AutismKB 2.0

Annotation Detail for NELL2


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:NELL2 ( NRP2 )
Gene Full Name: NEL-like 2 (chicken)
Band: 12q12
Quick LinksEntrez ID:4753; OMIM: 602320; Uniprot ID:NELL2_HUMAN; ENSEMBL ID: ENSG00000184613; HGNC ID: 7751
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body3 / 7076142
blastocyst2 / 6231932
fetus364 / 564012645
neonate0 / 310970 
infant1 / 2362042
juvenile9 / 55556161
adult210 / 1939121108
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor1 / 9417810
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor7 / 11936958
germ cell tumor99 / 263845375
glioma5 / 10688346
head and neck tumor23 / 136302168
kidney tumor4 / 6895958
leukemia2 / 9584220
liver tumor0 / 963590 
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal720 / 3360307214
ovarian tumor0 / 766820 
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS12 / 12568095
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor3 / 12519123
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder1 / 2975733
blood4 / 12347832
bone2 / 7165527
bone marrow2 / 4880140
brain675 / 1100989613
cervix0 / 481710 
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue11 / 21572250
esophagus0 / 202090 
eye24 / 211054113
heart1 / 8962611
intestine8 / 23447234
kidney4 / 21177718
larynx0 / 241450 
liver0 / 2077430 
lung3 / 3369748
lymph0 / 442700 
lymph node0 / 916100 
mammary gland3 / 15327119
mouth11 / 67052164
muscle3 / 10771527
nerve2 / 15768126
ovary0 / 1020510 
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland5 / 16585301
placenta0 / 2808250 
prostate5 / 18934526
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach0 / 966190 
testis87 / 330442263
thymus0 / 811310 
thyroid11 / 47473231
tonsil0 / 169990 
trachea4 / 5241376
umbilical cord0 / 136800 
uterus1 / 2328784
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203413_at
Cell line Expression level Expression bar
721_B_lymphoblasts9.25
Adipocyte17
AdrenalCortex24.7
Adrenalgland24.85
Amygdala1612.35
Appendix28.8
AtrioventricularNode19.35
BDCA4+_DentriticCells7.85
Bonemarrow31.45
BronchialEpithelialCells16.25
CD105+_Endothelial11.15
CD14+_Monocytes5.7
CD19+_BCells(neg._sel.)15.15
CD33+_Myeloid9.1
CD34+7.7
CD4+_Tcells1307.7
CD56+_NKCells21.8
CD71+_EarlyErythroid11.85
CD8+_Tcells1519.2
CardiacMyocytes34.2
Caudatenucleus254.2
Cerebellum69.55
CerebellumPeduncles153.3
CiliaryGanglion21.85
CingulateCortex541.25
Colorectaladenocarcinoma209.9
DorsalRootGanglion16.9
FetalThyroid21.95
Fetalbrain2217.3
Fetalliver17.45
Fetallung12.05
GlobusPallidus470.85
Heart33.5
Hypothalamus476.05
Kidney16.9
Leukemia_chronicMyelogenousK-56213.5
Leukemia_promyelocytic-HL-6014.75
Leukemialymphoblastic(MOLT-4)11.25
Liver34.4
Lung16.55
Lymphnode112.75
Lymphoma_burkitts(Daudi)37.8
Lymphoma_burkitts(Raji)28.8
MedullaOblongata425.5
OccipitalLobe801.65
OlfactoryBulb13
Ovary12.6
Pancreas36.15
PancreaticIslet20
ParietalLobe589.35
Pituitary569.25
Placenta11.1
Pons245.85
PrefrontalCortex1109.2
Prostate30.55
Salivarygland17.15
SkeletalMuscle28.35
Skin22.1
SmoothMuscle15.8
Spinalcord60.85
SubthalamicNucleus662.95
SuperiorCervicalGanglion35.45
TemporalLobe542.6
Testis12.95
TestisGermCell13
TestisIntersitial13.6
TestisLeydigCell16
TestisSeminiferousTubule10.85
Thalamus340.25
Thymus12.35
Thyroid27.55
Tongue25.65
Tonsil19.9
Trachea20.25
TrigeminalGanglion20.15
Uterus15.75
UterusCorpus18.65
WholeBlood64.7
Wholebrain626.35
colon17.75
pineal_day438.44
pineal_night275.6
retina213.65
small_intestine36.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P10025
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala10.44 ± 0.75
Basal Forebrain8.83 ± 0.55
Basal Part of Pons10.09 ± 0.32
Cerebellar Cortex10.13 ± 0.2
Cerebellar Nuclei8.25 ± 0.65
Claustrum10.71 ± 0.37
Epithalamus10.54 ± 0.67
Frontal Lobe10.54 ± 0.65
Globus Pallidus7.15 ± 0.98
Hypothalamus9.98 ± 0.47
Insula10.47 ± 1.01
Limbic Lobe11.05 ± 0.73
Mesencephalon9.92 ± 0.9
Myelencephalon10 ± 0.92
Occipital Lobe9.82 ± 0.72
Parietal Lobe10.19 ± 0.75
Pontine Tegmentum10.1 ± 0.85
Striatum8.98 ± 1.3
Subthalamus8.43 ± 0.88
Temporal Lobe10.69 ± 0.49
Thalamus9.81 ± 0.71
White Matter7.42 ± 0.94
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Nell2CBCerebellum96.97
100
Nell2CTXCerebral cortex100
100
Nell2HIPHippocampal region100
100
Nell2HPFHippocampal formation100
100
Nell2HYHypothalamus95.06
100
Nell2LSXLateral septal complex76.93
93.36
Nell2MBMidbrain94.78
100
Nell2MYMedulla57.66
93.21
Nell2OLFOlfactory bulb100
100
Nell2PPons68.46
97.13
Nell2PALPallidum60.66
87.7
Nell2RHPRetrohippocampal region100
100
Nell2sAMYStriatum-like amygdalar nuclei100
100
Nell2STRStriatum100
100
Nell2STRdStriatum dorsal region100
100
Nell2STRvStriatum ventral region100
100
Nell2THThalamus100
100
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00137386 9 79 87 AFLFQDTPR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved