AutismKB 2.0

Annotation Detail for TRIM37


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Basic Information Top
Gene Symbol:TRIM37 ( KIAA0898,MUL,POB1,TEF3 )
Gene Full Name: tripartite motif-containing 37
Band: 17q22
Quick LinksEntrez ID:4591; OMIM: 605073; Uniprot ID:TRI37_HUMAN; ENSEMBL ID: ENSG00000108395; HGNC ID: 7523
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body7 / 7076198
blastocyst4 / 6231964
fetus21 / 56401237
neonate0 / 310970 
infant0 / 236200 
juvenile5 / 5555689
adult75 / 193912138
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor5 / 9417853
cervical tumor0 / 343660 
chondrosarcoma7 / 8282384
colorectal tumor4 / 11424635
esophageal tumor2 / 17290115
gastrointestinal tumor0 / 1193690 
germ cell tumor10 / 26384537
glioma4 / 10688337
head and neck tumor7 / 13630251
kidney tumor6 / 6895987
leukemia1 / 9584210
liver tumor7 / 9635972
lung tumor3 / 10312729
lymphoma5 / 7175569
non-neoplasia0 / 972500 
normal229 / 336030768
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer0 / 1026800 
retinoblastoma7 / 46356151
skin tumor4 / 12494932
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood2 / 12347816
bone4 / 7165555
bone marrow1 / 4880120
brain152 / 1100989138
cervix0 / 481710 
connective tissue10 / 14925566
ear0 / 162120 
embryonic tissue14 / 21572264
esophagus2 / 2020998
eye11 / 21105452
heart2 / 8962622
intestine9 / 23447238
kidney11 / 21177751
larynx0 / 241450 
liver9 / 20774343
lung8 / 33697423
lymph1 / 4427022
lymph node1 / 9161010
mammary gland9 / 15327158
mouth4 / 6705259
muscle3 / 10771527
nerve0 / 157680 
ovary1 / 1020519
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta8 / 28082528
prostate0 / 1893450 
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach0 / 966190 
testis70 / 330442211
thymus3 / 8113136
thyroid3 / 4747363
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus9 / 23287838
vascular0 / 517800 
Microarray in BioGPS Top
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  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213009_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts63.95
Adipocyte10.95
AdrenalCortex6.75
Adrenalgland9.05
Amygdala617.55
Appendix10.8
AtrioventricularNode5.1
BDCA4+_DentriticCells23.95
Bonemarrow8.25
BronchialEpithelialCells41.95
CD105+_Endothelial70.7
CD14+_Monocytes14.4
CD19+_BCells(neg._sel.)37.1
CD33+_Myeloid21.55
CD34+114.3
CD4+_Tcells77.15
CD56+_NKCells43.9
CD71+_EarlyErythroid10.9
CD8+_Tcells63.95
CardiacMyocytes63.3
Caudatenucleus153.7
Cerebellum117
CerebellumPeduncles172.6
CiliaryGanglion5.45
CingulateCortex368.3
Colorectaladenocarcinoma46
DorsalRootGanglion6.1
FetalThyroid13.6
Fetalbrain324.3
Fetalliver10.05
Fetallung17.5
GlobusPallidus133.3
Heart11.15
Hypothalamus465.75
Kidney6.65
Leukemia_chronicMyelogenousK-56248.6
Leukemia_promyelocytic-HL-6094.55
Leukemialymphoblastic(MOLT-4)59.05
Liver10.9
Lung9.2
Lymphnode13.8
Lymphoma_burkitts(Daudi)25.85
Lymphoma_burkitts(Raji)79.35
MedullaOblongata320.55
OccipitalLobe371.4
OlfactoryBulb9.65
Ovary5.6
Pancreas7.05
PancreaticIslet18.95
ParietalLobe226.6
Pituitary61.2
Placenta20.75
Pons118.1
PrefrontalCortex1097.4
Prostate23.55
Salivarygland7.15
SkeletalMuscle6.85
Skin6.3
SmoothMuscle221.9
Spinalcord67.9
SubthalamicNucleus321.75
SuperiorCervicalGanglion14.9
TemporalLobe272
Testis101.85
TestisGermCell242
TestisIntersitial106.7
TestisLeydigCell80.5
TestisSeminiferousTubule113.35
Thalamus466.05
Thymus13.6
Thyroid51.35
Tongue7.1
Tonsil8.65
Trachea10.5
TrigeminalGanglion8.55
Uterus34.2
UterusCorpus5.3
WholeBlood24.75
Wholebrain301.6
colon16.75
pineal_day76.98
pineal_night88.48
retina73.125
small_intestine26.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P21230
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.61 ± 0.56
Basal Forebrain7.58 ± 0.26
Basal Part of Pons8.9 ± 0.16
Cerebellar Cortex8.24 ± 0.24
Cerebellar Nuclei8.18 ± 0.59
Claustrum8.34 ± 0.48
Epithalamus7.51 ± 0.44
Frontal Lobe8.29 ± 0.39
Globus Pallidus6.98 ± 0.52
Hypothalamus8.09 ± 0.44
Insula8.22 ± 0.24
Limbic Lobe8.02 ± 0.53
Mesencephalon7.87 ± 0.49
Myelencephalon8 ± 0.65
Occipital Lobe7.73 ± 0.66
Parietal Lobe8.32 ± 0.43
Pontine Tegmentum7.96 ± 0.42
Striatum7.1 ± 0.53
Subthalamus8.93 ± 0.1
Temporal Lobe8.3 ± 0.33
Thalamus8.18 ± 0.39
White Matter6.34 ± 0.4
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Trim37CBCerebellum27.95
41.59
Trim37CTXCerebral cortex74.69
61.57
Trim37HIPHippocampal region28.9
36.36
Trim37HPFHippocampal formation37.02
38.94
Trim37HYHypothalamus6.72
6.22
Trim37LSXLateral septal complex5.5
4.52
Trim37MBMidbrain28.79
28.86
Trim37MYMedulla37.49
48.36
Trim37OLFOlfactory bulb30.49
24.22
Trim37PPons33.05
41.55
Trim37PALPallidum12.27
12.2
Trim37RHPRetrohippocampal region53.18
44.81
Trim37sAMYStriatum-like amygdalar nuclei19.88
13.71
Trim37STRStriatum18.03
13.28
Trim37STRdStriatum dorsal region20.7
15.5
Trim37STRvStriatum ventral region15.02
10.63
Trim37THThalamus30.78
29.09
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018