AutismKB 2.0

Annotation Detail for NCF2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:NCF2 ( FLJ93058,NCF-2,NOXA2,P67-PHOX,P67PHOX )
Gene Full Name: neutrophil cytosolic factor 2
Band: 1q25.3
Quick LinksEntrez ID:4688; OMIM: 608515; Uniprot ID:NCF2_HUMAN; ENSEMBL ID: ENSG00000116701; HGNC ID: 7661
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus8 / 56401214
neonate25 / 31097803
infant0 / 236200 
juvenile0 / 555560 
adult70 / 193912136
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor2 / 9417821
cervical tumor0 / 343660 
chondrosarcoma6 / 8282372
colorectal tumor3 / 11424626
esophageal tumor2 / 17290115
gastrointestinal tumor0 / 1193690 
germ cell tumor4 / 26384515
glioma2 / 10688318
head and neck tumor0 / 1363020 
kidney tumor1 / 6895914
leukemia37 / 95842386
liver tumor2 / 9635920
lung tumor1 / 1031279
lymphoma1 / 7175513
non-neoplasia23 / 97250236
normal263 / 336030778
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood162 / 1234781311
bone1 / 7165513
bone marrow1 / 4880120
brain12 / 110098910
cervix1 / 4817120
connective tissue33 / 149255221
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus2 / 2020998
eye5 / 21105423
heart0 / 896260 
intestine8 / 23447234
kidney3 / 21177714
larynx0 / 241450 
liver4 / 20774319
lung29 / 33697486
lymph1 / 4427022
lymph node3 / 9161032
mammary gland4 / 15327126
mouth0 / 670520 
muscle0 / 1077150 
nerve0 / 157680 
ovary1 / 1020519
pancreas1 / 2148124
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta17 / 28082560
prostate0 / 1893450 
salivary gland0 / 201550 
skin1 / 2105744
spleen24 / 53952444
stomach0 / 966190 
testis1 / 3304423
thymus3 / 8113136
thyroid1 / 4747321
tonsil0 / 169990 
trachea2 / 5241338
umbilical cord0 / 136800 
uterus1 / 2328784
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 209949_at
Cell line Expression level Expression bar
721_B_lymphoblasts223.45
Adipocyte4.75
AdrenalCortex5.1
Adrenalgland4.1
Amygdala4.95
Appendix5.3
AtrioventricularNode4.05
BDCA4+_DentriticCells693.5
Bonemarrow343.15
BronchialEpithelialCells13.25
CD105+_Endothelial11.65
CD14+_Monocytes2619.1
CD19+_BCells(neg._sel.)7.25
CD33+_Myeloid3085.15
CD34+8.2
CD4+_Tcells5.05
CD56+_NKCells172.8
CD71+_EarlyErythroid4.55
CD8+_Tcells4.55
CardiacMyocytes6.2
Caudatenucleus4.35
Cerebellum3.9
CerebellumPeduncles5.45
CiliaryGanglion3.6
CingulateCortex4.9
Colorectaladenocarcinoma4.75
DorsalRootGanglion3.8
FetalThyroid4.6
Fetalbrain4.8
Fetalliver4.2
Fetallung6.55
GlobusPallidus3.6
Heart6.15
Hypothalamus5.25
Kidney4
Leukemia_chronicMyelogenousK-5624.35
Leukemia_promyelocytic-HL-604.25
Leukemialymphoblastic(MOLT-4)3.8
Liver6.35
Lung96.6
Lymphnode7.4
Lymphoma_burkitts(Daudi)6.15
Lymphoma_burkitts(Raji)6.75
MedullaOblongata4.4
OccipitalLobe4.3
OlfactoryBulb3.8
Ovary3.25
Pancreas3.85
PancreaticIslet5.15
ParietalLobe5.1
Pituitary5.65
Placenta10.65
Pons4.55
PrefrontalCortex5.8
Prostate5.55
Salivarygland3.8
SkeletalMuscle5.55
Skin3.95
SmoothMuscle5.45
Spinalcord5.15
SubthalamicNucleus4.4
SuperiorCervicalGanglion5.65
TemporalLobe4.4
Testis4.1
TestisGermCell4.05
TestisIntersitial3.95
TestisLeydigCell4.8
TestisSeminiferousTubule4.1
Thalamus4.9
Thymus3.8
Thyroid5.85
Tongue4.8
Tonsil4.7
Trachea4.05
TrigeminalGanglion5.05
Uterus3.9
UterusCorpus4.25
WholeBlood3531.75
Wholebrain3.85
colon4.8
pineal_day5.84
pineal_night5.72
retina5.85
small_intestine4.6
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P138194
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala2.27 ± 1.1
Basal Forebrain1.91 ± 0.58
Basal Part of Pons1.66 ± 0.46
Cerebellar Cortex1.46 ± 0.51
Cerebellar Nuclei2.6 ± 0.71
Claustrum2.68 ± 0.93
Epithalamus1.79 ± 0.72
Frontal Lobe1.65 ± 0.72
Globus Pallidus3.41 ± 0.61
Hypothalamus1.8 ± 0.71
Insula1.79 ± 0.96
Limbic Lobe1.76 ± 0.63
Mesencephalon2 ± 0.82
Myelencephalon1.88 ± 0.83
Occipital Lobe1.73 ± 0.45
Parietal Lobe1.94 ± 1.09
Pontine Tegmentum1.87 ± 0.77
Striatum2.16 ± 0.66
Subthalamus1.85 ± 0.68
Temporal Lobe1.81 ± 0.7
Thalamus1.79 ± 0.8
White Matter3.18 ± 0.92
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ncf2CBCerebellum13.52
18.97
Ncf2CTXCerebral cortex27.53
23
Ncf2HIPHippocampal region9.47
13.26
Ncf2HPFHippocampal formation7.62
9.35
Ncf2HYHypothalamus24.23
25.88
Ncf2LSXLateral septal complex4.75
5.08
Ncf2MBMidbrain6.88
7.97
Ncf2MYMedulla21.47
26.52
Ncf2OLFOlfactory bulb26.56
25.43
Ncf2PPons10.64
13
Ncf2PALPallidum15.88
17.76
Ncf2RHPRetrohippocampal region3.76
2.94
Ncf2sAMYStriatum-like amygdalar nuclei10.28
7.67
Ncf2STRStriatum11.79
9.85
Ncf2STRdStriatum dorsal region9.63
7.6
Ncf2STRvStriatum ventral region23.4
20.09
Ncf2THThalamus25.23
28.53
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00034633 23 302 324 HPQQQPQEESSPQSDIPAPPSSK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved