AutismKB 2.0

Annotation Detail for NDUFB2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:NDUFB2 ( AGGG,CI-AGGG,MGC70788 )
Gene Full Name: NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
Band: 7q34
Quick LinksEntrez ID:4708; OMIM: 603838; Uniprot ID:NDUB2_HUMAN; ENSEMBL ID: ENSG00000090266; HGNC ID: 7697
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst2 / 6231932
fetus29 / 56401251
neonate3 / 3109796
infant0 / 236200 
juvenile1 / 5555617
adult128 / 193912166
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor4 / 9417842
cervical tumor1 / 3436629
chondrosarcoma2 / 8282324
colorectal tumor0 / 1142460 
esophageal tumor1 / 1729057
gastrointestinal tumor12 / 119369100
germ cell tumor5 / 26384518
glioma14 / 106883130
head and neck tumor8 / 13630258
kidney tumor9 / 68959130
leukemia3 / 9584231
liver tumor6 / 9635962
lung tumor3 / 10312729
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal220 / 336030765
ovarian tumor3 / 7668239
pancreatic tumor5 / 10461647
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer6 / 10268058
retinoblastoma0 / 463560 
skin tumor2 / 12494916
soft tissue/muscle tissue tumor9 / 12519171
uterine tumor11 / 90257121
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland1 / 3319730
ascites2 / 4001549
bladder1 / 2975733
blood5 / 12347840
bone1 / 7165513
bone marrow1 / 4880120
brain61 / 110098955
cervix1 / 4817120
connective tissue12 / 14925580
ear0 / 162120 
embryonic tissue5 / 21572223
esophagus1 / 2020949
eye11 / 21105452
heart13 / 89626145
intestine12 / 23447251
kidney16 / 21177775
larynx2 / 2414582
liver16 / 20774377
lung8 / 33697423
lymph0 / 442700 
lymph node0 / 916100 
mammary gland7 / 15327145
mouth1 / 6705214
muscle22 / 107715204
nerve0 / 157680 
ovary4 / 10205139
pancreas9 / 21481241
parathyroid0 / 205390 
pharynx3 / 4132872
pituitary gland3 / 16585180
placenta12 / 28082542
prostate12 / 18934563
salivary gland0 / 201550 
skin4 / 21057418
spleen0 / 539520 
stomach9 / 9661993
testis11 / 33044233
thymus1 / 8113112
thyroid9 / 47473189
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord3 / 13680219
uterus23 / 23287898
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 218200_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts1271.5
Adipocyte770.8
AdrenalCortex372.8
Adrenalgland450.7
Amygdala952.7
Appendix290.7
AtrioventricularNode86.45
BDCA4+_DentriticCells1151.15
Bonemarrow256.65
BronchialEpithelialCells880.45
CD105+_Endothelial894.85
CD14+_Monocytes1544.45
CD19+_BCells(neg._sel.)1006.35
CD33+_Myeloid1670.1
CD34+1655.75
CD4+_Tcells901
CD56+_NKCells2025.95
CD71+_EarlyErythroid520.7
CD8+_Tcells729.65
CardiacMyocytes620.15
Caudatenucleus798.5
Cerebellum754.75
CerebellumPeduncles1242.85
CiliaryGanglion110.05
CingulateCortex734.25
Colorectaladenocarcinoma671.3
DorsalRootGanglion199.75
FetalThyroid1379.75
Fetalbrain429.1
Fetalliver150.5
Fetallung355.2
GlobusPallidus410.1
Heart4751.25
Hypothalamus1367.8
Kidney679.1
Leukemia_chronicMyelogenousK-562450.5
Leukemia_promyelocytic-HL-60636.05
Leukemialymphoblastic(MOLT-4)677.55
Liver921.7
Lung1028.4
Lymphnode352.25
Lymphoma_burkitts(Daudi)877.15
Lymphoma_burkitts(Raji)511.65
MedullaOblongata779.4
OccipitalLobe784.55
OlfactoryBulb412.65
Ovary194.9
Pancreas290.9
PancreaticIslet526.95
ParietalLobe718.35
Pituitary592.35
Placenta431.6
Pons629.05
PrefrontalCortex691.7
Prostate1193.9
Salivarygland381.85
SkeletalMuscle476.8
Skin155.55
SmoothMuscle986.8
Spinalcord939.05
SubthalamicNucleus596.25
SuperiorCervicalGanglion134.05
TemporalLobe941.35
Testis554.1
TestisGermCell470.5
TestisIntersitial428.9
TestisLeydigCell293.35
TestisSeminiferousTubule309
Thalamus1216.6
Thymus550.45
Thyroid2161.65
Tongue668.45
Tonsil441.95
Trachea305.55
TrigeminalGanglion101.2
Uterus531
UterusCorpus227.5
WholeBlood371.25
Wholebrain2402.2
colon877.5
pineal_day2680.54
pineal_night2467.94
retina1165.425
small_intestine530.85
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_5784_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala12.45 ± 0.47
Basal Forebrain12.61 ± 0.21
Basal Part of Pons13.07 ± 0.28
Cerebellar Cortex12.84 ± 0.41
Cerebellar Nuclei13.01 ± 0.38
Claustrum12.15 ± 0.78
Epithalamus12.59 ± 0.25
Frontal Lobe12.96 ± 0.36
Globus Pallidus12.95 ± 0.27
Hypothalamus13.12 ± 0.13
Insula12.93 ± 0.3
Limbic Lobe12.35 ± 0.67
Mesencephalon12.63 ± 0.53
Myelencephalon12.67 ± 0.52
Occipital Lobe12.01 ± 0.6
Parietal Lobe12.73 ± 0.47
Pontine Tegmentum12.84 ± 0.41
Striatum12.44 ± 0.47
Subthalamus13.24 ± 0.21
Temporal Lobe12.87 ± 0.41
Thalamus12.78 ± 0.39
White Matter12.71 ± 0.34
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Ndufb2CBCerebellum16.92
24.59
Ndufb2CTXCerebral cortex21.04
16.63
Ndufb2HIPHippocampal region15.49
17.05
Ndufb2HPFHippocampal formation15.25
15.25
Ndufb2HYHypothalamus8.42
8.56
Ndufb2LSXLateral septal complex2.51
1.59
Ndufb2MBMidbrain10.96
12.13
Ndufb2MYMedulla19.91
27.73
Ndufb2OLFOlfactory bulb15.72
13.38
Ndufb2PPons14.62
19.91
Ndufb2PALPallidum12.3
13.34
Ndufb2RHPRetrohippocampal region14.65
12.41
Ndufb2sAMYStriatum-like amygdalar nuclei10.63
7.5
Ndufb2STRStriatum8.11
6.58
Ndufb2STRdStriatum dorsal region7.57
6.36
Ndufb2STRvStriatum ventral region11.16
8.64
Ndufb2THThalamus15.66
15.48
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
NDUB2_HUMAN_34 10 34 43 AGGGVHIEPR PRIDE
NDUB2_HUMAN_44 9 44 52 YRQFPQLTR PRIDE
NDUB2_HUMAN_46 7 46 52 QFPQLTR PRIDE
PAp00040343 33 73 105 FWHDSEEVLGHFPYPDPSQWTDEELGIPPDDED Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved