AutismKB 2.0

Annotation Detail for NACA


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Basic Information Top
Gene Symbol:NACA ( MGC117224,NACA1 )
Gene Full Name: nascent polypeptide-associated complex alpha subunit
Band: 12q23-q24.1
Quick LinksEntrez ID:4666; OMIM: 601234; Uniprot ID:NACA_HUMAN; ENSEMBL ID: ENSG00000196531; HGNC ID: 7629
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body44 / 70761621
blastocyst13 / 62319208
fetus172 / 564012304
neonate18 / 31097578
infant4 / 23620169
juvenile16 / 55556287
adult863 / 1939121445
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor4 / 12794312
bladder carcinoma8 / 17475457
breast (mammary gland) tumor59 / 94178626
cervical tumor15 / 34366436
chondrosarcoma19 / 82823229
colorectal tumor124 / 1142461085
esophageal tumor4 / 17290231
gastrointestinal tumor47 / 119369393
germ cell tumor74 / 263845280
glioma19 / 106883177
head and neck tumor140 / 1363021027
kidney tumor29 / 68959420
leukemia45 / 95842469
liver tumor60 / 96359622
lung tumor37 / 103127358
lymphoma52 / 71755724
non-neoplasia10 / 97250102
normal1033 / 3360307307
ovarian tumor41 / 76682534
pancreatic tumor71 / 104616678
primitive neuroectodermal tumor of the CNS27 / 125680214
prostate cancer74 / 102680720
retinoblastoma17 / 46356366
skin tumor62 / 124949496
soft tissue/muscle tissue tumor68 / 125191543
uterine tumor35 / 90257387
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue11 / 13106839
adrenal gland11 / 33197331
ascites17 / 40015424
bladder8 / 29757268
blood72 / 123478583
bone44 / 71655614
bone marrow36 / 48801737
brain172 / 1100989156
cervix17 / 48171352
connective tissue17 / 149255113
ear30 / 162121850
embryonic tissue104 / 215722482
esophagus4 / 20209197
eye78 / 211054369
heart39 / 89626435
intestine161 / 234472686
kidney66 / 211777311
larynx84 / 241453478
liver91 / 207743438
lung95 / 336974281
lymph45 / 442701016
lymph node25 / 91610272
mammary gland90 / 153271587
mouth21 / 67052313
muscle59 / 107715547
nerve3 / 15768190
ovary53 / 102051519
pancreas123 / 214812572
parathyroid8 / 20539389
pharynx37 / 41328895
pituitary gland3 / 16585180
placenta61 / 280825217
prostate102 / 189345538
salivary gland10 / 20155496
skin95 / 210574451
spleen13 / 53952240
stomach61 / 96619631
testis64 / 330442193
thymus19 / 81131234
thyroid32 / 47473674
tonsil15 / 16999882
trachea2 / 5241338
umbilical cord17 / 136801242
uterus78 / 232878334
vascular18 / 51780347
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 208635_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts7503.65
Adipocyte2536
AdrenalCortex2151.85
Adrenalgland907.65
Amygdala1780.4
Appendix2012.45
AtrioventricularNode811.85
BDCA4+_DentriticCells7270.3
Bonemarrow963.6
BronchialEpithelialCells3213.1
CD105+_Endothelial4911.4
CD14+_Monocytes5280.35
CD19+_BCells(neg._sel.)6550.85
CD33+_Myeloid6383.2
CD34+8220.65
CD4+_Tcells6709.45
