / 26384537
glioma3 / 10688328
head and neck tumor2 / 13630214
kidney tumor3 / 6895943
leukemia7 / 9584273
liver tumor2 / 9635920
lung tumor2 / 10312719
lymphoma2 / 7175527
non-neoplasia3 / 9725030
normal160 / 336030747
ovarian tumor1 / 7668213
pancreatic tumor2 / 10461619
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood9 / 12347872
bone1 / 7165513
bone marrow2 / 4880140
brain28 / 110098925
cervix4 / 4817183
connective tissue2 / 14925513
ear0 / 162120 
embryonic tissue2 / 2157229
esophagus1 / 2020949
eye14 / 21105466
heart2 / 8962622
intestine4 / 23447217
kidney14 / 21177766
larynx0 / 241450 
liver5 / 20774324
lung30 / 33697489
lymph1 / 4427022
lymph node5 / 9161054
mammary gland8 / 15327152
mouth2 / 6705229
muscle5 / 10771546
nerve1 / 1576863
ovary2 / 10205119
pancreas13 / 21481260
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta2 / 2808257
prostate2 / 18934510
salivary gland0 / 201550 
skin8 / 21057437
spleen3 / 5395255
stomach4 / 9661941
testis16 / 33044248
thymus3 / 8113136
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus4 / 23287817
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205323_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts8.4
Adipocyte6.65
AdrenalCortex9.75
Adrenalgland5.5
Amygdala6.5
Appendix13.9
AtrioventricularNode6.35
BDCA4+_DentriticCells7.95
Bonemarrow6.4
BronchialEpithelialCells6.05
CD105+_Endothelial7.6
CD14+_Monocytes8.4
CD19+_BCells(neg._sel.)7.1
CD33+_Myeloid44.75
CD34+11.5
CD4+_Tcells8
CD56+_NKCells8.05
CD71+_EarlyErythroid6.05
CD8+_Tcells10.15
CardiacMyocytes8.1
Caudatenucleus5.75
Cerebellum5.2
CerebellumPeduncles7.4
CiliaryGanglion5
CingulateCortex6.7
Colorectaladenocarcinoma6.6
DorsalRootGanglion4.95
FetalThyroid6.4
Fetalbrain6.35
Fetalliver5.55
Fetallung4.95
GlobusPallidus4.7
Heart8.2
Hypothalamus6.45
Kidney5.15
Leukemia_chronicMyelogenousK-5625.8
Leukemia_promyelocytic-HL-605.75
Leukemialymphoblastic(MOLT-4)5.45
Liver8.55
Lung6.6
Lymphnode5.55
Lymphoma_burkitts(Daudi)8.35
Lymphoma_burkitts(Raji)9.1
MedullaOblongata5.9
OccipitalLobe5.75
OlfactoryBulb6.5
Ovary5.45
Pancreas5.1
PancreaticIslet6.85
ParietalLobe6.65
Pituitary10.25
Placenta7.55
Pons6.15
PrefrontalCortex8.2
Prostate7.65
Salivarygland5.15
SkeletalMuscle9.55
Skin5.4
SmoothMuscle7.65
Spinalcord6.6
SubthalamicNucleus5.8
SuperiorCervicalGanglion7.65
TemporalLobe5.7
Testis5.6
TestisGermCell6.35
TestisIntersitial5.65
TestisLeydigCell6.45
TestisSeminiferousTubule7.5
Thalamus6.45
Thymus5.35
Thyroid8.1
Tongue6.35
Tonsil6.4
Trachea5.45
TrigeminalGanglion6.5
Uterus6.3
UterusCorpus6.95
WholeBlood8.05
Wholebrain4.6
colon6.6
pineal_day8.82
pineal_night9.72
retina8.15
small_intestine6.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P932579
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.95 ± 0.94
Basal Forebrain2.26 ± 0.35
Basal Part of Pons2.18 ± 0.35
Cerebellar Cortex2.49 ± 0.69
Cerebellar Nuclei2.68 ± 0.72
Claustrum3.18 ± 0.77
Epithalamus2.56 ± 0.55
Frontal Lobe2.27 ± 0.59
Globus Pallidus3.04 ± 0.61
Hypothalamus2.32 ± 0.66
Insula2.2 ± 0.5
Limbic Lobe2.53 ± 0.61
Mesencephalon2.65 ± 0.65
Myelencephalon2.53 ± 0.61
Occipital Lobe2.75 ± 0.62
Parietal Lobe2.64 ± 0.59
Pontine Tegmentum2.54 ± 0.65
Striatum2.67 ± 0.7
Subthalamus2.64 ± 0.69
Temporal Lobe2.34 ± 0.59
Thalamus2.45 ± 0.58
White Matter3.46 ± 0.68
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Mtf1CBCerebellum29.14
22.56
Mtf1CTXCerebral cortex19.96
11.1
Mtf1HIPHippocampal region34.16
16.97
Mtf1HPFHippocampal formation35.4
18.92
Mtf1HYHypothalamus9.07
5.42
Mtf1LSXLateral septal complex0.83
0.53
Mtf1MBMidbrain8.19
5.6
Mtf1MYMedulla28.23
21.55
Mtf1OLFOlfactory bulb31.16
16.93
Mtf1PPons17.68
13.35
Mtf1PALPallidum4.45
2.97
Mtf1RHPRetrohippocampal region38.03
21.61
Mtf1sAMYStriatum-like amygdalar nuclei14.9
8.44
Mtf1STRStriatum6.07
3.27
Mtf1STRdStriatum dorsal region3.59
1.85
Mtf1STRvStriatum ventral region14.69
7.33
Mtf1THThalamus6.7
4.04
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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