Annotation Detail for CNOT4
Basic Information Top
| Gene Symbol: | CNOT4 ( CLONE243,NOT4,NOT4H ) |
|---|---|
| Gene Full Name: | CCR4-NOT transcription complex, subunit 4 |
| Band: | 7q33 |
| Quick Links | Entrez ID:4850; OMIM: 604911; Uniprot ID:CNOT4_HUMAN; ENSEMBL ID: ENSG00000080802; HGNC ID: 7880 |
| Relate to Another Database: | SFARIGene; denovo-db |
- Unigene ID: Hs.490224
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
 | |||
| embryoid body | 2 / 70761 | 28 |  |
| blastocyst | 1 / 62319 | 16 | |
| fetus | 46 / 564012 | 81 |  |
| neonate | 1 / 31097 | 32 | |
| infant | 0 / 23620 | 0 | |
| juvenile | 1 / 55556 | 17 | |
| adult | 59 / 1939121 | 30 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adrenal tumor | 0 / 12794 | 0 | |
| bladder carcinoma | 0 / 17475 | 0 | |
| breast (mammary gland) tumor | 3 / 94178 | 31 | |
| cervical tumor | 2 / 34366 | 58 | |
| chondrosarcoma | 0 / 82823 | 0 | |
| colorectal tumor | 0 / 114246 | 0 | |
| esophageal tumor | 0 / 17290 | 0 | |
| gastrointestinal tumor | 4 / 119369 | 33 | |
| germ cell tumor | 20 / 263845 | 75 | |
| glioma | 11 / 106883 | 102 | |
| head and neck tumor | 7 / 136302 | 51 | |
| kidney tumor | 2 / 68959 | 29 | |
| leukemia | 6 / 95842 | 62 | |
| liver tumor | 1 / 96359 | 10 |  |
| lung tumor | 1 / 103127 | 9 | |
| lymphoma | 2 / 71755 | 27 | |
| non-neoplasia | 3 / 97250 | 30 | |
| normal | 154 / 3360307 | 45 | |
| ovarian tumor | 1 / 76682 | 13 | |
| pancreatic tumor | 5 / 104616 | 47 | |
| primitive neuroectodermal tumor of the CNS | 5 / 125680 | 39 | |
| prostate cancer | 0 / 102680 | 0 | |
| retinoblastoma | 1 / 46356 | 21 | |
| skin tumor | 3 / 124949 | 24 | |
| soft tissue/muscle tissue tumor | 7 / 125191 | 55 | |
| uterine tumor | 2 / 90257 | 22 | |
| Pool Name | Gene EST/Total EST in pool | Transcripts per million(TPM) | Bar based on TPM |
|---|---|---|---|
| |||
| adipose tissue | 0 / 13106 | 0 | |
| adrenal gland | 0 / 33197 | 0 | |
| ascites | 2 / 40015 | 49 | |
| bladder | 3 / 29757 | 100 | |
| blood | 6 / 123478 | 48 | |
| bone | 2 / 71655 | 27 | |
| bone marrow | 3 / 48801 | 61 | |
| brain | 80 / 1100989 | 72 | |
| cervix | 2 / 48171 | 41 | |
| connective tissue | 6 / 149255 | 40 | |
| ear | 0 / 16212 | 0 | |
| embryonic tissue | 8 / 215722 | 37 | |
| esophagus | 0 / 20209 | 0 | |
| eye | 8 / 211054 | 37 | |
| heart | 3 / 89626 | 33 | |
| intestine | 2 / 234472 | 8 | |
| kidney | 10 / 211777 | 47 | |
| larynx | 2 / 24145 | 82 | |
| liver | 2 / 207743 | 9 | |
| lung | 15 / 336974 | 44 | |
| lymph | 1 / 44270 | 22 | |
| lymph node | 9 / 91610 | 98 | |
| mammary gland | 7 / 153271 | 45 | |
| mouth | 2 / 67052 | 29 | |
| muscle | 3 / 107715 | 27 | |
| nerve | 0 / 15768 | 0 | |
| ovary | 2 / 102051 | 19 | |
