AutismKB 2.0

Annotation Detail for GIMAP6


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:GIMAP6 ( DKFZp686A01175,FLJ22690,IAN6,hIAN2 )
Gene Full Name: GTPase, IMAP family member 6
Band: 7q36.1
Quick LinksEntrez ID:474344; OMIM: NA; Uniprot ID:GIMA6_HUMAN; ENSEMBL ID: ENSG00000133561; HGNC ID: 21918
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus8 / 56401214
neonate1 / 3109732
infant0 / 236200 
juvenile1 / 5555617
adult34 / 193912117
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor1 / 9417810
cervical tumor1 / 3436629
chondrosarcoma1 / 8282312
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor2 / 11936916
germ cell tumor4 / 26384515
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor3 / 6895943
leukemia3 / 9584231
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma1 / 7175513
non-neoplasia12 / 97250123
normal110 / 336030732
ovarian tumor0 / 766820 
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood11 / 12347889
bone1 / 7165513
bone marrow0 / 488010 
brain27 / 110098924
cervix1 / 4817120
connective tissue13 / 14925587
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye2 / 2110549
heart2 / 8962622
intestine2 / 2344728
kidney6 / 21177728
larynx0 / 241450 
liver0 / 2077430 
lung9 / 33697426
lymph0 / 442700 
lymph node1 / 9161010
mammary gland3 / 15327119
mouth2 / 6705229
muscle1 / 1077159
nerve0 / 157680 
ovary0 / 1020510 
pancreas1 / 2148124
parathyroid1 / 2053948
pharynx1 / 4132824
pituitary gland0 / 165850 
placenta22 / 28082578
prostate2 / 18934510
salivary gland0 / 201550 
skin0 / 2105740 
spleen12 / 53952222
stomach2 / 9661920
testis4 / 33044212
thymus20 / 81131246
thyroid0 / 474730 
tonsil0 / 169990 
trachea13 / 52413248
umbilical cord1 / 1368073
uterus5 / 23287821
vascular14 / 51780270
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 219777_at
Cell line Expression level Expression bar
721_B_lymphoblasts211.15
Adipocyte8.6
AdrenalCortex11.55
Adrenalgland10.95
Amygdala10.45
Appendix11.2
AtrioventricularNode10.05
BDCA4+_DentriticCells17.8
Bonemarrow11.1
BronchialEpithelialCells8.65
CD105+_Endothelial9.55
CD14+_Monocytes378.9
CD19+_BCells(neg._sel.)9.25
CD33+_Myeloid155.5
CD34+13.2
CD4+_Tcells855.4
CD56+_NKCells914.6
CD71+_EarlyErythroid8.9
CD8+_Tcells752.15
CardiacMyocytes17.5
Caudatenucleus8.15
Cerebellum7.5
CerebellumPeduncles11.15
CiliaryGanglion8.2
CingulateCortex9.6
Colorectaladenocarcinoma9.2
DorsalRootGanglion8.2
FetalThyroid10.85
Fetalbrain8.6
Fetalliver8.25
Fetallung13
GlobusPallidus7.7
Heart28.9
Hypothalamus10.15
Kidney8.7
Leukemia_chronicMyelogenousK-5628.05
Leukemia_promyelocytic-HL-608
Leukemialymphoblastic(MOLT-4)11.3
Liver15.5
Lung193.15
Lymphnode81.3
Lymphoma_burkitts(Daudi)12
Lymphoma_burkitts(Raji)14.7
MedullaOblongata7.8
OccipitalLobe8.2
OlfactoryBulb7.1
Ovary7
Pancreas7.85
PancreaticIslet10.5
ParietalLobe10.35
Pituitary10.7
Placenta87.8
Pons9.15
PrefrontalCortex10.1
Prostate11.3
Salivarygland8.7
SkeletalMuscle13.7
Skin9.6
SmoothMuscle10
Spinalcord10.3
SubthalamicNucleus8.7
SuperiorCervicalGanglion15.35
TemporalLobe8.8
Testis7.7
TestisGermCell7.05
TestisIntersitial8.05
TestisLeydigCell9.4
TestisSeminiferousTubule7.65
Thalamus10.25
Thymus42.3
Thyroid38.35
Tongue10.65
Tonsil14.6
Trachea7.75
TrigeminalGanglion11.9
Uterus31.5
UterusCorpus11.6
WholeBlood394.65
Wholebrain7.7
colon22.85
pineal_day11.26
pineal_night11.46
retina20.925
small_intestine98.7
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P145631
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala3.86 ± 0.51
Basal Forebrain4.04 ± 0.52
Basal Part of Pons4.13 ± 0.46
Cerebellar Cortex3.62 ± 0.5
Cerebellar Nuclei5.05 ± 0.53
Claustrum3.71 ± 0.68
Epithalamus3.9 ± 0.85
Frontal Lobe4.15 ± 0.6
Globus Pallidus5.27 ± 0.35
Hypothalamus3.6 ± 0.67
Insula4.05 ± 0.55
Limbic Lobe3.94 ± 0.73
Mesencephalon4.37 ± 0.69
Myelencephalon4.34 ± 0.65
Occipital Lobe4.55 ± 0.68
Parietal Lobe3.97 ± 0.69
Pontine Tegmentum4.18 ± 0.71
Striatum5.17 ± 0.51
Subthalamus4.38 ± 0.43
Temporal Lobe4.12 ± 0.49
Thalamus4.57 ± 0.59
White Matter4.28 ± 1.12
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Gimap6CBCerebellum0.42
1.18
Gimap6CTXCerebral cortex1.84
1.52
Gimap6HIPHippocampal region0.89
0.9
Gimap6HPFHippocampal formation0.96
0.96
Gimap6HYHypothalamus0.11
0.13
Gimap6LSXLateral septal complex0
0
Gimap6MBMidbrain0.49
1.18
Gimap6MYMedulla0.16
0.41
Gimap6OLFOlfactory bulb1.83
2.51
Gimap6PPons0.3
1.07
Gimap6PALPallidum0.04
0.02
Gimap6RHPRetrohippocampal region1.11
1.11
Gimap6sAMYStriatum-like amygdalar nuclei0.87
0.57
Gimap6STRStriatum0.24
0.29
Gimap6STRdStriatum dorsal region0.19
0.31
Gimap6STRvStriatum ventral region0.25
0.16
Gimap6THThalamus0.15
0.13
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved