AutismKB 2.0

Annotation Detail for MYO1C


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Basic Information Top
Gene Symbol:MYO1C ( FLJ23903,MMI-beta,MMIb,NMI,myr2 )
Gene Full Name: myosin IC
Band: 17p13.3
Quick LinksEntrez ID:4641; OMIM: 606538; Uniprot ID:MYO1C_HUMAN; ENSEMBL ID: ENSG00000197879; HGNC ID: 7597
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst3 / 6231948
fetus43 / 56401276
neonate21 / 31097675
infant0 / 236200 
juvenile0 / 555560 
adult264 / 1939121136
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor15 / 94178159
cervical tumor14 / 34366407
chondrosarcoma17 / 82823205
colorectal tumor35 / 114246306
esophageal tumor0 / 172900 
gastrointestinal tumor28 / 119369234
germ cell tumor24 / 26384590
glioma6 / 10688356
head and neck tumor29 / 136302212
kidney tumor20 / 68959290
leukemia0 / 958420 
liver tumor20 / 96359207
lung tumor13 / 103127126
lymphoma10 / 71755139
non-neoplasia15 / 97250154
normal360 / 3360307107
ovarian tumor14 / 76682182
pancreatic tumor39 / 104616372
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer28 / 102680272
retinoblastoma5 / 46356107
skin tumor12 / 12494996
soft tissue/muscle tissue tumor16 / 125191127
uterine tumor10 / 90257110
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue4 / 13106305
adrenal gland0 / 331970 
ascites5 / 40015124
bladder1 / 2975733
blood1 / 1234788
bone8 / 71655111
bone marrow2 / 4880140
brain58 / 110098952
cervix15 / 48171311
connective tissue14 / 14925593
ear0 / 162120 
embryonic tissue13 / 21572260
esophagus0 / 202090 
eye21 / 21105499
heart17 / 89626189
intestine64 / 234472272
kidney42 / 211777198
larynx3 / 24145124
liver30 / 207743144
lung66 / 336974195
lymph3 / 4427067
lymph node23 / 91610251
mammary gland40 / 153271260
mouth9 / 67052134
muscle6 / 10771555
nerve0 / 157680 
ovary29 / 102051284
pancreas51 / 214812237
parathyroid4 / 20539194
pharynx10 / 41328241
pituitary gland1 / 1658560
placenta38 / 280825135
prostate51 / 189345269
salivary gland5 / 20155248
skin30 / 210574142
spleen4 / 5395274
stomach12 / 96619124
testis23 / 33044269
thymus4 / 8113149
thyroid3 / 4747363
tonsil1 / 1699958
trachea16 / 52413305
umbilical cord24 / 136801754
uterus56 / 232878240
vascular9 / 51780173
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 214656_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts224.4
Adipocyte248.95
AdrenalCortex356.6
Adrenalgland163.95
Amygdala189.75
Appendix203.25
AtrioventricularNode228.2
BDCA4+_DentriticCells156.35
Bonemarrow184.35
BronchialEpithelialCells187.45
CD105+_Endothelial185.85
CD14+_Monocytes133.8
CD19+_BCells(neg._sel.)177.8
CD33+_Myeloid181.45
CD34+191.95
CD4+_Tcells197.15
CD56+_NKCells115.4
CD71+_EarlyErythroid71.95
CD8+_Tcells173.4
CardiacMyocytes178.6
Caudatenucleus147.55
Cerebellum140.4
CerebellumPeduncles232.5
CiliaryGanglion165.15
CingulateCortex193
Colorectaladenocarcinoma238.05
DorsalRootGanglion171.2
FetalThyroid184.4
