AutismKB 2.0

Annotation Detail for NAGA


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Basic Information Top
Gene Symbol:NAGA ( D22S674,GALB )
Gene Full Name: N-acetylgalactosaminidase, alpha-
Band: 22q13.2
Quick LinksEntrez ID:4668; OMIM: 104170; Uniprot ID:NAGAB_HUMAN; ENSEMBL ID: ENSG00000198951; HGNC ID: 7631
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst5 / 6231980
fetus27 / 56401247
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult128 / 193912166
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor3 / 12794234
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor0 / 343660 
chondrosarcoma9 / 82823108
colorectal tumor4 / 11424635
esophageal tumor2 / 17290115
gastrointestinal tumor7 / 11936958
germ cell tumor18 / 26384568
glioma7 / 10688365
head and neck tumor6 / 13630244
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor2 / 9635920
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia8 / 9725082
normal150 / 336030744
ovarian tumor2 / 7668226
pancreatic tumor7 / 10461666
primitive neuroectodermal tumor of the CNS33 / 125680262
prostate cancer5 / 10268048
retinoblastoma1 / 4635621
skin tumor19 / 124949152
soft tissue/muscle tissue tumor4 / 12519131
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland3 / 3319790
ascites1 / 4001524
bladder1 / 2975733
blood3 / 12347824
bone9 / 71655125
bone marrow2 / 4880140
brain23 / 110098920
cervix0 / 481710 
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue8 / 21572237
esophagus2 / 2020998
eye10 / 21105447
heart4 / 8962644
intestine14 / 23447259
kidney8 / 21177737
larynx2 / 2414582
liver5 / 20774324
lung17 / 33697450
lymph0 / 442700 
lymph node2 / 9161021
mammary gland8 / 15327152
mouth2 / 6705229
muscle1 / 1077159
nerve0 / 157680 
ovary4 / 10205139
pancreas14 / 21481265
parathyroid4 / 20539194
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta49 / 280825174
prostate9 / 18934547
salivary gland0 / 201550 
skin22 / 210574104
spleen0 / 539520 
stomach2 / 9661920
testis5 / 33044215
thymus0 / 811310 
thyroid2 / 4747342
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus8 / 23287834
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202944_at
Cell line Expression level Expression bar
721_B_lymphoblasts50.5
Adipocyte4.85
AdrenalCortex5
Adrenalgland4.1
Amygdala5.2
Appendix4.8
AtrioventricularNode3.65
BDCA4+_DentriticCells281.1
Bonemarrow9.8
BronchialEpithelialCells4.8
CD105+_Endothelial5.7
CD14+_Monocytes469.7
CD19+_BCells(neg._sel.)5.3
CD33+_Myeloid353
CD34+14.3
CD4+_Tcells6.5
CD56+_NKCells42.05
CD71+_EarlyErythroid8.7
CD8+_Tcells4.85
CardiacMyocytes6.1
Caudatenucleus4.35
Cerebellum3.9
CerebellumPeduncles5.45
CiliaryGanglion3.35
CingulateCortex5
Colorectaladenocarcinoma4.9
DorsalRootGanglion3.65
FetalThyroid4.6
Fetalbrain4.9
Fetalliver4.2
Fetallung4.6
GlobusPallidus3.5
Heart6.1
Hypothalamus5.35
Kidney6.05
Leukemia_chronicMyelogenousK-5624.6
Leukemia_promyelocytic-HL-604.3
Leukemialymphoblastic(MOLT-4)3.95
Liver6.35
Lung6.95
Lymphnode5.8
Lymphoma_burkitts(Daudi)6.25
Lymphoma_burkitts(Raji)6.8
MedullaOblongata4.45
OccipitalLobe4.35
OlfactoryBulb3.9
Ovary3.5
Pancreas3.9
PancreaticIslet5.2
ParietalLobe5.1
Pituitary5.75
Placenta15.3
Pons4.6
PrefrontalCortex6.15
Prostate5.8
Salivarygland3.9
SkeletalMuscle5.55
Skin3.65
SmoothMuscle5.5
Spinalcord6.45
SubthalamicNucleus4.4
SuperiorCervicalGanglion5.45
TemporalLobe4.3
Testis4.2
TestisGermCell4.2
TestisIntersitial4.1
TestisLeydigCell4.75
TestisSeminiferousTubule4.1
Thalamus4.9
Thymus3.8
Thyroid6.25
Tongue4.7
Tonsil4.7
Trachea8.1
TrigeminalGanglion4.75
Uterus4.1
UterusCorpus4.35
WholeBlood118.5
Wholebrain4.2
colon5.35
pineal_day6.16
pineal_night6.02
retina6.575
small_intestine7.1
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_9444_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.39 ± 0.48
Basal Forebrain5.29 ± 0.3
Basal Part of Pons4.96 ± 0.43
Cerebellar Cortex5.13 ± 0.33
Cerebellar Nuclei5.59 ± 0.44
Claustrum5.53 ± 0.58
Epithalamus5.93 ± 0.35
Frontal Lobe5.09 ± 0.52
Globus Pallidus6.37 ± 0.38
Hypothalamus5.34 ± 0.57
Insula5.19 ± 0.46
Limbic Lobe5.17 ± 0.49
Mesencephalon5.25 ± 0.57
Myelencephalon5.28 ± 0.51
Occipital Lobe5.38 ± 0.49
Parietal Lobe5.16 ± 0.42
Pontine Tegmentum5.32 ± 0.42
Striatum5.31 ± 0.46
Subthalamus5.09 ± 0.11
Temporal Lobe5.11 ± 0.45
Thalamus5.3 ± 0.35
White Matter6.2 ± 0.49
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
NagaCBCerebellum8.48
11.85
NagaCTXCerebral cortex0.68
0.83
NagaHIPHippocampal region5.34
5.49
NagaHPFHippocampal formation6.77
6.36
NagaHYHypothalamus3.12
4.41
NagaLSXLateral septal complex0.5
0.72
NagaMBMidbrain1.14
2.25
NagaMYMedulla1.6
3.16
NagaOLFOlfactory bulb4.02
3.61
NagaPPons1.88
2.79
NagaPALPallidum0.55
0.63
NagaRHPRetrohippocampal region10.1
8.15
NagasAMYStriatum-like amygdalar nuclei1.62
1.63
NagaSTRStriatum1.1
1.35
NagaSTRdStriatum dorsal region1.13
1.31
NagaSTRvStriatum ventral region0.9
1.55
NagaTHThalamus1.4
1.54
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
NAGAB_HUMAN_0 0 0 0 RFPHGIPFLADYVHSLGLK PRIDE
NAGAB_HUMAN_267 20 267 286 AQMALWTVLAAPLLMSTDLR PRIDE
NAGAB_HUMAN_287 17 287 303 TISAQNMDILQNPLMIK PRIDE
NAGAB_HUMAN_304 11 304 314 INQDPLGIQGR PRIDE
NAGAB_HUMAN_334 10 334 343 ASALVFFSCR PRIDE
NAGAB_HUMAN_96 19 96 114 RFPHGIPFLADYVHSLGLK PRIDE
PAp00024713 17 69 85 DMGYTYLNIDDCWIGGR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018