AutismKB 2.0

Annotation Detail for MYO1E


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Basic Information Top
Gene Symbol:MYO1E ( HuncM-IC,MGC104638,MYO1C )
Gene Full Name: myosin IE
Band: 15q22.2
Quick LinksEntrez ID:4643; OMIM: 601479; Uniprot ID:MYO1E_HUMAN; ENSEMBL ID: ENSG00000157483; HGNC ID: 7599
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst5 / 6231980
fetus8 / 56401214
neonate0 / 310970 
infant0 / 236200 
juvenile8 / 55556143
adult127 / 193912165
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor4 / 9417842
cervical tumor14 / 34366407
chondrosarcoma9 / 82823108
colorectal tumor11 / 11424696
esophageal tumor1 / 1729057
gastrointestinal tumor20 / 119369167
germ cell tumor21 / 26384579
glioma2 / 10688318
head and neck tumor13 / 13630295
kidney tumor5 / 6895972
leukemia1 / 9584210
liver tumor15 / 96359155
lung tumor6 / 10312758
lymphoma35 / 71755487
non-neoplasia1 / 9725010
normal162 / 336030748
ovarian tumor2 / 7668226
pancreatic tumor14 / 104616133
primitive neuroectodermal tumor of the CNS1 / 1256807
prostate cancer2 / 10268019
retinoblastoma2 / 4635643
skin tumor8 / 12494964
soft tissue/muscle tissue tumor8 / 12519163
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites15 / 40015374
bladder1 / 2975733
blood1 / 1234788
bone5 / 7165569
bone marrow0 / 488010 
brain32 / 110098929
cervix14 / 48171290
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue11 / 21572250
esophagus1 / 2020949
eye6 / 21105428
heart1 / 8962611
intestine20 / 23447285
kidney13 / 21177761
larynx4 / 24145165
liver21 / 207743101
lung19 / 33697456
lymph35 / 44270790
lymph node31 / 91610338
mammary gland13 / 15327184
mouth5 / 6705274
muscle13 / 107715120
nerve1 / 1576863
ovary3 / 10205129
pancreas14 / 21481265
parathyroid0 / 205390 
pharynx2 / 4132848
pituitary gland0 / 165850 
placenta17 / 28082560
prostate7 / 18934536
salivary gland0 / 201550 
skin12 / 21057456
spleen4 / 5395274
stomach3 / 9661931
testis12 / 33044236
thymus0 / 811310 
thyroid4 / 4747384
tonsil2 / 16999117
trachea11 / 52413209
umbilical cord0 / 136800 
uterus25 / 232878107
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203072_at
Cell line Expression level Expression bar
721_B_lymphoblasts71.75
Adipocyte8.95
AdrenalCortex7.95
Adrenalgland6.6
Amygdala7.5
Appendix7.8
AtrioventricularNode5.85
BDCA4+_DentriticCells62.55
Bonemarrow7.4
BronchialEpithelialCells10.75
CD105+_Endothelial6.75
CD14+_Monocytes8.45
CD19+_BCells(neg._sel.)8.55
CD33+_Myeloid9.75
CD34+10.1
CD4+_Tcells8
CD56+_NKCells8.9
CD71+_EarlyErythroid7.6
CD8+_Tcells6.45
CardiacMyocytes8.5
Caudatenucleus7.1
Cerebellum6.45
CerebellumPeduncles9.1
CiliaryGanglion5.4
CingulateCortex8
Colorectaladenocarcinoma8.35
DorsalRootGanglion5.95
FetalThyroid8.25
Fetalbrain7.45
Fetalliver6.75
Fetallung6.7
GlobusPallidus5.65
Heart9.75
Hypothalamus8.9
Kidney6.45
Leukemia_chronicMyelogenousK-5626.75
Leukemia_promyelocytic-HL-607.05
Leukemialymphoblastic(MOLT-4)6.35
Liver11.6
Lung8.85
Lymphnode6.7
Lymphoma_burkitts(Daudi)15.95
Lymphoma_burkitts(Raji)10.65
MedullaOblongata7.3
OccipitalLobe7.15
OlfactoryBulb7.7
Ovary5.2
Pancreas9.5
PancreaticIslet8.4
ParietalLobe8.5
Pituitary8.8
Placenta8.35
Pons7.55
PrefrontalCortex9.3
Prostate14.25
Salivarygland6.3
SkeletalMuscle11.3
Skin5.75
SmoothMuscle9.05
Spinalcord8.5
SubthalamicNucleus7.1
SuperiorCervicalGanglion9.1
TemporalLobe7.15
Testis6.4
TestisGermCell6.65
TestisIntersitial6.6
TestisLeydigCell7.85
TestisSeminiferousTubule6.8
Thalamus8.2
Thymus6.4
Thyroid10
Tongue7.95
Tonsil7.75
Trachea6.6
TrigeminalGanglion7.7
Uterus7.4
UterusCorpus13.3
WholeBlood8.65
Wholebrain6.6
colon14
pineal_day9.7
pineal_night9.58
retina10.35
small_intestine7.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_1908_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.92 ± 0.89
Basal Forebrain2.79 ± 0.73
Basal Part of Pons2.77 ± 0.77
Cerebellar Cortex2.43 ± 0.69
Cerebellar Nuclei3.66 ± 0.83
Claustrum3.29 ± 1
Epithalamus3.9 ± 0.55
Frontal Lobe2.72 ± 0.88
Globus Pallidus4.59 ± 0.45
Hypothalamus2.88 ± 1.18
Insula2.19 ± 0.44
Limbic Lobe2.73 ± 0.9
Mesencephalon3.1 ± 0.95
Myelencephalon2.81 ± 0.83
Occipital Lobe3.19 ± 0.81
Parietal Lobe2.8 ± 0.96
Pontine Tegmentum3.03 ± 0.89
Striatum3.44 ± 0.95
Subthalamus2.79 ± 0.46
Temporal Lobe2.56 ± 0.76
Thalamus2.93 ± 0.64
White Matter5.69 ± 0.43
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Myo1eCBCerebellum0.96
1.55
Myo1eCTXCerebral cortex1.23
1.1
Myo1eHIPHippocampal region0.16
0.15
Myo1eHPFHippocampal formation0.48
0.43
Myo1eHYHypothalamus0.15
0.13
Myo1eLSXLateral septal complex0.36
0.77
Myo1eMBMidbrain0.37
0.51
Myo1eMYMedulla0.45
0.45
Myo1eOLFOlfactory bulb1.7
1.31
Myo1ePPons0.45
0.53
Myo1ePALPallidum0.03
0.02
Myo1eRHPRetrohippocampal region1.06
0.82
Myo1esAMYStriatum-like amygdalar nuclei0.25
0.23
Myo1eSTRStriatum0.33
0.32
Myo1eSTRdStriatum dorsal region0.38
0.36
Myo1eSTRvStriatum ventral region0.17
0.16
Myo1eTHThalamus0.41
0.47
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
MYO1E_HUMAN_453 31 453 483 VNPPGIMSILDDVCATMHAVGEGADQTLLQK PRIDE
PAp00004093 9 445 453 IVCDLIENK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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