AutismKB 2.0

Annotation Detail for MYH10


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Basic Information Top
Gene Symbol:MYH10 ( MGC134913,MGC134914,NMMHCB )
Gene Full Name: myosin, heavy chain 10, non-muscle
Band: 17p13.1
Quick LinksEntrez ID:4628; OMIM: 160776; Uniprot ID:MYH10_HUMAN; ENSEMBL ID: ENSG00000133026; HGNC ID: 7568
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body39 / 70761551
blastocyst35 / 62319561
fetus68 / 564012120
neonate6 / 31097192
infant0 / 236200 
juvenile6 / 55556107
adult122 / 193912162
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor2 / 12794156
bladder carcinoma1 / 1747557
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma7 / 8282384
colorectal tumor6 / 11424652
esophageal tumor1 / 1729057
gastrointestinal tumor2 / 11936916
germ cell tumor26 / 26384598
glioma5 / 10688346
head and neck tumor5 / 13630236
kidney tumor3 / 6895943
leukemia5 / 9584252
liver tumor1 / 9635910
lung tumor7 / 10312767
lymphoma1 / 7175513
non-neoplasia1 / 9725010
normal339 / 3360307100
ovarian tumor7 / 7668291
pancreatic tumor6 / 10461657
primitive neuroectodermal tumor of the CNS8 / 12568063
prostate cancer4 / 10268038
retinoblastoma16 / 46356345
skin tumor19 / 124949152
soft tissue/muscle tissue tumor9 / 12519171
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue6 / 13106457
adrenal gland5 / 33197150
ascites0 / 400150 
bladder1 / 2975733
blood9 / 12347872
bone7 / 7165597
bone marrow0 / 488010 
brain58 / 110098952
cervix0 / 481710 
connective tissue6 / 14925540
ear6 / 16212370
embryonic tissue86 / 215722398
esophagus1 / 2020949
eye33 / 211054156
heart16 / 89626178
intestine6 / 23447225
kidney10 / 21177747
larynx1 / 2414541
liver4 / 20774319
lung27 / 33697480
lymph1 / 4427022
lymph node1 / 9161010
mammary gland8 / 15327152
mouth2 / 6705229
muscle5 / 10771546
nerve3 / 15768190
ovary10 / 10205197
pancreas12 / 21481255
parathyroid4 / 20539194
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta19 / 28082567
prostate7 / 18934536
salivary gland0 / 201550 
skin26 / 210574123
spleen0 / 539520 
stomach2 / 9661920
testis19 / 33044257
thymus1 / 8113112
thyroid6 / 47473126
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord6 / 13680438
uterus19 / 23287881
vascular6 / 51780115
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 213067_at
Cell line Expression level Expression bar
721_B_lymphoblasts5
Adipocyte4.05
AdrenalCortex4.4
Adrenalgland3.5
Amygdala4.35
Appendix4.2
AtrioventricularNode3.25
BDCA4+_DentriticCells4.45
Bonemarrow4.05
BronchialEpithelialCells4.15
CD105+_Endothelial8.65
CD14+_Monocytes4.35
CD19+_BCells(neg._sel.)4.3
CD33+_Myeloid5.2
CD34+7.1
CD4+_Tcells4.4
CD56+_NKCells4.9
CD71+_EarlyErythroid13.4
CD8+_Tcells3.95
CardiacMyocytes6.6
Caudatenucleus3.65
Cerebellum3.35
CerebellumPeduncles4.7
CiliaryGanglion2.9
CingulateCortex4.25
Colorectaladenocarcinoma4.1
DorsalRootGanglion3.2
FetalThyroid4
Fetalbrain4.1
Fetalliver4.05
Fetallung3.5
GlobusPallidus3.2
Heart5.4
Hypothalamus4.45
Kidney3.4
Leukemia_chronicMyelogenousK-5623.7
Leukemia_promyelocytic-HL-603.6
Leukemialymphoblastic(MOLT-4)3.5
Liver5.5
Lung4.5
Lymphnode3.5
Lymphoma_burkitts(Daudi)5.25
Lymphoma_burkitts(Raji)5.8
MedullaOblongata3.7
OccipitalLobe3.7
OlfactoryBulb3.2
Ovary2.75
Pancreas3.3
PancreaticIslet4.4
ParietalLobe4.4
Pituitary4.75
Placenta4.2
Pons3.9
PrefrontalCortex5.1
Prostate4.8
Salivarygland3.3
SkeletalMuscle4.85
Skin3.25
SmoothMuscle68.25
