AutismKB 2.0

Annotation Detail for NOV


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:NOV ( CCN3,IGFBP9 )
Gene Full Name: nephroblastoma overexpressed gene
Band: 8q24.12
Quick LinksEntrez ID:4856; OMIM: 164958; Uniprot ID:NOV_HUMAN; ENSEMBL ID: ENSG00000136999; HGNC ID: 7885
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus29 / 56401251
neonate1 / 3109732
infant0 / 236200 
juvenile1 / 5555617
adult50 / 193912125
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor12 / 12794937
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor2 / 3436658
chondrosarcoma9 / 82823108
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor6 / 11936950
germ cell tumor3 / 26384511
glioma4 / 10688337
head and neck tumor2 / 13630214
kidney tumor1 / 6895914
leukemia1 / 9584210
liver tumor5 / 9635951
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal149 / 336030744
ovarian tumor3 / 7668239
pancreatic tumor1 / 1046169
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer1 / 1026809
retinoblastoma0 / 463560 
skin tumor4 / 12494932
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor4 / 9025744
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland51 / 331971536
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone5 / 7165569
bone marrow0 / 488010 
brain69 / 110098962
cervix7 / 48171145
connective tissue5 / 14925533
ear15 / 16212925
embryonic tissue0 / 2157220 
esophagus0 / 202090 
eye1 / 2110544
heart1 / 8962611
intestine1 / 2344724
kidney4 / 21177718
larynx0 / 241450 
liver5 / 20774324
lung3 / 3369748
lymph0 / 442700 
lymph node0 / 916100 
mammary gland2 / 15327113
mouth2 / 6705229
muscle2 / 10771518
nerve1 / 1576863
ovary2 / 10205119
pancreas2 / 2148129
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta0 / 2808250 
prostate2 / 18934510
salivary gland0 / 201550 
skin7 / 21057433
spleen0 / 539520 
stomach6 / 9661962
testis1 / 3304423
thymus0 / 811310 
thyroid1 / 4747321
tonsil0 / 169990 
trachea1 / 5241319
umbilical cord0 / 136800 
uterus5 / 23287821
vascular16 / 51780308
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 204501_at
Cell line Expression level Expression bar
721_B_lymphoblasts6.65
Adipocyte5.85
AdrenalCortex303.8
Adrenalgland389.9
Amygdala8.7
Appendix6.25
AtrioventricularNode5.45
BDCA4+_DentriticCells5.75
Bonemarrow6.45
BronchialEpithelialCells5.7
CD105+_Endothelial5.7
CD14+_Monocytes6.2
CD19+_BCells(neg._sel.)5.95
CD33+_Myeloid7.3
CD34+6.95
CD4+_Tcells6.05
CD56+_NKCells6.45
CD71+_EarlyErythroid5.4
CD8+_Tcells5.4
CardiacMyocytes8.2
Caudatenucleus5.3
Cerebellum5.75
CerebellumPeduncles7.15
CiliaryGanglion37.35
CingulateCortex6.15
Colorectaladenocarcinoma5.8
DorsalRootGanglion43.55
FetalThyroid5.75
Fetalbrain5.95
Fetalliver5.65
Fetallung4.75
GlobusPallidus6.8
Heart8.85
Hypothalamus6.3
Kidney5.5
Leukemia_chronicMyelogenousK-5625.2
Leukemia_promyelocytic-HL-605.2
Leukemialymphoblastic(MOLT-4)4.45
Liver9.05
Lung6.7
Lymphnode5.05
Lymphoma_burkitts(Daudi)7.7
Lymphoma_burkitts(Raji)8.55
MedullaOblongata5.25
OccipitalLobe6.35
OlfactoryBulb5
Ovary4.45
Pancreas4.75
PancreaticIslet6.3
ParietalLobe7.05
Pituitary10.25
Placenta6
Pons6.5
PrefrontalCortex7.1
Prostate6.6
Salivarygland4.65
SkeletalMuscle7.1
Skin6.5
SmoothMuscle6.55
Spinalcord8.3
SubthalamicNucleus5.95
SuperiorCervicalGanglion84.75
TemporalLobe5.5
Testis5
TestisGermCell4.85
TestisIntersitial4.9
TestisLeydigCell6
TestisSeminiferousTubule5.05
Thalamus6.1
Thymus4.55
Thyroid8.2
Tongue6.55
Tonsil5.65
Trachea5.45
TrigeminalGanglion6.95
Uterus4.7
UterusCorpus7.6
WholeBlood6.35
Wholebrain7.45
colon5.75
pineal_day7.06
pineal_night7.02
retina6.925
small_intestine5.5
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_471_PI416408490
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala5.51 ± 0.79
Basal Forebrain4.53 ± 0.11
Basal Part of Pons4.68 ± 0.79
Cerebellar Cortex4.9 ± 0.57
Cerebellar Nuclei5 ± 0.49
Claustrum5.52 ± 0.64
Epithalamus5.43 ± 0.59
Frontal Lobe5.67 ± 0.62
Globus Pallidus3.54 ± 0.97
Hypothalamus5.6 ± 0.88
Insula5.85 ± 0.3
Limbic Lobe6.31 ± 0.88
Mesencephalon5.52 ± 0.82
Myelencephalon5.5 ± 0.94
Occipital Lobe4.58 ± 1.07
Parietal Lobe5.45 ± 0.87
Pontine Tegmentum5.36 ± 0.65
Striatum4.54 ± 1.22
Subthalamus6.96 ± 0.73
Temporal Lobe5.91 ± 0.56
Thalamus4.81 ± 0.62
White Matter3.66 ± 0.44
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
NovCBCerebellum11.91
16.21
NovCTXCerebral cortex99.74
100
NovHIPHippocampal region62.26
99.48
NovHPFHippocampal formation86.1
100
NovHYHypothalamus14.01
10.89
NovLSXLateral septal complex10.69
11.26
NovMBMidbrain11.4
9.99
NovMYMedulla15.75
14.72
NovOLFOlfactory bulb82.64
100
NovPPons15.01
14.42
NovPALPallidum11.37
8.81
NovRHPRetrohippocampal region100
100
NovsAMYStriatum-like amygdalar nuclei32.34
31.73
NovSTRStriatum16.17
15.76
NovSTRdStriatum dorsal region14.63
14.75
NovSTRvStriatum ventral region14.07
10.76
NovTHThalamus9.45
6.26
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00377073 14 56 69 AVLDGCSCCLVCAR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved