Annotation Detail for NFIX
Basic Information Top
| Gene Symbol: | NFIX ( NF1A ) |
|---|---|
| Gene Full Name: | nuclear factor I/X (CCAAT-binding transcription factor) |
| Band: | 19p13.13 |
| Quick Links | Entrez ID:4784; OMIM: 164005; Uniprot ID:NFIX_HUMAN; ENSEMBL ID: ENSG00000008441; HGNC ID: 7788 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.257970
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 1 / 70761 | 14 |  |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 52 / 564012 | 92 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 100 / 1939121 | 51 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 3 / 17475 | 171 | |
| breast (mammary gland) tumor | 2 / 94178 | 21 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 17 / 82823 | 205 |  |
| colorectal tumor | 5 / 114246 | 43 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 2 / 119369 | 16 | |
| germ cell tumor | 3 / 263845 | 11 | |
| glioma | 29 / 106883 | 271 | |
| head and neck tumor | 7 / 136302 | 51 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 1 / 96359 | 10 |  |
| lung tumor | 8 / 103127 | 77 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 3 / 97250 | 30 | |
| normal | 126 / 3360307 | 37 | |
| ovarian tumor | 8 / 76682 | 104 | |
| pancreatic tumor | 2 / 104616 | 19 | |
| primitive neuroectodermal tumor of the CNS | 2 / 125680 | 15 | |
| prostate cancer | 15 / 102680 | 146 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 4 / 124949 | 32 | |
| soft tissue/muscle tissue tumor | 7 / 125191 | 55 | |
| uterine tumor | 5 / 90257 | 55 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 3 / 29757 | 100 | |
| blood | 0 / 123478 | 0 | |
| bone | 11 / 71655 | 153 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 74 / 1100989 | 67 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 13 / 149255 | 87 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 1 / 215722 | 4 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 14 / 211054 | 66 | |
| heart | 5 / 89626 | 55 | |
| intestine | 6 / 234472 | 25 | |
| kidney | 1 / 211777 | 4 | |
| larynx | 1 / 24145 | 41 | |
| liver | 1 / 207743 | 4 | |
| lung | 19 / 336974 | 56 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 7 / 153271 | 45 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 6 / 107715 | 55 | |
| nerve | 1 / 15768 | 63 | |
| ovary | 9 / 102051 | 88 | |
| pancreas | 2 / 214812 | 9 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 2 / 16585 | 120 | |
| placenta | 3 / 280825 | 10 | |
| prostate | 27 / 189345 | 142 | |
| salivary gland | 1 / 20155 | 49 | |
| skin | 8 / 210574 | 37 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 2 / 96619 | 20 | |
| testis | 5 / 330442 | 15 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 7 / 47473 | 147 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 14 / 232878 | 60 | |
| vascular | 0 / 51780 | 0 |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 209807_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 4.9 | |
| Adipocyte | 3.8 | |
| AdrenalCortex | 4 | |
| Adrenalgland | 3.2 | |
| Amygdala | 4.05 | |
| Appendix | 3.95 | |
| AtrioventricularNode | 2.95 | |
| BDCA4+_DentriticCells | 4.25 | |
| Bonemarrow | 3.9 | |
| BronchialEpithelialCells | 3.8 | |
| CD105+_Endothelial | 4.9 | |
| CD14+_Monocytes | 4.1 | |
| CD19+_BCells(neg._sel.) | 4.15 | |
| CD33+_Myeloid | 5 | |
| CD34+ | 4.95 | |
| CD4+_Tcells | 4.2 | |
| CD56+_NKCells | 4.6 | |
| CD71+_EarlyErythroid | 13.15 | |
| CD8+_Tcells | 3.75 | |
| CardiacMyocytes | 5.1 | |
| Caudatenucleus | 3.45 | |
| Cerebellum | 3.1 | |
| CerebellumPeduncles | 4.35 | |
