AutismKB 2.0

Annotation Detail for NFIL3


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Basic Information Top
Gene Symbol:NFIL3 ( E4BP4,IL3BP1,NF-IL3A,NFIL3A )
Gene Full Name: nuclear factor, interleukin 3 regulated
Band: 9q22.31
Quick LinksEntrez ID:4783; OMIM: 605327; Uniprot ID:NFIL3_HUMAN; ENSEMBL ID: ENSG00000165030; HGNC ID: 7787
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus18 / 56401231
neonate0 / 310970 
infant0 / 236200 
juvenile3 / 5555653
adult53 / 193912127
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma1 / 1747557
breast (mammary gland) tumor2 / 9417821
cervical tumor1 / 3436629
chondrosarcoma7 / 8282384
colorectal tumor0 / 1142460 
esophageal tumor1 / 1729057
gastrointestinal tumor4 / 11936933
germ cell tumor9 / 26384534
glioma4 / 10688337
head and neck tumor0 / 1363020 
kidney tumor4 / 6895958
leukemia1 / 9584210
liver tumor3 / 9635931
lung tumor4 / 10312738
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal81 / 336030724
ovarian tumor2 / 7668226
pancreatic tumor3 / 10461628
primitive neuroectodermal tumor of the CNS2 / 12568015
prostate cancer2 / 10268019
retinoblastoma0 / 463560 
skin tumor1 / 1249498
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites1 / 4001524
bladder0 / 297570 
blood2 / 12347816
bone4 / 7165555
bone marrow0 / 488010 
brain13 / 110098911
cervix1 / 4817120
connective tissue5 / 14925533
ear0 / 162120 
embryonic tissue0 / 2157220 
esophagus1 / 2020949
eye1 / 2110544
heart6 / 8962666
intestine2 / 2344728
kidney17 / 21177780
larynx1 / 2414541
liver9 / 20774343
lung14 / 33697441
lymph0 / 442700 
lymph node1 / 9161010
mammary gland4 / 15327126
mouth0 / 670520 
muscle1 / 1077159
nerve1 / 1576863
ovary2 / 10205119
pancreas6 / 21481227
parathyroid1 / 2053948
pharynx0 / 413280 
pituitary gland2 / 16585120
placenta11 / 28082539
prostate6 / 18934531
salivary gland0 / 201550 
skin3 / 21057414
spleen0 / 539520 
stomach2 / 9661920
testis6 / 33044218
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus6 / 23287825
vascular1 / 5178019
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 203574_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.55
Adipocyte190.15
AdrenalCortex164
Adrenalgland34.15
Amygdala11.45
Appendix32.35
AtrioventricularNode9.85
BDCA4+_DentriticCells77.4
Bonemarrow28.35
BronchialEpithelialCells22.35
CD105+_Endothelial9.4
CD14+_Monocytes450.15
CD19+_BCells(neg._sel.)12.2
CD33+_Myeloid500.15
CD34+15.4
CD4+_Tcells8.55
CD56+_NKCells414.3
CD71+_EarlyErythroid7.9
CD8+_Tcells8.75
CardiacMyocytes12.65
Caudatenucleus8.45
Cerebellum7.35
CerebellumPeduncles9
CiliaryGanglion34.6
CingulateCortex8.6
Colorectaladenocarcinoma9.8
DorsalRootGanglion7.4
FetalThyroid9.7
Fetalbrain56
Fetalliver9.75
Fetallung205.35
GlobusPallidus5.55
Heart15.7
Hypothalamus11.75
Kidney6.65
Leukemia_chronicMyelogenousK-56210.8
Leukemia_promyelocytic-HL-609.45
Leukemialymphoblastic(MOLT-4)7.05
Liver13.9
Lung128.7
Lymphnode10.2
Lymphoma_burkitts(Daudi)14.15
Lymphoma_burkitts(Raji)13.2
MedullaOblongata8.45
OccipitalLobe5.55
OlfactoryBulb59.7
Ovary117.7
Pancreas26.7
PancreaticIslet134.15
ParietalLobe7.5
Pituitary10.85
Placenta75
Pons9.2
PrefrontalCortex13.05
Prostate77.05
Salivarygland10.5
SkeletalMuscle14.15
Skin9.05
SmoothMuscle15.2
Spinalcord11.3
SubthalamicNucleus6.25
SuperiorCervicalGanglion15.15
TemporalLobe10
Testis25.15
TestisGermCell20.45
TestisIntersitial9.2
TestisLeydigCell11.35
TestisSeminiferousTubule16.15
Thalamus8.1
Thymus9.3
Thyroid15.1
Tongue7.25
Tonsil7.95
Trachea14.7
TrigeminalGanglion11.75
Uterus101.95
UterusCorpus33.8
WholeBlood553.85
Wholebrain8.9
colon12.9
pineal_day25.58
pineal_night35.02
retina34.875
small_intestine26.65
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16274_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.11 ± 0.84
Basal Forebrain8.98 ± 0.25
Basal Part of Pons8.97 ± 0.56
Cerebellar Cortex8.46 ± 0.44
Cerebellar Nuclei9.06 ± 0.63
Claustrum9.45 ± 0.83
Epithalamus8.52 ± 0.36
Frontal Lobe8.81 ± 0.63
Globus Pallidus9.46 ± 0.45
Hypothalamus8.99 ± 0.45
Insula8.65 ± 0.44
Limbic Lobe8.96 ± 0.68
Mesencephalon9.14 ± 0.58
Myelencephalon8.96 ± 0.64
Occipital Lobe9.07 ± 0.66
Parietal Lobe8.92 ± 0.62
Pontine Tegmentum8.79 ± 0.51
Striatum9.2 ± 0.72
Subthalamus8.74 ± 0.4
Temporal Lobe8.79 ± 0.65
Thalamus9.02 ± 0.56
White Matter9.05 ± 0.29
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Nfil3CBCerebellum25.58
35.47
Nfil3CTXCerebral cortex11.29
8.39
Nfil3HIPHippocampal region10.64
11.81
Nfil3HPFHippocampal formation10.11
10.13
Nfil3HYHypothalamus3.1
2.48
Nfil3LSXLateral septal complex4.14
3.57
Nfil3MBMidbrain4.28
4.3
Nfil3MYMedulla5.63
7.04
Nfil3OLFOlfactory bulb20.61
17.79
Nfil3PPons5.79
6.96
Nfil3PALPallidum3.29
2.61
Nfil3RHPRetrohippocampal region9.6
8.35
Nfil3sAMYStriatum-like amygdalar nuclei3.27
2.39
Nfil3STRStriatum2.88
2.28
Nfil3STRdStriatum dorsal region1.93
1.61
Nfil3STRvStriatum ventral region5.18
3.66
Nfil3THThalamus3.95
3.38
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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