AutismKB 2.0

Annotation Detail for ASTN1


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Basic Information Top
Gene Symbol:ASTN1 ( ASTN,KIAA1747 )
Gene Full Name: astrotactin 1
Band: 1q25.2
Quick LinksEntrez ID:460; OMIM: 600904; Uniprot ID:ASTN1_HUMAN; ENSEMBL ID: ENSG00000152092; HGNC ID: 773
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus25 / 56401244
neonate0 / 310970 
infant3 / 23620127
juvenile2 / 5555635
adult43 / 193912122
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor13 / 26384549
glioma8 / 10688374
head and neck tumor1 / 1363027
kidney tumor2 / 6895929
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia3 / 9725030
normal125 / 336030737
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland3 / 3319790
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain88 / 110098979
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye18 / 21105485
heart2 / 8962622
intestine0 / 2344720 
kidney2 / 2117779
larynx1 / 2414541
liver0 / 2077430 
lung9 / 33697426
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle4 / 10771537
nerve2 / 15768126
ovary2 / 10205119
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis12 / 33044236
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213197_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.55
Adipocyte4.55
AdrenalCortex8
Adrenalgland7.4
Amygdala357.05
Appendix4.85
AtrioventricularNode3.8
BDCA4+_DentriticCells4.95
Bonemarrow4.6
BronchialEpithelialCells4.45
CD105+_Endothelial4.65
CD14+_Monocytes4.85
CD19+_BCells(neg._sel.)5.65
CD33+_Myeloid5.75
CD34+5.7
CD4+_Tcells4.85
CD56+_NKCells5.3
CD71+_EarlyErythroid4.35
CD8+_Tcells4.4
CardiacMyocytes6.15
Caudatenucleus57.75
Cerebellum23.35
CerebellumPeduncles13.35
CiliaryGanglion3.45
CingulateCortex40.45
Colorectaladenocarcinoma4.65
DorsalRootGanglion4.7
FetalThyroid4.55
Fetalbrain282.45
Fetalliver4.05
Fetallung3.65
GlobusPallidus35.5
Heart6.3
Hypothalamus140.4
Kidney3.9
Leukemia_chronicMyelogenousK-5624.15
Leukemia_promyelocytic-HL-604.1
Leukemialymphoblastic(MOLT-4)3.7
Liver6.3
Lung5
Lymphnode3.9
Lymphoma_burkitts(Daudi)6.05
Lymphoma_burkitts(Raji)6.7
MedullaOblongata45.2
OccipitalLobe129.8
OlfactoryBulb3.75
Ovary3.35
Pancreas3.85
PancreaticIslet5
ParietalLobe27.25
Pituitary8.95
Placenta4.65
Pons18
PrefrontalCortex140.45
Prostate5.35
Salivarygland3.75
SkeletalMuscle5.7
Skin5.75
SmoothMuscle5.2
Spinalcord21.45
SubthalamicNucleus67.5
SuperiorCervicalGanglion5.75
TemporalLobe12.1
Testis3.9
TestisGermCell3.9
TestisIntersitial3.9
TestisLeydigCell4.6
TestisSeminiferousTubule3.95
Thalamus60.45
Thymus3.6
Thyroid5.7
Tongue5.55
Tonsil4.55
Trachea3.9
TrigeminalGanglion4.9
Uterus3.75
UterusCorpus4.2
WholeBlood5
Wholebrain201.4
colon4.65
pineal_day172.62
pineal_night128.06
retina19.3
small_intestine4.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_975_PI416379584
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala7.45 ± 0.24
Basal Forebrain7.27 ± 0.3
Basal Part of Pons7.2 ± 0.22
Cerebellar Cortex7.04 ± 0.11
Cerebellar Nuclei6.98 ± 0.13
Claustrum7.36 ± 0.27
Epithalamus7.12 ± 0.39
Frontal Lobe7.38 ± 0.26
Globus Pallidus7.32 ± 0.25
Hypothalamus7.47 ± 0.13
Insula7.52 ± 0.16
Limbic Lobe7.44 ± 0.31
Mesencephalon7.32 ± 0.29
Myelencephalon7.31 ± 0.31
Occipital Lobe7.09 ± 0.26
Parietal Lobe7.3 ± 0.27
Pontine Tegmentum7.26 ± 0.28
Striatum7.21 ± 0.4
Subthalamus7.1 ± 0.01
Temporal Lobe7.46 ± 0.23
Thalamus7.35 ± 0.21
White Matter6.33 ± 0.11
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Astn1CBCerebellum30.4
72.66
Astn1CTXCerebral cortex100
100
Astn1HIPHippocampal region100
100
Astn1HPFHippocampal formation100
100
Astn1HYHypothalamus100
100
Astn1LSXLateral septal complex100
100
Astn1MBMidbrain100
95.4
Astn1MYMedulla70.39
57.54
Astn1OLFOlfactory bulb100
100
Astn1PPons80.19
62.63
Astn1PALPallidum100
100
Astn1RHPRetrohippocampal region100
100
Astn1sAMYStriatum-like amygdalar nuclei100
100
Astn1STRStriatum100
92.34
Astn1STRdStriatum dorsal region100
75.93
Astn1STRvStriatum ventral region100
98.24
Astn1THThalamus100
93.68
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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