AutismKB 2.0

Annotation Detail for ZFHX3


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Basic Information Top
Gene Symbol:ZFHX3 ( ATBF1,ATBT,ZNF927 )
Gene Full Name: zinc finger homeobox 3
Band: 16q22.2-q22.3
Quick LinksEntrez ID:463; OMIM: 104155; Uniprot ID:ZFHX3_HUMAN; ENSEMBL ID: ENSG00000140836; HGNC ID: 777
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body4 / 7076156
blastocyst1 / 6231916
fetus20 / 56401235
neonate0 / 310970 
infant0 / 236200 
juvenile2 / 5555635
adult71 / 193912136
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor2 / 9417821
cervical tumor2 / 3436658
chondrosarcoma1 / 8282312
colorectal tumor9 / 11424678
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor12 / 26384545
glioma5 / 10688346
head and neck tumor6 / 13630244
kidney tumor0 / 689590 
leukemia0 / 958420 
liver tumor1 / 9635910
lung tumor6 / 10312758
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal97 / 336030728
ovarian tumor2 / 7668226
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer4 / 10268038
retinoblastoma0 / 463560 
skin tumor3 / 12494924
soft tissue/muscle tissue tumor2 / 12519115
uterine tumor3 / 9025733
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood0 / 1234780 
bone2 / 7165527
bone marrow0 / 488010 
brain22 / 110098919
cervix2 / 4817141
connective tissue1 / 1492556
ear3 / 16212185
embryonic tissue11 / 21572250
esophagus0 / 202090 
eye18 / 21105485
heart1 / 8962611
intestine11 / 23447246
kidney2 / 2117779
larynx1 / 2414541
liver9 / 20774343
lung17 / 33697450
lymph0 / 442700 
lymph node3 / 9161032
mammary gland8 / 15327152
mouth1 / 6705214
muscle3 / 10771527
nerve2 / 15768126
ovary2 / 10205119
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta7 / 28082524
prostate10 / 18934552
salivary gland1 / 2015549
skin8 / 21057437
spleen0 / 539520 
stomach0 / 966190 
testis8 / 33044224
thymus1 / 8113112
thyroid4 / 4747384
tonsil1 / 1699958
trachea0 / 524130 
umbilical cord0 / 136800 
uterus6 / 23287825
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 208033_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.65
Adipocyte6.55
AdrenalCortex6.2
Adrenalgland3.9
Amygdala4.75
Appendix4.55
AtrioventricularNode3.45
BDCA4+_DentriticCells4.9
Bonemarrow4.55
BronchialEpithelialCells4.45
CD105+_Endothelial4.5
CD14+_Monocytes4.85
CD19+_BCells(neg._sel.)4.8
CD33+_Myeloid5.75
CD34+6
CD4+_Tcells4.8
CD56+_NKCells5.2
CD71+_EarlyErythroid4.2
CD8+_Tcells4.4
CardiacMyocytes6.2
Caudatenucleus4.05
Cerebellum3.65
CerebellumPeduncles5.15
CiliaryGanglion3.2
CingulateCortex4.6
Colorectaladenocarcinoma6.75
DorsalRootGanglion3.5
FetalThyroid21.15
Fetalbrain4.45
Fetalliver3.95
Fetallung3.9
GlobusPallidus3.3
Heart5.8
Hypothalamus4.8
Kidney3.65
Leukemia_chronicMyelogenousK-5624.1
Leukemia_promyelocytic-HL-603.95
Leukemialymphoblastic(MOLT-4)3.6
Liver6.15
Lung5.25
Lymphnode3.85
Lymphoma_burkitts(Daudi)5.75
Lymphoma_burkitts(Raji)6.25
MedullaOblongata4.1
OccipitalLobe4.05
OlfactoryBulb3.55
Ovary3
Pancreas3.6
PancreaticIslet4.8
ParietalLobe4.85
Pituitary5.3
Placenta4.95
Pons4.3
PrefrontalCortex5.75
Prostate47.7
Salivarygland3.6
SkeletalMuscle5.25
Skin3.5
SmoothMuscle5.25
Spinalcord4.8
SubthalamicNucleus4.25
SuperiorCervicalGanglion5.3
TemporalLobe4.1
Testis3.85
TestisGermCell3.8
TestisIntersitial3.8
TestisLeydigCell4.5
TestisSeminiferousTubule3.85
Thalamus4.65
Thymus3.55
Thyroid6.15
Tongue4.5
Tonsil4.35
Trachea3.8
TrigeminalGanglion4.45
Uterus9.15
UterusCorpus4.1
WholeBlood4.9
Wholebrain3.75
colon4.55
pineal_day10
pineal_night6.94
retina30.45
small_intestine4.35
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_11194_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.08 ± 0.92
Basal Forebrain2.92 ± 0.57
Basal Part of Pons2.44 ± 0.73
Cerebellar Cortex2.44 ± 0.52
Cerebellar Nuclei2.88 ± 0.71
Claustrum3.46 ± 1.05
Epithalamus2.86 ± 0.47
Frontal Lobe2.8 ± 0.83
Globus Pallidus4.03 ± 0.58
Hypothalamus3.01 ± 0.85
Insula2.89 ± 0.73
Limbic Lobe2.75 ± 0.91
Mesencephalon3.35 ± 0.86
Myelencephalon3.12 ± 0.78
Occipital Lobe2.94 ± 0.79
Parietal Lobe2.92 ± 0.92
Pontine Tegmentum2.94 ± 0.75
Striatum3.94 ± 0.83
Subthalamus3.43 ± 0.76
Temporal Lobe2.91 ± 0.82
Thalamus3.73 ± 0.7
White Matter3.44 ± 0.67
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Atbf1CBCerebellum7.96
9.19
Atbf1CTXCerebral cortex4.38
3.47
Atbf1HIPHippocampal region6.62
7.77
Atbf1HPFHippocampal formation5.67
6.14
Atbf1HYHypothalamus39.48
35.45
Atbf1LSXLateral septal complex24.78
18.63
Atbf1MBMidbrain40.1
40
Atbf1MYMedulla23.8
29.17
Atbf1OLFOlfactory bulb7.92
6.16
Atbf1PPons17.47
17.74
Atbf1PALPallidum9.53
8.52
Atbf1RHPRetrohippocampal region4.47
4.31
Atbf1sAMYStriatum-like amygdalar nuclei36.21
30.41
Atbf1STRStriatum7.47
5.91
Atbf1STRdStriatum dorsal region2.43
1.89
Atbf1STRvStriatum ventral region2.75
2
Atbf1THThalamus83.6
79.84
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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