AutismKB 2.0

Annotation Detail for ATF3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ATF3 ( - )
Gene Full Name: activating transcription factor 3
Band: 1q32.3
Quick LinksEntrez ID:467; OMIM: 603148; Uniprot ID:ATF3_HUMAN; ENSEMBL ID: ENSG00000162772; HGNC ID: 785
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst2 / 6231932
fetus20 / 56401235
neonate1 / 3109732
infant0 / 236200 
juvenile6 / 55556107
adult195 / 1939121100
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor4 / 9417842
cervical tumor3 / 3436687
chondrosarcoma7 / 8282384
colorectal tumor4 / 11424635
esophageal tumor2 / 17290115
gastrointestinal tumor10 / 11936983
germ cell tumor26 / 26384598
glioma3 / 10688328
head and neck tumor4 / 13630229
kidney tumor2 / 6895929
leukemia4 / 9584241
liver tumor5 / 9635951
lung tumor2 / 10312719
lymphoma4 / 7175555
non-neoplasia5 / 9725051
normal373 / 3360307111
ovarian tumor5 / 7668265
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS4 / 12568031
prostate cancer0 / 1026800 
retinoblastoma1 / 4635621
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor9 / 12519171
uterine tumor7 / 9025777
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue2 / 13106152
adrenal gland1 / 3319730
ascites5 / 40015124
bladder5 / 29757168
blood19 / 123478153
bone2 / 7165527
bone marrow1 / 4880120
brain53 / 110098948
cervix3 / 4817162
connective tissue6 / 14925540
ear0 / 162120 
embryonic tissue11 / 21572250
esophagus3 / 20209148
eye3 / 21105414
heart13 / 89626145
intestine32 / 234472136
kidney27 / 211777127
larynx0 / 241450 
liver19 / 20774391
lung69 / 336974204
lymph0 / 442700 
lymph node2 / 9161021
mammary gland11 / 15327171
mouth3 / 6705244
muscle4 / 10771537
nerve4 / 15768253
ovary5 / 10205148
pancreas13 / 21481260
parathyroid3 / 20539146
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta58 / 280825206
prostate27 / 189345142
salivary gland0 / 201550 
skin5 / 21057423
spleen5 / 5395292
stomach3 / 9661931
testis8 / 33044224
thymus7 / 8113186
thyroid14 / 47473294
tonsil0 / 169990 
trachea13 / 52413248
umbilical cord0 / 136800 
uterus28 / 232878120
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 202672_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts62.6
Adipocyte7.1
AdrenalCortex116.1
Adrenalgland11.35
Amygdala7.35
Appendix177.3
AtrioventricularNode7.45
BDCA4+_DentriticCells106.1
Bonemarrow7.25
BronchialEpithelialCells7.35
CD105+_Endothelial7.9
CD14+_Monocytes29.4
CD19+_BCells(neg._sel.)7.7
CD33+_Myeloid277.45
CD34+14.3
CD4+_Tcells8.15
CD56+_NKCells10.5
CD71+_EarlyErythroid7.1
CD8+_Tcells6.75
CardiacMyocytes10.15
Caudatenucleus6.85
Cerebellum6.05
CerebellumPeduncles8.55
CiliaryGanglion49.05
CingulateCortex7.65
Colorectaladenocarcinoma19.9
DorsalRootGanglion14.3
FetalThyroid7.45
Fetalbrain8.4
Fetalliver6.15
Fetallung120.5
GlobusPallidus5.75
Heart10.8
Hypothalamus22.25
Kidney89.4
Leukemia_chronicMyelogenousK-56219.05
Leukemia_promyelocytic-HL-606.4
Leukemialymphoblastic(MOLT-4)13.2
Liver14.4
Lung252.65
Lymphnode75.15
Lymphoma_burkitts(Daudi)9.45
Lymphoma_burkitts(Raji)24.75
MedullaOblongata6.9
OccipitalLobe6.8
OlfactoryBulb202.9
Ovary16.4
Pancreas162.45
PancreaticIslet95.5
ParietalLobe8.1
Pituitary9.1
Placenta524.45
Pons7.5
PrefrontalCortex9.8
Prostate55.5
Salivarygland16.3
SkeletalMuscle17.55
Skin41.9
SmoothMuscle8.95
Spinalcord46.2
SubthalamicNucleus6.8
SuperiorCervicalGanglion92.95
TemporalLobe7
Testis6.3
TestisGermCell28.9
TestisIntersitial22.55
TestisLeydigCell7.7
TestisSeminiferousTubule8.65
Thalamus7.35
Thymus32.65
Thyroid110.2
Tongue13.3
Tonsil8.3
Trachea199.9
TrigeminalGanglion57.6
Uterus94.4
UterusCorpus88.2
WholeBlood8.05
Wholebrain9.85
colon7.8
pineal_day23.24
pineal_night30.1
retina79.9
small_intestine9.8
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_32_P108567
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.03 ± 0.98
Basal Forebrain1.57 ± 0.19
Basal Part of Pons1.34 ± 0.4
Cerebellar Cortex1.44 ± 0.63
Cerebellar Nuclei1.87 ± 0.69
Claustrum2.44 ± 0.82
Epithalamus1.31 ± 0.66
Frontal Lobe1.42 ± 0.57
Globus Pallidus2.18 ± 0.34
Hypothalamus1.64 ± 0.62
Insula1.51 ± 0.53
Limbic Lobe1.6 ± 0.58
Mesencephalon1.74 ± 0.66
Myelencephalon1.63 ± 0.62
Occipital Lobe1.65 ± 0.58
Parietal Lobe1.61 ± 0.68
Pontine Tegmentum1.62 ± 0.63
Striatum1.74 ± 0.48
Subthalamus1.74 ± 0.61
Temporal Lobe1.48 ± 0.55
Thalamus1.56 ± 0.56
White Matter2.34 ± 0.52
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Atf3CBCerebellum3.03
3.81
Atf3CTXCerebral cortex1.34
1.08
Atf3HIPHippocampal region2.43
2.56
Atf3HPFHippocampal formation3.13
2.84
Atf3HYHypothalamus1.6
1.23
Atf3LSXLateral septal complex2.15
2
Atf3MBMidbrain2.36
2.9
Atf3MYMedulla4.63
4.83
Atf3OLFOlfactory bulb9.02
6.67
Atf3PPons4.39
4.78
Atf3PALPallidum0.73
0.55
Atf3RHPRetrohippocampal region4.02
2.95
Atf3sAMYStriatum-like amygdalar nuclei1.26
1.12
Atf3STRStriatum1.43
1.36
Atf3STRdStriatum dorsal region0.64
0.65
Atf3STRvStriatum ventral region3.67
3.17
Atf3THThalamus0.8
0.73
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved