AutismKB 2.0

Annotation Detail for MYO5B


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Basic Information Top
Gene Symbol:MYO5B ( KIAA1119 )
Gene Full Name: myosin VB
Band: 18q
Quick LinksEntrez ID:4645; OMIM: 606540; Uniprot ID:MYO5B_HUMAN; ENSEMBL ID: ENSG00000167306; HGNC ID: 7603
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst0 / 623190 
fetus14 / 56401224
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult79 / 193912140
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor7 / 9417874
cervical tumor1 / 3436629
chondrosarcoma2 / 8282324
colorectal tumor11 / 11424696
esophageal tumor0 / 172900 
gastrointestinal tumor8 / 11936967
germ cell tumor4 / 26384515
glioma0 / 1068830 
head and neck tumor4 / 13630229
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor2 / 9635920
lung tumor6 / 10312758
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal96 / 336030728
ovarian tumor4 / 7668252
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer2 / 10268019
retinoblastoma2 / 4635643
skin tumor2 / 12494916
soft tissue/muscle tissue tumor5 / 12519139
uterine tumor6 / 9025766
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites6 / 40015149
bladder1 / 2975733
blood0 / 1234780 
bone0 / 716550 
bone marrow0 / 488010 
brain9 / 11009898
cervix5 / 48171103
connective tissue7 / 14925546
ear0 / 162120 
embryonic tissue6 / 21572227
esophagus0 / 202090 
eye11 / 21105452
heart1 / 8962611
intestine19 / 23447281
kidney6 / 21177728
larynx0 / 241450 
liver4 / 20774319
lung10 / 33697429
lymph0 / 442700 
lymph node1 / 9161010
mammary gland20 / 153271130
mouth0 / 670520 
muscle1 / 1077159
nerve0 / 157680 
ovary4 / 10205139
pancreas5 / 21481223
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta10 / 28082535
prostate5 / 18934526
salivary gland0 / 201550 
skin2 / 2105749
spleen0 / 539520 
stomach3 / 9661931
testis9 / 33044227
thymus0 / 811310 
thyroid5 / 47473105
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus6 / 23287825
vascular0 / 517800 
Microarray in BioGPS Top
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P101193
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.71 ± 0.6
Basal Forebrain6.37 ± 0.5
Basal Part of Pons5.27 ± 0.45
Cerebellar Cortex3.83 ± 0.65
Cerebellar Nuclei4.17 ± 0.64
Claustrum4.6 ± 0.85
Epithalamus5.67 ± 1.85
Frontal Lobe5.33 ± 0.66
Globus Pallidus3.36 ± 1.84
Hypothalamus3.95 ± 0.45
Insula5.25 ± 0.43
Limbic Lobe4.91 ± 1.09
Mesencephalon4.62 ± 1.31
Myelencephalon4.68 ± 0.95
Occipital Lobe3.6 ± 1.13
Parietal Lobe5.23 ± 0.72
Pontine Tegmentum4.41 ± 0.88
Striatum3.63 ± 1.59
Subthalamus5.68 ± 0.87
Temporal Lobe5.09 ± 0.51
Thalamus4.84 ± 1.05
White Matter3.62 ± 0.6
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Myo5bCBCerebellum27.64
49.1
Myo5bCTXCerebral cortex29.59
24.17
Myo5bHIPHippocampal region67.38
81.99
Myo5bHPFHippocampal formation54.3
70.95
Myo5bHYHypothalamus26.85
24.54
Myo5bLSXLateral septal complex88.1
90.12
Myo5bMBMidbrain14.14
13.87
Myo5bMYMedulla27.15
34.22
Myo5bOLFOlfactory bulb52.26
53.08
Myo5bPPons17.02
18.43
Myo5bPALPallidum18.17
17.53
Myo5bRHPRetrohippocampal region37.6
38.19
Myo5bsAMYStriatum-like amygdalar nuclei49.24
44.3
Myo5bSTRStriatum36.76
30.85
Myo5bSTRdStriatum dorsal region24.01
18.42
Myo5bSTRvStriatum ventral region36.38
26.84
Myo5bTHThalamus14.86
14.65
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
MYO5B_HUMAN_1476 8 1476 1483 EDEALLIR PRIDE
PAp00848296 15 504 518 LGILDLLDEECKVPK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018