| pancreas | 7 / 214812 | 32 | |
| parathyroid | 3 / 20539 | 146 | |
| pharynx | 2 / 41328 | 48 | |
| pituitary gland | 1 / 16585 | 60 | |
| placenta | 5 / 280825 | 17 | |
| prostate | 2 / 189345 | 10 | |
| salivary gland | 0 / 20155 | 0 | |
| skin | 8 / 210574 | 37 | |
| spleen | 0 / 53952 | 0 | |
| stomach | 3 / 96619 | 31 | |
| testis | 26 / 330442 | 78 | |
| thymus | 3 / 81131 | 36 | |
| thyroid | 1 / 47473 | 21 | |
| tonsil | 0 / 16999 | 0 | |
| trachea | 3 / 52413 | 57 | |
| umbilical cord | 1 / 13680 | 73 | |
| uterus | 5 / 232878 | 21 | |
| vascular | 2 / 51780 | 38 | |
- Microarray Platform: GeneAtlas U133A, gcrma
- Affymatrix Probe ID: 210866_s_at
| Cell line | Expression level | Expression bar |
|---|---|---|
| ||
| 721_B_lymphoblasts | 6.65 | |
| Adipocyte | 5.55 | |
| AdrenalCortex | 6.9 | |
| Adrenalgland | 5.1 | |
| Amygdala | 6.15 | |
| Appendix | 6.6 | |
| AtrioventricularNode | 5.4 | |
| BDCA4+_DentriticCells | 5.45 | |
| Bonemarrow | 5.9 | |
| BronchialEpithelialCells | 5.8 | |
| CD105+_Endothelial | 5.7 | |
| CD14+_Monocytes | 6.25 | |
| CD19+_BCells(neg._sel.) | 6 | |
| CD33+_Myeloid | 7.3 | |
| CD34+ | 7 | |
| CD4+_Tcells | 6 | |
| CD56+_NKCells | 6.85 | |
| CD71+_EarlyErythroid | 5.4 | |
| CD8+_Tcells | 5.45 | |
| CardiacMyocytes | 7.9 | |
| Caudatenucleus | 5.3 | |
| Cerebellum | 4.8 | |
| CerebellumPeduncles | 6.9 | |
| CiliaryGanglion | 4.3 | |
| CingulateCortex | 6.05 | |
| Colorectaladenocarcinoma | 5.75 | |
| DorsalRootGanglion | 5.2 | |
| FetalThyroid | 5.75 | |
| Fetalbrain | 5.85 | |
| Fetalliver | 5.2 | |
| Fetallung | 4.75 | |
| GlobusPallidus | 4.25 | |
| Heart | 8 | |
| Hypothalamus | 6.25 | |
| Kidney | 5.05 | |
| Leukemia_chronicMyelogenousK-562 | 5.3 | |
| Leukemia_promyelocytic-HL-60 | 5.2 | |
| Leukemialymphoblastic(MOLT-4) | 4.75 | |
| Liver | 8.1 | |
| Lung | 6.5 | |
| Lymphnode | 5.1 | |
| Lymphoma_burkitts(Daudi) | 7.75 | |
| Lymphoma_burkitts(Raji) | 8.4 | |
| MedullaOblongata | 5.9 | |
| OccipitalLobe | 5.15 | |
| OlfactoryBulb | 4.65 | |
| Ovary | 4 | |
| Pancreas | 4.95 | |
| PancreaticIslet | 6.4 | |
| ParietalLobe | 6.8 | |
| Pituitary | 6.9 | |
| Placenta | 6.1 | |
| Pons | 6.2 | |
| PrefrontalCortex | 6.8 | |
| Prostate | 6.75 | |
| Salivarygland | 4.8 | |
| SkeletalMuscle | 13.9 | |
| Skin | 5.35 | |
| SmoothMuscle | 6.75 | |
| Spinalcord | 6.3 | |
| SubthalamicNucleus | 5.3 | |
| SuperiorCervicalGanglion | 8 | |
| TemporalLobe | 5.35 | |
| Testis | 5.35 | |
| TestisGermCell | 4.75 | |
| TestisIntersitial | 5.05 | |
| TestisLeydigCell | 6 | |
| TestisSeminiferousTubule | 5.05 | |
| Thalamus | 5.9 | |
| Thymus | 4.7 | |
| Thyroid | 7.05 | |
| Tongue | 6.25 | |
| Tonsil | 5.75 | |
| Trachea | 4.9 | |
| TrigeminalGanglion | 6.25 | |