Fetalbrain189.45
Fetalliver152.6
Fetallung167.9
GlobusPallidus160.2
Heart241
Hypothalamus189.15
Kidney175.2
Leukemia_chronicMyelogenousK-562166.05
Leukemia_promyelocytic-HL-60142.45
Leukemialymphoblastic(MOLT-4)111.2
Liver222.65
Lung351.8
Lymphnode183.35
Lymphoma_burkitts(Daudi)207.15
Lymphoma_burkitts(Raji)248.65
MedullaOblongata188.35
OccipitalLobe171.7
OlfactoryBulb270.3
Ovary116.05
Pancreas192.6
PancreaticIslet242.65
ParietalLobe242.8
Pituitary222.35
Placenta309.95
Pons232.35
PrefrontalCortex237.95
Prostate354.7
Salivarygland147.7
SkeletalMuscle189.9
Skin179.15
SmoothMuscle215.95
Spinalcord173.3
SubthalamicNucleus215.65
SuperiorCervicalGanglion358.4
TemporalLobe161.8
Testis162.9
TestisGermCell207.15
TestisIntersitial211.9
TestisLeydigCell179.3
TestisSeminiferousTubule181.2
Thalamus194.8
Thymus187.9
Thyroid242.1
Tongue276.5
Tonsil266.4
Trachea156.05
TrigeminalGanglion270.4
Uterus251.3
UterusCorpus191.85
WholeBlood140.6
Wholebrain100
colon193.6
pineal_day230.06
pineal_night225.76
retina291.9
small_intestine211.15
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P164022
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala14.18 ± 0.41
Basal Forebrain14.07 ± 0.19
Basal Part of Pons13.94 ± 0.14
Cerebellar Cortex14.3 ± 0.33
Cerebellar Nuclei13.95 ± 0.33
Claustrum14.37 ± 0.29
Epithalamus13.87 ± 0.29
Frontal Lobe14.05 ± 0.32
Globus Pallidus14.13 ± 0.31
Hypothalamus13.97 ± 0.22
Insula13.98 ± 0.48
Limbic Lobe14.1 ± 0.37
Mesencephalon14.1 ± 0.42
Myelencephalon14.08 ± 0.35
Occipital Lobe14.15 ± 0.43
Parietal Lobe14.06 ± 0.35
Pontine Tegmentum14.05 ± 0.29
Striatum13.99 ± 0.34
Subthalamus14.02 ± 0.37
Temporal Lobe14.09 ± 0.35
Thalamus13.99 ± 0.32
White Matter14.66 ± 0.08
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Myo1cCBCerebellum6
6.57
Myo1cCTXCerebral cortex9.32
6.46
Myo1cHIPHippocampal region10.58
9.59
Myo1cHPFHippocampal formation16.99
14.23
Myo1cHYHypothalamus12.34
9.1
Myo1cLSXLateral septal complex0.95
0.72
Myo1cMBMidbrain7.07
6.79
Myo1cMYMedulla15.01
18.02
Myo1cOLFOlfactory bulb12.16
8.37
Myo1cPPons22.96
23.57
Myo1cPALPallidum15.4
12.92
Myo1cRHPRetrohippocampal region29.68
21.51
Myo1csAMYStriatum-like amygdalar nuclei17.26
12.19
Myo1cSTRStriatum3.94
3.05
Myo1cSTRdStriatum dorsal region2.02
1.67
Myo1cSTRvStriatum ventral region5.75
4.46
Myo1cTHThalamus12.48
9.13
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
MYO1C_HUMAN_138 15 138 152 LLQSNPVLEAFGNAK PRIDE
MYO1C_HUMAN_166 9 166 174 YMDVQFDFK PRIDE
MYO1C_HUMAN_570 13 570 582 MSLLQLVEILQSK PRIDE
MYO1C_HUMAN_570 19 570 588 MSLLQLVEILQSKEPAYVR PRIDE
MYO1C_HUMAN_612 9 612 620 YLGLLENLR PRIDE
MYO1C_HUMAN_70 20 70 89 GVSFYEVPPHLFAVADTVYR PRIDE
MYO1C_HUMAN_778 8 778 785 TSFLLNLR PRIDE
MYO1C_HUMAN_996 16 996 1011 DGTIDFTPGSELLITK PRIDE
PAp00009606 12 802 813 CPENAFFLDHVR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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