| CiliaryGanglion | 2.7 | |
| CingulateCortex | 3.95 | |
| Colorectaladenocarcinoma | 9.05 | |
| DorsalRootGanglion | 2.95 | |
| FetalThyroid | 3.75 | |
| Fetalbrain | 3.85 | |
| Fetalliver | 3.35 | |
| Fetallung | 3.15 | |
| GlobusPallidus | 2.85 | |
| Heart | 6.65 | |
| Hypothalamus | 4.2 | |
| Kidney | 3.1 | |
| Leukemia_chronicMyelogenousK-562 | 3.5 | |
| Leukemia_promyelocytic-HL-60 | 3.4 | |
| Leukemialymphoblastic(MOLT-4) | 3.15 | |
| Liver | 5.1 | |
| Lung | 4.25 | |
| Lymphnode | 3.3 | |
| Lymphoma_burkitts(Daudi) | 4.9 | |
| Lymphoma_burkitts(Raji) | 5.45 | |
| MedullaOblongata | 3.5 | |
| OccipitalLobe | 3.45 | |
| OlfactoryBulb | 3.05 | |
| Ovary | 2.55 | |
| Pancreas | 3.1 | |
| PancreaticIslet | 4.1 | |
| ParietalLobe | 4.05 | |
| Pituitary | 4.5 | |
| Placenta | 4.05 | |
| Pons | 3.65 | |
| PrefrontalCortex | 4.85 | |
| Prostate | 4.55 | |
| Salivarygland | 3.1 | |
| SkeletalMuscle | 4.65 | |
| Skin | 2.95 | |
| SmoothMuscle | 4.35 | |
| Spinalcord | 4.15 | |
| SubthalamicNucleus | 3.55 | |
| SuperiorCervicalGanglion | 4.45 | |
| TemporalLobe | 3.5 | |
| Testis | 3.3 | |
| TestisGermCell | 3.25 | |
| TestisIntersitial | 3.25 | |
| TestisLeydigCell | 3.8 | |
| TestisSeminiferousTubule | 3.3 | |
| Thalamus | 3.9 | |
| Thymus | 3.05 | |
| Thyroid | 4.85 | |
| Tongue | 3.8 | |
| Tonsil | 3.75 | |
| Trachea | 3.2 | |
| TrigeminalGanglion | 3.95 | |
| Uterus | 3.2 | |
| UterusCorpus | 3.45 | |
| WholeBlood | 4.2 | |
| Wholebrain | 3.35 | |
| colon | 3.9 | |
| pineal_day | 4.88 | |
| pineal_night | 4.78 | |
| retina | 4.7 | |
| small_intestine | 3.75 | |
- Probe name: A_24_P858698
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 9.82 ± 0.54 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 10.37 ± 0.31 | |
| Basal Part of Pons | 10.73 ± 0.42 | |
| Cerebellar Cortex | 10.87 ± 0.44 | |
| Cerebellar Nuclei | 10.31 ± 0.67 | |
| Claustrum | 9.58 ± 0.7 | |
| Epithalamus | 10.95 ± 0.58 | |
| Frontal Lobe | 10.48 ± 0.48 | |
| Globus Pallidus | 11.11 ± 0.51 | |
| Hypothalamus | 9.71 ± 0.52 | |
| Insula | 10.2 ± 0.21 | |
| Limbic Lobe | 10.6 ± 0.51 | |
| Mesencephalon | 10.29 ± 0.51 | |
| Myelencephalon | 10.49 ± 0.53 | |
| Occipital Lobe | 10.87 ± 0.39 | |
| Parietal Lobe | 10.63 ± 0.42 | |
| Pontine Tegmentum | 10.27 ± 0.52 | |
| Striatum | 9.87 ± 0.48 | |
| Subthalamus | 9.85 ± 0.63 | |
| Temporal Lobe | 10.37 ± 0.38 | |
| Thalamus | 10.38 ± 0.42 | |
| White Matter | 11.88 ± 0.21 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Nfix | CB | Cerebellum | 78.56 | |
| 52.82 | | |||
| Nfix | CTX | Cerebral cortex | 96.24 | |
| 71.71 | | |||
| Nfix | HIP | Hippocampal region | 87.14 | |
| 100 | | |||
| Nfix | HPF | Hippocampal formation | 99.39 | |
| 100 | | |||
| Nfix | HY | Hypothalamus | 12.58 | |
| 7.67 | | |||
| Nfix | LSX | Lateral septal complex | 23.7 | |
| 16.43 | | |||
| Nfix | MB | Midbrain | 23.05 | |
| 15.27 | | |||
| Nfix | MY | Medulla | 21.25 | |
| 16.43 | | |||
| Nfix | OLF | Olfactory bulb | 40.69 | |
| 28.32 | | |||
| Nfix | P | Pons | 37.69 | |
| 32.73 | | |||
| Nfix | PAL | Pallidum | 8.95 | |
| 5.99 | | |||
| Nfix | RHP | Retrohippocampal region | 100 | |
| 100 | | |||
| Nfix | sAMY | Striatum-like amygdalar nuclei | 16.96 | |
| 11.37 | | |||
| Nfix | STR | Striatum | 18.29 | |
| 13.46 | | |||
| Nfix | STRd | Striatum dorsal region | 18.82 | |
| 15.03 | | |||
| Nfix | STRv | Striatum ventral region | 13.21 | |
| 7.31 | | |||
| Nfix | TH | Thalamus | 15.62 | |
| 11.1 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00024884 | 21 | 402 | 422 | EFVQFVCSDGSGQATGQHSQR | Peptide Atlas |