Annotation Detail for NHS
Basic Information Top
| Gene Symbol: | NHS ( DKFZp781F2016,DKFZp781L0254,FLJ22511,SCML1 ) |
|---|---|
| Gene Full Name: | Nance-Horan syndrome (congenital cataracts and dental anomalies) |
| Band: | Xp22.2-p22.13 |
| Quick Links | Entrez ID:4810; OMIM: 300457; Uniprot ID:NHS_HUMAN; ENSEMBL ID: ENSG00000188158; HGNC ID: 7820 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.201623
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 0 / 70761 | 0 | |
| blastocyst | 0 / 62319 | 0 | |
| fetus | 9 / 564012 | 15 |  |
| neonate | 0 / 31097 | 0 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 0 / 55556 | 0 | |
| adult | 16 / 1939121 | 8 |  |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 0 / 94178 | 0 | |
| cervical tumor | 0 / 34366 | 0 | |
| chondrosarcoma | 2 / 82823 | 24 | |
| colorectal tumor | 2 / 114246 | 17 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 5 / 119369 | 41 | |
| germ cell tumor | 6 / 263845 | 22 | |
| glioma | 0 / 106883 | 0 | |
| head and neck tumor | 0 / 136302 | 0 | |
| kidney tumor | 0 / 68959 | 0 | |
| leukemia | 0 / 95842 | 0 | |
| liver tumor | 0 / 96359 | 0 | |
| lung tumor | 0 / 103127 | 0 | |
| lymphoma | 0 / 71755 | 0 | |
| non-neoplasia | 1 / 97250 | 10 | |
| normal | 38 / 3360307 | 11 | |
| ovarian tumor | 0 / 76682 | 0 | |
| pancreatic tumor | 0 / 104616 | 0 | |
| primitive neuroectodermal tumor of the CNS | 0 / 125680 | 0 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 0 / 46356 | 0 | |
| skin tumor | 0 / 124949 | 0 | |
| soft tissue/muscle tissue tumor | 0 / 125191 | 0 | |
| uterine tumor | 0 / 90257 | 0 |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 0 / 40015 | 0 | |
| bladder | 1 / 29757 | 33 | |
| blood | 0 / 123478 | 0 | |
| bone | 0 / 71655 | 0 | |
| bone marrow | 0 / 48801 | 0 | |
| brain | 4 / 1100989 | 3 | |
| cervix | 0 / 48171 | 0 | |
| connective tissue | 2 / 149255 | 13 | |
| ear | 4 / 16212 | 246 |  |
| embryonic tissue | 0 / 215722 | 0 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 9 / 211054 | 42 | |
| heart | 0 / 89626 | 0 | |
| intestine | 2 / 234472 | 8 | |
| kidney | 7 / 211777 | 33 | |
| larynx | 0 / 24145 | 0 | |
| liver | 0 / 207743 | 0 | |
| lung | 7 / 336974 | 20 | |
| lymph | 0 / 44270 | 0 | |
| lymph node | 0 / 91610 | 0 | |
| mammary gland | 0 / 153271 | 0 | |
| mouth | 0 / 67052 | 0 | |
| muscle | 0 / 107715 | 0 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 0 / 102051 | 0 | |
| pancreas | 2 / 214812 | 9 | |
| parathyroid | 0 / 20539 | 0 | |
| pharynx | 0 / 41328 | 0 | |
| pituitary gland | 0 / 16585 | 0 | |
| placenta | 0 / 280825 | 0 | |
| prostate | 1 / 189345 | 5 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 0 / 210574 | 0 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 5 / 96619 | 51 |  |
| testis | 5 / 330442 | 15 | |
| thymus | 0 / 81131 | 0 | |
| thyroid | 0 / 47473 | 0 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 0 / 52413 | 0 | |
| umbilical cord | 0 / 13680 | 0 | |
| uterus | 1 / 232878 | 4 | |
| vascular | 0 / 51780 | 0 |
Microarray in - Probe name: CUST_10100_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 6.99 ± 0.29 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 6.86 ± 0.15 | |
| Basal Part of Pons | 5.55 ± 0.33 | |
| Cerebellar Cortex | 5.55 ± 0.32 | |
| Cerebellar Nuclei | 6.38 ± 0.36 | |
| Claustrum | 6.73 ± 0.52 | |
| Epithalamus | 6.56 ± 0.34 | |
| Frontal Lobe | 6.05 ± 0.54 | |
| Globus Pallidus | 5.56 ± 0.83 | |
| Hypothalamus | 6.48 ± 0.47 | |
| Insula | 6.07 ± 0.37 | |
| Limbic Lobe | 6.04 ± 0.61 | |
| Mesencephalon | 6.11 ± 0.6 | |
| Myelencephalon | 6.16 ± 0.55 | |
| Occipital Lobe | 6.18 ± 0.4 | |
| Parietal Lobe | 6.27 ± 0.61 | |
| Pontine Tegmentum | 6.24 ± 0.6 | |
| Striatum | 6.63 ± 0.36 | |
| Subthalamus | 6.56 ± 0.02 | |
| Temporal Lobe | 6.09 ± 0.51 | |
| Thalamus | 5.66 ± 0.4 | |
| White Matter | 4.09 ± 0.88 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Nhs | CB | Cerebellum | 2.56 | |
| 3.23 | | |||
| Nhs | CTX | Cerebral cortex | 1.54 | |
| 1.29 | | |||
| Nhs | HIP | Hippocampal region | 0.94 | |
| 0.81 | | |||
| Nhs | HPF | Hippocampal formation | 0.96 | |
| 0.8 | | |||
| Nhs | HY | Hypothalamus | 0.73 | |
| 0.57 | | |||
| Nhs | LSX | Lateral septal complex | 2.58 | |
| 1.53 | | |||
| Nhs | MB | Midbrain | 2.64 | |
| 2.42 | | |||
| Nhs | MY | Medulla | 7.4 | |
| 7.7 | | |||
| Nhs | OLF | Olfactory bulb | 4.03 | |
| 3.11 | | |||
| Nhs | P | Pons | 3.77 | |
| 4.05 | | |||
| Nhs | PAL | Pallidum | 2.15 | |
| 1.56 | | |||
| Nhs | RHP | Retrohippocampal region | 1.04 | |
| 0.83 | | |||
| Nhs | sAMY | Striatum-like amygdalar nuclei | 2.11 | |
| 1.51 | | |||
| Nhs | STR | Striatum | 1.09 | |
| 0.73 | | |||
| Nhs | STRd | Striatum dorsal region | 0.61 | |
| 0.44 | | |||
| Nhs | STRv | Striatum ventral region | 0.85 | |
| 0.42 | | |||
| Nhs | TH | Thalamus | 1.5 | |
| 1.33 | |