AutismKB 2.0

Annotation Detail for MYH6


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Basic Information Top
Gene Symbol:MYH6 ( ASD3,CMD1EE,CMH14,MYHC,MYHCA,alpha-MHC )
Gene Full Name: myosin, heavy chain 6, cardiac muscle, alpha
Band: 14q11.2
Quick LinksEntrez ID:4624; OMIM: 160710; Uniprot ID:MYH6_HUMAN; ENSEMBL ID: ENSG00000197616; HGNC ID: 7576
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body2 / 7076128
blastocyst0 / 623190 
fetus13 / 56401223
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult13 / 19391216
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor3 / 13630222
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal34 / 336030710
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain0 / 11009890 
cervix0 / 481710 
connective tissue0 / 1492550 
ear0 / 162120 
embryonic tissue3 / 21572213
esophagus0 / 202090 
eye0 / 2110540 
heart23 / 89626256
intestine0 / 2344720 
kidney0 / 2117770 
larynx1 / 2414541
liver1 / 2077434
lung2 / 3369745
lymph0 / 442700 
lymph node0 / 916100 
mammary gland1 / 1532716
mouth3 / 6705244
muscle6 / 10771555
nerve0 / 157680 
ovary0 / 1020510 
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 214468_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.75
Adipocyte5.85
AdrenalCortex8.15
Adrenalgland5.3
Amygdala6
Appendix7.25
AtrioventricularNode5.4
BDCA4+_DentriticCells5.95
Bonemarrow6.3
BronchialEpithelialCells5.7
CD105+_Endothelial5.95
CD14+_Monocytes6.5
CD19+_BCells(neg._sel.)6.15
CD33+_Myeloid7.4
CD34+7.1
CD4+_Tcells6.15
CD56+_NKCells6.7
CD71+_EarlyErythroid5.75
CD8+_Tcells5.4
CardiacMyocytes12.45
Caudatenucleus5.35
Cerebellum4.9
CerebellumPeduncles7.15
CiliaryGanglion6.55
CingulateCortex6.5
Colorectaladenocarcinoma6.1
DorsalRootGanglion5.45
FetalThyroid63.6
Fetalbrain5.85
Fetalliver5.3
Fetallung5.25
GlobusPallidus4.7
Heart2706.05
Hypothalamus6.2
Kidney5.15
Leukemia_chronicMyelogenousK-5625.3
Leukemia_promyelocytic-HL-605.25
Leukemialymphoblastic(MOLT-4)4.65
Liver9.3
Lung6.55
Lymphnode4.9
Lymphoma_burkitts(Daudi)7.75
Lymphoma_burkitts(Raji)9
MedullaOblongata5.35
OccipitalLobe5.3
OlfactoryBulb4.65
Ovary4.25
Pancreas4.95
PancreaticIslet6.5
ParietalLobe6.65
Pituitary6.9
Placenta5.95
Pons5.9
PrefrontalCortex7.15
Prostate6.8
Salivarygland5.2
SkeletalMuscle43.55
Skin6.35
SmoothMuscle6.7
Spinalcord6.35
SubthalamicNucleus5.65
SuperiorCervicalGanglion7.95
TemporalLobe5.65
Testis5.1
TestisGermCell4.8
TestisIntersitial5.1
TestisLeydigCell6.45
TestisSeminiferousTubule5.1
Thalamus6.2
Thymus4.55
Thyroid7.3
Tongue11.75
Tonsil5.95
Trachea4.95
TrigeminalGanglion8.25
Uterus4.75
UterusCorpus6.7
WholeBlood6.45
Wholebrain4.8
colon5.95
pineal_day7.32
pineal_night7.22
retina7.2
small_intestine5.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P934145
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.21 ± 1.15
Basal Forebrain1.53 ± 0.29
Basal Part of Pons1.47 ± 0.89
Cerebellar Cortex1.48 ± 0.96
Cerebellar Nuclei1.88 ± 0.82
Claustrum2.66 ± 1.02
Epithalamus1.22 ± 0.84
Frontal Lobe1.49 ± 0.83
Globus Pallidus2.22 ± 0.41
Hypothalamus1.71 ± 0.82
Insula1.36 ± 0.61
Limbic Lobe1.56 ± 0.76
Mesencephalon1.78 ± 0.82
Myelencephalon1.64 ± 0.74
Occipital Lobe1.58 ± 0.64
Parietal Lobe1.68 ± 0.97
Pontine Tegmentum1.66 ± 0.77
Striatum1.77 ± 0.71
Subthalamus1.74 ± 0.68
Temporal Lobe1.49 ± 0.82
Thalamus1.61 ± 0.62
White Matter2.03 ± 0.49
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00001228 9 697 705 CNGVLEGIR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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