Spinalcord4.4
SubthalamicNucleus3.75
SuperiorCervicalGanglion4.7
TemporalLobe3.75
Testis3.5
TestisGermCell3.4
TestisIntersitial3.45
TestisLeydigCell4.1
TestisSeminiferousTubule3.55
Thalamus4.2
Thymus3.2
Thyroid5.1
Tongue4.1
Tonsil4
Trachea3.4
TrigeminalGanglion4.15
Uterus3.4
UterusCorpus3.7
WholeBlood4.45
Wholebrain3.5
colon4.15
pineal_day7.28
pineal_night9.64
retina4.9
small_intestine3.95
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P34168
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.16 ± 0.28
Basal Forebrain9.62 ± 0.19
Basal Part of Pons10.23 ± 0.31
Cerebellar Cortex9.69 ± 0.23
Cerebellar Nuclei10.15 ± 0.38
Claustrum10.47 ± 0.63
Epithalamus9.32 ± 0.33
Frontal Lobe9.9 ± 0.43
Globus Pallidus9.36 ± 0.19
Hypothalamus9.56 ± 0.48
Insula9.86 ± 0.26
Limbic Lobe10.18 ± 0.35
Mesencephalon9.74 ± 0.49
Myelencephalon9.85 ± 0.36
Occipital Lobe10.07 ± 0.43
Parietal Lobe9.96 ± 0.39
Pontine Tegmentum9.94 ± 0.36
Striatum10.16 ± 0.34
Subthalamus9.71 ± 0.19
Temporal Lobe9.89 ± 0.31
Thalamus9.9 ± 0.36
White Matter8.22 ± 0.37
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Myh10CBCerebellum41.39
100
Myh10CTXCerebral cortex100
100
Myh10HIPHippocampal region44.28
77.21
Myh10HPFHippocampal formation39.68
56.72
Myh10HYHypothalamus45.05
41.34
Myh10LSXLateral septal complex42.19
34.81
Myh10MBMidbrain51.85
55.06
Myh10MYMedulla58.16
79.67
Myh10OLFOlfactory bulb80.98
87.21
Myh10PPons49.94
66.95
Myh10PALPallidum56.61
64.25
Myh10RHPRetrohippocampal region29.81
25.86
Myh10sAMYStriatum-like amygdalar nuclei71.31
62.71
Myh10STRStriatum100
100
Myh10STRdStriatum dorsal region100
100
Myh10STRvStriatum ventral region100
95.73
Myh10THThalamus82.85
88.82
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
MYH10_HUMAN_0 0 0 0 AGVLAHLEEER PRIDE
MYH10_HUMAN_0 0 0 0 AGVLAHLEEERDLK PRIDE
MYH10_HUMAN_0 0 0 0 FDQLLAEEK PRIDE
MYH10_HUMAN_0 0 0 0 KFDQLLAEEK PRIDE
MYH10_HUMAN_0 0 0 0 LDPHLVLDQLR PRIDE
MYH10_HUMAN_1051 8 1051 1058 QELEKAKR PRIDE
MYH10_HUMAN_1161 12 1161 1172 TTAAQQELRTKR PRIDE
MYH10_HUMAN_1340 20 1340 1359 QLEEEKNSLQEQQEEEEEAR PRIDE
MYH10_HUMAN_1441 26 1441 1466 QVASNLEKKQKKFDQLLAEEKSISAR PRIDE
MYH10_HUMAN_1451 10 1451 1460 KFDQLLAEEK PRIDE
MYH10_HUMAN_1452 9 1452 1460 FDQLLAEEK PRIDE
MYH10_HUMAN_1536 10 1536 1545 ALEQQVEEMR PRIDE
MYH10_HUMAN_1545 17 1545 1561 TQLEELEDELQATEDAK PRIDE
MYH10_HUMAN_1599 11 1599 1609 ELEAELEDERK PRIDE
MYH10_HUMAN_1738 21 1738 1758 IAQLEEELEEEQSNMELLNDR PRIDE
MYH10_HUMAN_1885 11 1885 1895 QLEEAEEEATR PRIDE
MYH10_HUMAN_482 19 482 500 LQQLFNHTMFILEQEEYQR PRIDE
MYH10_HUMAN_570 13 570 582 DKADFCIIHYAGK PRIDE
MYH10_HUMAN_570 17 570 586 DKADFCIIHYAGKVDYK PRIDE
MYH10_HUMAN_572 11 572 582 ADFCIIHYAGK PRIDE
MYH10_HUMAN_572 15 572 586 ADFCIIHYAGKVDYK PRIDE
MYH10_HUMAN_583 11 583 593 VDYKADEWLMK PRIDE
MYH10_HUMAN_587 7 587 593 ADEWLMK PRIDE
MYH10_HUMAN_625 20 625 644 IVGLDQVTGMTETAFGSAYK PRIDE
MYH10_HUMAN_669 8 669 676 NTNPNFVR PRIDE
MYH10_HUMAN_686 14 686 699 AGKLDPHLVLDQLR PRIDE
MYH10_HUMAN_689 11 689 699 LDPHLVLDQLR PRIDE
MYH10_HUMAN_700 9 700 708 CNGVLEGIR PRIDE
MYH10_HUMAN_771 11 771 781 AGVLAHLEEER PRIDE
MYH10_HUMAN_771 14 771 784 AGVLAHLEEERDLK PRIDE
MYH10_HUMAN_83 23 83 105 FSKVEDMAELTCLNEASVLHNLK PRIDE
MYH10_HUMAN_86 20 86 105 VEDMAELTCLNEASVLHNLK PRIDE
MYH10_HUMAN_871 10 871 880 VEGELEEMER PRIDE
PAp00000251 11 573 583 ADFCIIHYAGK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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