CD56+_NKCells5512.8
CD71+_EarlyErythroid2041.15
CD8+_Tcells5502.15
CardiacMyocytes2452
Caudatenucleus1256.15
Cerebellum1161.75
CerebellumPeduncles1368.25
CiliaryGanglion853.75
CingulateCortex1544
Colorectaladenocarcinoma2170.9
DorsalRootGanglion949.5
FetalThyroid2711.2
Fetalbrain3735.1
Fetalliver1939.7
Fetallung2739.7
GlobusPallidus837.7
Heart960.35
Hypothalamus2521.1
Kidney673.85
Leukemia_chronicMyelogenousK-5624410.05
Leukemia_promyelocytic-HL-603754.7
Leukemialymphoblastic(MOLT-4)3753.45
Liver1037.3
Lung1000.15
Lymphnode3334.45
Lymphoma_burkitts(Daudi)6459.45
Lymphoma_burkitts(Raji)4394.9
MedullaOblongata1307.55
OccipitalLobe1355.3
OlfactoryBulb2220.65
Ovary3173.6
Pancreas2199.1
PancreaticIslet3504.2
ParietalLobe1175.9
Pituitary2975.6
Placenta1257.3
Pons1027.15
PrefrontalCortex2356.8
Prostate1750
Salivarygland2999.4
SkeletalMuscle485.1
Skin1816.6
SmoothMuscle3827.3
Spinalcord2160.8
SubthalamicNucleus1080.75
SuperiorCervicalGanglion710.35
TemporalLobe1307.2
Testis1773.55
TestisGermCell2841.9
TestisIntersitial2577.85
TestisLeydigCell1846.45
TestisSeminiferousTubule1610.8
Thalamus1702.6
Thymus1541.4
Thyroid2941.05
Tongue1831.55
Tonsil3453.45
Trachea1704.5
TrigeminalGanglion789.25
Uterus2941.95
UterusCorpus2749.75
WholeBlood4029.2
Wholebrain1088.95
colon2385
pineal_day3414.14
pineal_night3116.4
retina2235.775
small_intestine1912
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_24_P102043
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala6.15 ± 0.73
Basal Forebrain5.99 ± 0.32
Basal Part of Pons5.92 ± 0.38
Cerebellar Cortex5.93 ± 0.38
Cerebellar Nuclei6.06 ± 0.36
Claustrum6.44 ± 0.53
Epithalamus5.27 ± 0.53
Frontal Lobe5.95 ± 0.47
Globus Pallidus6.09 ± 0.67
Hypothalamus5.88 ± 0.47
Insula5.78 ± 0.4
Limbic Lobe6.03 ± 0.47
Mesencephalon5.97 ± 0.36
Myelencephalon5.96 ± 0.5
Occipital Lobe5.96 ± 0.51
Parietal Lobe5.89 ± 0.48
Pontine Tegmentum5.86 ± 0.39
Striatum6.05 ± 0.44
Subthalamus6.06 ± 0.54
Temporal Lobe5.87 ± 0.5
Thalamus5.94 ± 0.41
White Matter6.07 ± 0.46
Mouse Brain ISH
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
NACA_HUMAN_0 0 0 0 DIELVMSQANVSR PRIDE
NACA_HUMAN_0 0 0 0 IEDLSQQAQLAAAEK PRIDE
NACA_HUMAN_0 0 0 0 IEDLSQQAQLAAAEKFK PRIDE
NACA_HUMAN_0 0 0 0 NILFVITKPDVYK PRIDE
NACA_HUMAN_100 13 100 112 NILFVITKPDVYK PRIDE
NACA_HUMAN_100 27 100 126 NILFVITKPDVYKSPASDTYIVFGEAK PRIDE
NACA_HUMAN_113 14 113 126 SPASDTYIVFGEAK PRIDE
NACA_HUMAN_114 14 114 127 SPASDTYIVFGEAK PRIDE
NACA_HUMAN_127 15 127 141 IEDLSQQAQLAAAEK PRIDE
NACA_HUMAN_127 17 127 143 IEDLSQQAQLAAAEKFK PRIDE
NACA_HUMAN_128 17 128 144 IEDLSQQAQLAAAEKFK PRIDE
NACA_HUMAN_179 13 179 191 DIELVMSQANVSR PRIDE
NACA_HUMAN_197 18 197 214 ALKNNSNDIVNAIMELTM PRIDE
NACA_HUMAN_200 15 200 214 NNSNDIVNAIMELTM PRIDE
PAp00032998 13 180 192 DIELVMSQANVSR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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