AutismKB 2.0

Annotation Detail for MYH4


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:MYH4 ( MYH2B,MyHC-2B,MyHC-IIb )
Gene Full Name: myosin, heavy chain 4, skeletal muscle
Band: 17p13.1
Quick LinksEntrez ID:4622; OMIM: 160742; Uniprot ID:MYH4_HUMAN; ENSEMBL ID: ENSG00000141048; HGNC ID: 7574
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus0 / 5640120 
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult1 / 19391210 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal1 / 33603070 
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye0 / 2110540 
heart0 / 896260 
intestine0 / 2344720 
kidney0 / 2117770 
larynx0 / 241450 
liver0 / 2077430 
lung0 / 3369740 
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate0 / 1893450 
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 208148_at
Cell line Expression level Expression bar
721_B_lymphoblasts10.6
Adipocyte11.75
AdrenalCortex20.75
Adrenalgland11.45
Amygdala10.4
Appendix22.7
AtrioventricularNode22.65
BDCA4+_DentriticCells9.75
Bonemarrow16.65
BronchialEpithelialCells10.25
CD105+_Endothelial11.5
CD14+_Monocytes12.9
CD19+_BCells(neg._sel.)12.8
CD33+_Myeloid12.8
CD34+12.45
CD4+_Tcells10.2
CD56+_NKCells11.45
CD71+_EarlyErythroid11.4
CD8+_Tcells8.5
CardiacMyocytes29.75
Caudatenucleus10.3
Cerebellum9.75
CerebellumPeduncles17.35
CiliaryGanglion22.95
CingulateCortex12.4
Colorectaladenocarcinoma10.75
DorsalRootGanglion16.1
FetalThyroid15.8
Fetalbrain11.2
Fetalliver10.7
Fetallung7.85
GlobusPallidus11.65
Heart49
Hypothalamus10.45
Kidney12.9
Leukemia_chronicMyelogenousK-56210
Leukemia_promyelocytic-HL-609.95
Leukemialymphoblastic(MOLT-4)8.2
Liver24.45
Lung12.3
Lymphnode8.55
Lymphoma_burkitts(Daudi)16.65
Lymphoma_burkitts(Raji)20.5
MedullaOblongata9.35
OccipitalLobe10.05
OlfactoryBulb8.5
Ovary15.35
Pancreas10.3
PancreaticIslet12.45
ParietalLobe14.6
Pituitary13.95
Placenta11.45
Pons13.75
PrefrontalCortex13.85
Prostate13.15
Salivarygland10.5
SkeletalMuscle33.4
Skin14
SmoothMuscle13.5
Spinalcord11.6
SubthalamicNucleus12.1
SuperiorCervicalGanglion23.1
TemporalLobe11.9
Testis10.4
TestisGermCell8.5
TestisIntersitial10.1
TestisLeydigCell14.3
TestisSeminiferousTubule9.9
Thalamus12.7
Thymus8.35
Thyroid13.05
Tongue22.55
Tonsil13.25
Trachea9.2
TrigeminalGanglion23.25
Uterus8.25
UterusCorpus16.85
WholeBlood12.2
Wholebrain7.8
colon10.9
pineal_day12.96
pineal_night12.74
retina13.925
small_intestine10.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_2413_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.38 ± 1.05
Basal Forebrain1.89 ± 0.29
Basal Part of Pons1.56 ± 0.52
Cerebellar Cortex1.82 ± 0.98
Cerebellar Nuclei2.16 ± 0.68
Claustrum2.7 ± 0.78
Epithalamus1.68 ± 0.67
Frontal Lobe1.68 ± 0.74
Globus Pallidus2.24 ± 0.34
Hypothalamus1.84 ± 0.81
Insula1.96 ± 0.8
Limbic Lobe1.84 ± 0.68
Mesencephalon2.03 ± 0.81
Myelencephalon1.88 ± 0.74
Occipital Lobe2.09 ± 0.71
Parietal Lobe1.91 ± 0.83
Pontine Tegmentum1.95 ± 0.77
Striatum1.95 ± 0.58
Subthalamus2.05 ± 0.84
Temporal Lobe1.85 ± 0.82
Thalamus1.84 ± 0.69
White Matter2.25 ± 0.21
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Myh4CBCerebellum36.71
55.24
Myh4LSXLateral septal complex61.74
52.75
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
MYH4_HUMAN_1639 10 1639 1648 QAAEALRNLR PRIDE
PAp00001228 9 699 707 CNGVLEGIR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved