AutismKB 2.0

Annotation Detail for NFYA


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Basic Information Top
Gene Symbol:NFYA ( CBF-A,CBF-B,FLJ11236,HAP2,NF-YA )
Gene Full Name: nuclear transcription factor Y, alpha
Band: 6p21.1
Quick LinksEntrez ID:4800; OMIM: 189903; Uniprot ID:NFYA_HUMAN; ENSEMBL ID: ENSG00000001167; HGNC ID: 7804
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body8 / 70761113
blastocyst2 / 6231932
fetus33 / 56401258
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult81 / 193912141
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor1 / 1279478
bladder carcinoma1 / 1747557
breast (mammary gland) tumor4 / 9417842
cervical tumor1 / 3436629
chondrosarcoma2 / 8282324
colorectal tumor3 / 11424626
esophageal tumor0 / 172900 
gastrointestinal tumor5 / 11936941
germ cell tumor10 / 26384537
glioma3 / 10688328
head and neck tumor2 / 13630214
kidney tumor0 / 689590 
leukemia4 / 9584241
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma0 / 717550 
non-neoplasia5 / 9725051
normal127 / 336030737
ovarian tumor3 / 7668239
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS5 / 12568039
prostate cancer2 / 10268019
retinoblastoma4 / 4635686
skin tumor1 / 1249498
soft tissue/muscle tissue tumor7 / 12519155
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland1 / 3319730
ascites0 / 400150 
bladder1 / 2975733
blood8 / 12347864
bone2 / 7165527
bone marrow1 / 4880120
brain41 / 110098937
cervix1 / 4817120
connective tissue6 / 14925540
ear2 / 16212123
embryonic tissue11 / 21572250
esophagus0 / 202090 
eye9 / 21105442
heart2 / 8962622
intestine9 / 23447238
kidney3 / 21177714
larynx0 / 241450 
liver1 / 2077434
lung8 / 33697423
lymph0 / 442700 
lymph node6 / 9161065
mammary gland10 / 15327165
mouth1 / 6705214
muscle3 / 10771527
nerve1 / 1576863
ovary2 / 10205119
pancreas5 / 21481223
parathyroid0 / 205390 
pharynx1 / 4132824
pituitary gland1 / 1658560
placenta7 / 28082524
prostate5 / 18934526
salivary gland0 / 201550 
skin1 / 2105744
spleen0 / 539520 
stomach3 / 9661931
testis25 / 33044275
thymus3 / 8113136
thyroid1 / 4747321
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus5 / 23287821
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204108_at
Cell line Expression level Expression bar
721_B_lymphoblasts30.75
Adipocyte8.45
AdrenalCortex10.4
Adrenalgland7.5
Amygdala8.85
Appendix10.75
AtrioventricularNode7.25
BDCA4+_DentriticCells19.2
Bonemarrow8.6
BronchialEpithelialCells8.9
CD105+_Endothelial8.85
CD14+_Monocytes10.95
CD19+_BCells(neg._sel.)14.65
CD33+_Myeloid19.15
CD34+25.65
CD4+_Tcells23.45
CD56+_NKCells10.4
CD71+_EarlyErythroid8.45
CD8+_Tcells20.5
CardiacMyocytes11.75
Caudatenucleus7.6
Cerebellum7.2
CerebellumPeduncles10.1
CiliaryGanglion6.65
CingulateCortex9.15
Colorectaladenocarcinoma8.7
DorsalRootGanglion9.35
FetalThyroid8.45
Fetalbrain10.35
Fetalliver7.55
Fetallung8.1
GlobusPallidus7.4
Heart11.25
Hypothalamus9.6
Kidney7.35
Leukemia_chronicMyelogenousK-5629.25
Leukemia_promyelocytic-HL-608.05
Leukemialymphoblastic(MOLT-4)44.35
Liver11.15
Lung8.15
Lymphnode8.6
Lymphoma_burkitts(Daudi)18.1
Lymphoma_burkitts(Raji)12.4
MedullaOblongata8
OccipitalLobe7.95
OlfactoryBulb7
Ovary9.4
Pancreas7.25
PancreaticIslet11.4
ParietalLobe9.3
Pituitary10.55
Placenta9.3
Pons8.8
PrefrontalCortex11.05
Prostate10.15
Salivarygland7.5
SkeletalMuscle12.15
Skin7
SmoothMuscle9.9
Spinalcord9.3
SubthalamicNucleus8.1
SuperiorCervicalGanglion13.9
TemporalLobe8.05
Testis9.5
TestisGermCell19.7
TestisIntersitial10.75
TestisLeydigCell13.5
TestisSeminiferousTubule19.35
Thalamus9.2
Thymus17
Thyroid10.1
Tongue12.25
Tonsil9
Trachea7.3
TrigeminalGanglion10.1
Uterus7.2
UterusCorpus8.8
WholeBlood21.1
Wholebrain6.8
colon7.75
pineal_day10.44
pineal_night9.48
retina10.275
small_intestine7.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P214425
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.09 ± 0.41
Basal Forebrain5.33 ± 0.31
Basal Part of Pons5.02 ± 0.23
Cerebellar Cortex5.06 ± 0.27
Cerebellar Nuclei5.13 ± 0.38
Claustrum4.95 ± 0.46
Epithalamus5.27 ± 0.37
Frontal Lobe5.03 ± 0.33
Globus Pallidus5.77 ± 0.48
Hypothalamus4.91 ± 0.6
Insula5.06 ± 0.16
Limbic Lobe5.16 ± 0.34
Mesencephalon5.12 ± 0.37
Myelencephalon5.15 ± 0.37
Occipital Lobe5.23 ± 0.3
Parietal Lobe5.14 ± 0.4
Pontine Tegmentum5.11 ± 0.43
Striatum5.28 ± 0.31
Subthalamus5.1 ± 0.18
Temporal Lobe5.17 ± 0.3
Thalamus5.13 ± 0.4
White Matter6.12 ± 0.16
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
NfyaCBCerebellum1.67
1.85
NfyaCTXCerebral cortex0.71
0.7
NfyaHIPHippocampal region0.64
1
NfyaHPFHippocampal formation0.53
0.8
NfyaHYHypothalamus0.14
0.27
NfyaLSXLateral septal complex0.07
0.05
NfyaMBMidbrain0.35
0.87
NfyaMYMedulla0.51
0.76
NfyaOLFOlfactory bulb0.64
0.7
NfyaPPons0.26
0.42
NfyaPALPallidum0.08
0.09
NfyaRHPRetrohippocampal region0.35
0.53
NfyasAMYStriatum-like amygdalar nuclei0.04
0
NfyaSTRStriatum0.31
0.24
NfyaSTRdStriatum dorsal region0.44
0.32
NfyaSTRvStriatum ventral region0.15
0.15
NfyaTHThalamus0.29
0.29
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
NFYA_HUMAN_323 23 323 345 EKDSPHMQDPNQADEEAMTQIIR PRIDE
PAp00070791 19 223 241 IPLPGAEMLEEEPLYVNAK Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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