AutismKB 2.0

Annotation Detail for MYB


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Basic Information Top
Gene Symbol:MYB ( Cmyb,c-myb,c-myb_CDS,efg )
Gene Full Name: v-myb myeloblastosis viral oncogene homolog (avian)
Band: 6q23.3
Quick LinksEntrez ID:4602; OMIM: 189990; Uniprot ID:MYB_HUMAN; ENSEMBL ID: ENSG00000118513; HGNC ID: 7545
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus14 / 56401224
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult23 / 193912111
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor8 / 9417884
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor10 / 11424687
esophageal tumor0 / 172900 
gastrointestinal tumor1 / 1193698
germ cell tumor17 / 26384564
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia13 / 95842135
liver tumor1 / 9635910
lung tumor0 / 1031270 
lymphoma4 / 7175555
non-neoplasia0 / 972500 
normal27 / 33603078
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood4 / 12347832
bone0 / 716550 
bone marrow6 / 48801122
brain0 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye5 / 21105423
heart1 / 8962611
intestine14 / 23447259
kidney1 / 2117774
larynx0 / 241450 
liver4 / 20774319
lung3 / 3369748
lymph0 / 442700 
lymph node6 / 9161065
mammary gland11 / 15327171
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate3 / 18934515
salivary gland5 / 20155248
skin1 / 2105744
spleen0 / 539520 
stomach1 / 9661910
testis8 / 33044224
thymus3 / 8113136
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204798_at
Cell line Expression level Expression bar
721_B_lymphoblasts18.35
Adipocyte5.4
AdrenalCortex5.65
Adrenalgland4.55
Amygdala5.6
Appendix5.85
AtrioventricularNode4.45
BDCA4+_DentriticCells36.85
Bonemarrow36.3
BronchialEpithelialCells5.1
CD105+_Endothelial393.8
CD14+_Monocytes5.9
CD19+_BCells(neg._sel.)7.15
CD33+_Myeloid66
CD34+2026.5
CD4+_Tcells7.05
CD56+_NKCells6.45
CD71+_EarlyErythroid9.8
CD8+_Tcells5.65
CardiacMyocytes6.9
Caudatenucleus4.9
Cerebellum4.4
CerebellumPeduncles6.15
CiliaryGanglion4.05
CingulateCortex5.55
Colorectaladenocarcinoma5.45
DorsalRootGanglion4.4
FetalThyroid5.3
Fetalbrain5.4
Fetalliver6.3
Fetallung4.6
GlobusPallidus4.05
Heart6.9
Hypothalamus5.8
Kidney4.4
Leukemia_chronicMyelogenousK-56243.1
Leukemia_promyelocytic-HL-6011.2
Leukemialymphoblastic(MOLT-4)1010.5
Liver7.15
Lung6
Lymphnode4.65
Lymphoma_burkitts(Daudi)7.1
Lymphoma_burkitts(Raji)7.65
MedullaOblongata5
OccipitalLobe4.8
OlfactoryBulb4.3
Ovary3.7
Pancreas4.35
PancreaticIslet5.8
ParietalLobe5.8
Pituitary6.3
Placenta5.45
Pons5.15
PrefrontalCortex6.65
Prostate6.35
Salivarygland4.4
SkeletalMuscle6.65
Skin4.5
SmoothMuscle6.15
Spinalcord5.75
SubthalamicNucleus4.95
SuperiorCervicalGanglion6.5
TemporalLobe4.95
Testis4.6
TestisGermCell4.45
TestisIntersitial4.55
TestisLeydigCell5.4
TestisSeminiferousTubule4.6
Thalamus5.55
Thymus129
Thyroid6.55
Tongue5.4
Tonsil5.3
Trachea4.5
TrigeminalGanglion6.15
Uterus4.45
UterusCorpus4.9
WholeBlood6.1
Wholebrain4.55
colon9.65
pineal_day6.56
pineal_night6.46
retina6.5
small_intestine7.45
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P31073
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.49 ± 1.01
Basal Forebrain5.54 ± 1.07
Basal Part of Pons3.53 ± 0.41
Cerebellar Cortex3.07 ± 0.55
Cerebellar Nuclei3.25 ± 0.62
Claustrum3.31 ± 1.18
Epithalamus6.94 ± 1.86
Frontal Lobe4.26 ± 1.02
Globus Pallidus2.64 ± 1.5
Hypothalamus4.15 ± 1.14
Insula4.86 ± 0.41
Limbic Lobe4.28 ± 1.07
Mesencephalon4.22 ± 1.31
Myelencephalon4.25 ± 1.32
Occipital Lobe3.05 ± 1.69
Parietal Lobe4.07 ± 0.92
Pontine Tegmentum4.1 ± 1.01
Striatum7.33 ± 0.76
Subthalamus3.24 ± 0.71
Temporal Lobe4.66 ± 0.9
Thalamus3.47 ± 0.88
White Matter1.72 ± 1.33
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
MybCBCerebellum16.4
14.3
MybCTXCerebral cortex12.96
8.74
MybHIPHippocampal region11.16
5.51
MybHPFHippocampal formation10.43
5.43
MybHYHypothalamus1.62
0.96
MybLSXLateral septal complex1.68
1.02
MybMBMidbrain4.24
3.35
MybMYMedulla16.26
14.49
MybOLFOlfactory bulb12.05
7.99
MybPPons9.79
8.18
MybPALPallidum1.02
0.65
MybRHPRetrohippocampal region9
5.42
MybsAMYStriatum-like amygdalar nuclei0.58
0.28
MybSTRStriatum0.77
0.42
MybSTRdStriatum dorsal region0.56
0.32
MybSTRvStriatum ventral region0.99
0.46
MybTHThalamus2.39
1.57
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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