AutismKB 2.0

Annotation Detail for NME3


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Basic Information Top
Gene Symbol:NME3 ( DR-nm23,KIAA0516,NDPK-C,NDPKC,NM23-H3,NM23H3,c371H6.2 )
Gene Full Name: non-metastatic cells 3, protein expressed in
Band: 16p13.3
Quick LinksEntrez ID:4832; OMIM: 601817; Uniprot ID:NDK3_HUMAN; ENSEMBL ID: ENSG00000103024; HGNC ID: 7851
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body6 / 7076184
blastocyst2 / 6231932
fetus20 / 56401235
neonate0 / 310970 
infant0 / 236200 
juvenile0 / 555560 
adult73 / 193912137
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor3 / 9417831
cervical tumor0 / 343660 
chondrosarcoma3 / 8282336
colorectal tumor7 / 11424661
esophageal tumor0 / 172900 
gastrointestinal tumor7 / 11936958
germ cell tumor1 / 2638453
glioma9 / 10688384
head and neck tumor0 / 1363020 
kidney tumor0 / 689590 
leukemia1 / 9584210
liver tumor1 / 9635910
lung tumor2 / 10312719
lymphoma4 / 7175555
non-neoplasia0 / 972500 
normal118 / 336030735
ovarian tumor2 / 7668226
pancreatic tumor12 / 104616114
primitive neuroectodermal tumor of the CNS12 / 12568095
prostate cancer7 / 10268068
retinoblastoma5 / 46356107
skin tumor2 / 12494916
soft tissue/muscle tissue tumor6 / 12519147
uterine tumor1 / 9025711
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland2 / 3319760
ascites6 / 40015149
bladder0 / 297570 
blood2 / 12347816
bone4 / 7165555
bone marrow0 / 488010 
brain32 / 110098929
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue12 / 21572255
esophagus0 / 202090 
eye20 / 21105494
heart4 / 8962644
intestine10 / 23447242
kidney4 / 21177718
larynx0 / 241450 
liver1 / 2077434
lung12 / 33697435
lymph4 / 4427090
lymph node0 / 916100 
mammary gland3 / 15327119
mouth0 / 670520 
muscle5 / 10771546
nerve1 / 1576863
ovary2 / 10205119
pancreas21 / 21481297
parathyroid2 / 2053997
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta3 / 28082510
prostate13 / 18934568
salivary gland0 / 201550 
skin7 / 21057433
spleen0 / 539520 
stomach5 / 9661951
testis7 / 33044221
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus12 / 23287851
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204862_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts4.35
Adipocyte3.25
AdrenalCortex3.4
Adrenalgland3.55
Amygdala3.55
Appendix3.3
AtrioventricularNode2.4
BDCA4+_DentriticCells9.65
Bonemarrow3.25
BronchialEpithelialCells3.35
CD105+_Endothelial3.35
CD14+_Monocytes10.15
CD19+_BCells(neg._sel.)11.9
CD33+_Myeloid5.3
CD34+6.2
CD4+_Tcells24.5
CD56+_NKCells17.25
CD71+_EarlyErythroid3.05
CD8+_Tcells23.35
CardiacMyocytes4.05
Caudatenucleus2.95
Cerebellum2.7
CerebellumPeduncles3.7
CiliaryGanglion2.25
CingulateCortex3.35
Colorectaladenocarcinoma3.35
DorsalRootGanglion2.45
FetalThyroid3.25
Fetalbrain3.35
Fetalliver2.8
Fetallung2.8
GlobusPallidus2.4
Heart18.65
Hypothalamus3.65
Kidney2.6
Leukemia_chronicMyelogenousK-5622.95
Leukemia_promyelocytic-HL-602.9
Leukemialymphoblastic(MOLT-4)2.65
Liver4.25
Lung13.9
Lymphnode2.9
Lymphoma_burkitts(Daudi)4.15
Lymphoma_burkitts(Raji)8.45
MedullaOblongata3
OccipitalLobe3
OlfactoryBulb2.6
Ovary2.15
Pancreas2.65
PancreaticIslet3.5
ParietalLobe3.4
Pituitary3.9
Placenta3.45
Pons3.1
PrefrontalCortex4.55
Prostate25.45
Salivarygland2.6
SkeletalMuscle3.6
Skin2.45
SmoothMuscle3.8
Spinalcord3.55
SubthalamicNucleus2.95
SuperiorCervicalGanglion3.65
TemporalLobe3
Testis2.85
TestisGermCell2.8
TestisIntersitial2.75
TestisLeydigCell3.25
TestisSeminiferousTubule2.85
Thalamus3.35
Thymus2.7
Thyroid9.75
Tongue3.15
Tonsil3.2
Trachea2.75
TrigeminalGanglion3.15
Uterus4.9
UterusCorpus2.9
WholeBlood3.65
Wholebrain8.2
colon3.4
pineal_day22.88
pineal_night22.06
retina6.225
small_intestine3.25
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_16515_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.61 ± 0.74
Basal Forebrain5.44 ± 0.26
Basal Part of Pons5.54 ± 0.42
Cerebellar Cortex5.03 ± 0.59
Cerebellar Nuclei5.48 ± 0.36
Claustrum5.79 ± 0.59
Epithalamus4.84 ± 0.29
Frontal Lobe5.42 ± 0.6
Globus Pallidus5.89 ± 0.4
Hypothalamus5.28 ± 0.54
Insula5.32 ± 0.55
Limbic Lobe5.5 ± 0.58
Mesencephalon5.51 ± 0.42
Myelencephalon5.45 ± 0.58
Occipital Lobe5.34 ± 0.57
Parietal Lobe5.35 ± 0.5
Pontine Tegmentum5.22 ± 0.57
Striatum5.5 ± 0.55
Subthalamus5.23 ± 0.19
Temporal Lobe5.35 ± 0.62
Thalamus5.48 ± 0.44
White Matter5.83 ± 0.58
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Nme3CBCerebellum22.43
26.11
Nme3CTXCerebral cortex49.57
35.79
Nme3HIPHippocampal region44.37
56.75
Nme3HPFHippocampal formation47.65
50.81
Nme3HYHypothalamus42.84
33.88
Nme3LSXLateral septal complex25.84
18.1
Nme3MBMidbrain21.45
18.59
Nme3MYMedulla28.83
30.17
Nme3OLFOlfactory bulb68.28
52.85
Nme3PPons28.09
28.82
Nme3PALPallidum34.1
29.3
Nme3RHPRetrohippocampal region55.92
42.64
Nme3sAMYStriatum-like amygdalar nuclei62.53
46.53
Nme3STRStriatum37.89
27.81
Nme3STRdStriatum dorsal region29.72
21.68
Nme3STRvStriatum ventral region55.12
38.9
Nme3THThalamus21.45
16.46
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00159482 12 24 35 TFLAVKPDGVQR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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