AutismKB 2.0

Annotation Detail for MYO7A


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Basic Information Top
Gene Symbol:MYO7A ( DFNA11,DFNB2,MYOVIIA,MYU7A,NSRD2,USH1B )
Gene Full Name: myosin VIIA
Band: 11q13.5
Quick LinksEntrez ID:4647; OMIM: 276903; Uniprot ID:MYO7A_HUMAN; ENSEMBL ID: ENSG00000137474; HGNC ID: 7606
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus5 / 5640128
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult48 / 193912124
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma1 / 8282312
colorectal tumor4 / 11424635
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor2 / 2638457
glioma1 / 1068839
head and neck tumor1 / 1363027
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor1 / 1031279
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal60 / 336030717
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma3 / 4635664
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor2 / 9025722
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites0 / 400150 
bladder0 / 297570 
blood0 / 1234780 
bone1 / 7165513
bone marrow0 / 488010 
brain5 / 11009894
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye12 / 21105456
heart0 / 896260 
intestine4 / 23447217
kidney2 / 2117779
larynx1 / 2414541
liver3 / 20774314
lung1 / 3369742
lymph0 / 442700 
lymph node2 / 9161021
mammary gland2 / 15327113
mouth0 / 670520 
muscle0 / 1077150 
nerve1 / 1576863
ovary1 / 1020519
pancreas0 / 2148120 
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta17 / 28082560
prostate4 / 18934521
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis9 / 33044227
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus2 / 2328788
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 33197_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.2
Adipocyte3.6
AdrenalCortex13.85
Adrenalgland8.85
Amygdala3.85
Appendix3.8
AtrioventricularNode2.65
BDCA4+_DentriticCells3.9
Bonemarrow3.65
BronchialEpithelialCells3.5
CD105+_Endothelial3.6
CD14+_Monocytes3.9
CD19+_BCells(neg._sel.)3.55
CD33+_Myeloid4.75
CD34+4.6
CD4+_Tcells3.95
CD56+_NKCells4.2
CD71+_EarlyErythroid3.4
CD8+_Tcells3.55
CardiacMyocytes4.55
Caudatenucleus3.25
Cerebellum2.95
CerebellumPeduncles4.15
CiliaryGanglion2.9
CingulateCortex3.75
Colorectaladenocarcinoma3.65
DorsalRootGanglion3.35
FetalThyroid3.55
Fetalbrain3.65
Fetalliver3.15
Fetallung3.15
GlobusPallidus2.6
Heart4.55
Hypothalamus4
Kidney3.2
Leukemia_chronicMyelogenousK-5623.3
Leukemia_promyelocytic-HL-603.2
Leukemialymphoblastic(MOLT-4)2.9
Liver5.5
Lung4.05
Lymphnode3.15
Lymphoma_burkitts(Daudi)4.7
Lymphoma_burkitts(Raji)5.1
MedullaOblongata3.4
OccipitalLobe3.3
OlfactoryBulb2.9
Ovary2.4
Pancreas2.95
PancreaticIslet4.45
ParietalLobe3.85
Pituitary4.5
Placenta5.4
Pons3.45
PrefrontalCortex4.65
Prostate4.3
Salivarygland2.8
SkeletalMuscle3.95
Skin2.8
SmoothMuscle4.15
Spinalcord3.9
SubthalamicNucleus3.3
SuperiorCervicalGanglion4
TemporalLobe3.3
Testis3.3
TestisGermCell6.95
TestisIntersitial3.6
TestisLeydigCell3.6
TestisSeminiferousTubule4.05
Thalamus3.7
Thymus2.95
Thyroid4.65
Tongue3.5
Tonsil3.55
Trachea3
TrigeminalGanglion3.45
Uterus3.05
UterusCorpus3.15
WholeBlood4.1
Wholebrain3.1
colon3.7
pineal_day45.12
pineal_night46.84
retina9.375
small_intestine3.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P422350
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.07 ± 1.12
Basal Forebrain2.51 ± 0.58
Basal Part of Pons2.58 ± 0.56
Cerebellar Cortex2.32 ± 0.52
Cerebellar Nuclei3.01 ± 0.69
Claustrum3.17 ± 0.76
Epithalamus3.45 ± 0.68
Frontal Lobe2.38 ± 0.76
Globus Pallidus3.66 ± 0.46
Hypothalamus3.23 ± 0.53
Insula2.82 ± 0.54
Limbic Lobe2.67 ± 0.9
Mesencephalon2.74 ± 0.85
Myelencephalon2.76 ± 0.82
Occipital Lobe3.06 ± 0.76
Parietal Lobe2.8 ± 0.87
Pontine Tegmentum2.75 ± 0.79
Striatum2.68 ± 0.86
Subthalamus2.74 ± 0.76
Temporal Lobe2.65 ± 0.79
Thalamus2.43 ± 0.71
White Matter3.96 ± 1.1
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Myo7aCBCerebellum12.86
17.66
Myo7aCTXCerebral cortex13
10.03
Myo7aHIPHippocampal region12.19
16.17
Myo7aHPFHippocampal formation14.53
15.47
Myo7aHYHypothalamus1.52
1.36
Myo7aLSXLateral septal complex4.26
10.45
Myo7aMBMidbrain4.08
5.49
Myo7aMYMedulla12.31
15.82
Myo7aOLFOlfactory bulb12.59
10.67
Myo7aPPons6.06
7.11
Myo7aPALPallidum3.8
3.6
Myo7aRHPRetrohippocampal region17.66
14.35
Myo7asAMYStriatum-like amygdalar nuclei3.55
3.8
Myo7aSTRStriatum5.03
6.01
Myo7aSTRdStriatum dorsal region5.4
6.72
Myo7aSTRvStriatum ventral region3.24
2.33
Myo7aTHThalamus4.56
6.01
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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