| Uterus | 4.75 | |
| UterusCorpus | 5.9 | |
| WholeBlood | 6.2 | |
| Wholebrain | 4.95 | |
| colon | 5.85 | |
| pineal_day | 7.06 | |
| pineal_night | 7.04 | |
| retina | 6.95 | |
| small_intestine | 5.65 | |
- Probe name: CUST_1656_PI416261804
- Donor H0351.2001
- Sex: Male Age: 24 years Race/Ethnicity: African American Handedness: Left
- Tissue Receipt Date: 7/29/2009 Serology: Pass Tissue pH :6.72 Additional Medical Information :History of asthma
- Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
- Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
| Tissue | Expression(mean ± stddev) | Expression Bar |
|---|---|---|
| Amygdala | 5.11 ± 0.47 | ![](../"images/bar_3.png"){kind=small}   |
| Basal Forebrain | 4.96 ± 0.32 | |
| Basal Part of Pons | 4.75 ± 0.42 | |
| Cerebellar Cortex | 5.11 ± 0.34 | |
| Cerebellar Nuclei | 4.68 ± 0.43 | |
| Claustrum | 5.31 ± 0.69 | |
| Epithalamus | 4.73 ± 0.26 | |
| Frontal Lobe | 4.66 ± 0.48 | |
| Globus Pallidus | 5.05 ± 0.42 | |
| Hypothalamus | 4.45 ± 0.4 | |
| Insula | 4.84 ± 0.5 | |
| Limbic Lobe | 5.01 ± 0.44 | |
| Mesencephalon | 4.91 ± 0.48 | |
| Myelencephalon | 4.8 ± 0.55 | |
| Occipital Lobe | 5.07 ± 0.7 | |
| Parietal Lobe | 4.92 ± 0.44 | |
| Pontine Tegmentum | 4.89 ± 0.57 | |
| Striatum | 4.77 ± 0.51 | |
| Subthalamus | 4.52 ± 0.2 | |
| Temporal Lobe | 4.82 ± 0.5 | |
| Thalamus | 4.81 ± 0.57 | |
| White Matter | 4.59 ± 0.5 | |
Mouse Brain ISH 
| Gene Symbol | Brain Structure ID | Brain Structure Name | Express Desity/Level (Meatured by ISH) | Express Bar |
|---|---|---|---|---|
| Cnot4 | CB | Cerebellum | 70.96 | |
| 96.74 | | |||
| Cnot4 | CTX | Cerebral cortex | 74.32 | |
| 59.46 | | |||
| Cnot4 | HIP | Hippocampal region | 53.23 | |
| 72.26 | | |||
| Cnot4 | HPF | Hippocampal formation | 62.65 | |
| 70.24 | | |||
| Cnot4 | HY | Hypothalamus | 36.43 | |
| 29.79 | | |||
| Cnot4 | LSX | Lateral septal complex | 23.38 | |
| 19.21 | | |||
| Cnot4 | MB | Midbrain | 31.68 | |
| 30.29 | | |||
| Cnot4 | MY | Medulla | 41.22 | |
| 47.49 | | |||
| Cnot4 | OLF | Olfactory bulb | 88.78 | |
| 83.75 | | |||
| Cnot4 | P | Pons | 37.62 | |
| 43.53 | | |||
| Cnot4 | PAL | Pallidum | 23.75 | |
| 21.75 | | |||
| Cnot4 | RHP | Retrohippocampal region | 84.7 | |
| 71.5 | | |||
| Cnot4 | sAMY | Striatum-like amygdalar nuclei | 43.36 | |
| 33.49 | | |||
| Cnot4 | STR | Striatum | 33 | |
| 25.2 | | |||
| Cnot4 | STRd | Striatum dorsal region | 29.81 | |
| 22.53 | | |||
| Cnot4 | STRv | Striatum ventral region | 40.18 | |
| 30.25 | | |||
| Cnot4 | TH | Thalamus | 34.64 | |
| 29.52 | |
| Peptide Name | Peptide Lengh | Peptide Start | Peptide End | Peptide Sequence | Source |
|---|---|---|---|---|---|
| PAp00072025 | 20 | 58 | 77 | KPYPEDPAVYKPLSQEELQR | Peptide Atlas |