AutismKB 2.0

Annotation Detail for MTR


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Basic Information Top
Gene Symbol:MTR ( FLJ33168,FLJ43216,FLJ45386,MS,cblG )
Gene Full Name: 5-methyltetrahydrofolate-homocysteine methyltransferase
Band: 1q43
Quick LinksEntrez ID:4548; OMIM: 156570; Uniprot ID:METH_HUMAN; ENSEMBL ID: ENSG00000116984; HGNC ID: 7468
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst2 / 6231932
fetus44 / 56401278
neonate0 / 310970 
infant2 / 2362084
juvenile6 / 55556107
adult104 / 193912153
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor3 / 3436687
chondrosarcoma7 / 8282384
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor3 / 11936925
germ cell tumor9 / 26384534
glioma2 / 10688318
head and neck tumor6 / 13630244
kidney tumor2 / 6895929
leukemia4 / 9584241
liver tumor1 / 9635910
lung tumor3 / 10312729
lymphoma1 / 7175513
non-neoplasia1 / 9725010
normal201 / 336030759
ovarian tumor1 / 7668213
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS7 / 12568055
prostate cancer4 / 10268038
retinoblastoma3 / 4635664
skin tumor2 / 12494916
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland5 / 33197150
ascites0 / 400150 
bladder0 / 297570 
blood3 / 12347824
bone5 / 7165569
bone marrow1 / 4880120
brain40 / 110098936
cervix3 / 4817162
connective tissue5 / 14925533
ear2 / 16212123
embryonic tissue9 / 21572241
esophagus0 / 202090 
eye5 / 21105423
heart6 / 8962666
intestine11 / 23447246
kidney19 / 21177789
larynx1 / 2414541
liver10 / 20774348
lung27 / 33697480
lymph1 / 4427022
lymph node7 / 9161076
mammary gland10 / 15327165
mouth8 / 67052119
muscle6 / 10771555
nerve1 / 1576863
ovary1 / 1020519
pancreas8 / 21481237
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta10 / 28082535
prostate5 / 18934526
salivary gland0 / 201550 
skin19 / 21057490
spleen2 / 5395237
stomach12 / 96619124
testis9 / 33044227
thymus2 / 8113124
thyroid3 / 4747363
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus11 / 23287847
vascular6 / 51780115
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203774_at
Cell line Expression level Expression bar
721_B_lymphoblasts160.55
Adipocyte16.25
AdrenalCortex21.3
Adrenalgland12.85
Amygdala14.35
Appendix20.15
AtrioventricularNode14.75
BDCA4+_DentriticCells81.05
Bonemarrow14.95
BronchialEpithelialCells13.1
CD105+_Endothelial186.8
CD14+_Monocytes26.2
CD19+_BCells(neg._sel.)57.75
CD33+_Myeloid45.15
CD34+216.55
CD4+_Tcells72.1
CD56+_NKCells86.05
CD71+_EarlyErythroid14.8
CD8+_Tcells107.75
CardiacMyocytes39.85
Caudatenucleus13.55
Cerebellum11
CerebellumPeduncles18.4
CiliaryGanglion16.15
CingulateCortex14.9
Colorectaladenocarcinoma14.2
DorsalRootGanglion14.5
FetalThyroid29.65
Fetalbrain11.8
Fetalliver22.35
Fetallung10.7
GlobusPallidus12.25
Heart20.5
Hypothalamus18.05
Kidney13.3
Leukemia_chronicMyelogenousK-56241.25
Leukemia_promyelocytic-HL-6051.7
Leukemialymphoblastic(MOLT-4)27.55
Liver22.4
Lung13.4
Lymphnode18.45
Lymphoma_burkitts(Daudi)19.65
Lymphoma_burkitts(Raji)23.6
MedullaOblongata19.75
OccipitalLobe13.15
OlfactoryBulb16.2
Ovary15.35
Pancreas13.3
PancreaticIslet17.15
ParietalLobe16
Pituitary15.2
Placenta13
Pons14.2
PrefrontalCortex15.2
Prostate15.8
Salivarygland11.85
SkeletalMuscle24.2
Skin16.2
SmoothMuscle18.8
Spinalcord16.3
SubthalamicNucleus14.25
SuperiorCervicalGanglion23.75
TemporalLobe13.9
Testis11.6
TestisGermCell30.7
TestisIntersitial16.85
TestisLeydigCell26.55
TestisSeminiferousTubule29.55
Thalamus14.05
Thymus10.2
Thyroid104.6
Tongue19.7
Tonsil22.25
Trachea11.15
TrigeminalGanglion24.15
Uterus63.45
UterusCorpus17.95
WholeBlood16.25
Wholebrain12.15
colon16.9
pineal_day28.76
pineal_night35.2
retina20.5
small_intestine14.4
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P67806
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.55 ± 0.34
Basal Forebrain4.31 ± 0.42
Basal Part of Pons4.23 ± 0.51
Cerebellar Cortex4.51 ± 0.49
Cerebellar Nuclei4.12 ± 0.35
Claustrum3.97 ± 0.71
Epithalamus4.19 ± 0.5
Frontal Lobe4.34 ± 0.51
Globus Pallidus4.31 ± 0.48
Hypothalamus4.34 ± 0.43
Insula4.55 ± 0.37
Limbic Lobe4.43 ± 0.47
Mesencephalon4.37 ± 0.5
Myelencephalon4.33 ± 0.5
Occipital Lobe4.68 ± 0.38
Parietal Lobe4.4 ± 0.44
Pontine Tegmentum4.43 ± 0.51
Striatum4.2 ± 0.52
Subthalamus4.39 ± 0.4
Temporal Lobe4.42 ± 0.46
Thalamus4.16 ± 0.5
White Matter4.63 ± 0.64
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00024747 23 1072 1094 DSASTEPYYCLSDFIAPLHSGIR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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