AutismKB 2.0

Annotation Detail for NOVA1


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Basic Information Top
Gene Symbol:NOVA1 ( Nova-1 )
Gene Full Name: neuro-oncological ventral antigen 1
Band: 14q12
Quick LinksEntrez ID:4857; OMIM: 602157; Uniprot ID:NOVA1_HUMAN; ENSEMBL ID: ENSG00000139910; HGNC ID: 7886
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body1 / 7076114
blastocyst0 / 623190 
fetus22 / 56401239
neonate0 / 310970 
infant1 / 2362042
juvenile0 / 555560 
adult37 / 193912119
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor17 / 94178180
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor0 / 1142460 
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor7 / 26384526
glioma15 / 106883140
head and neck tumor3 / 13630222
kidney tumor1 / 6895914
leukemia0 / 958420 
liver tumor0 / 963590 
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia2 / 9725020
normal89 / 336030726
ovarian tumor1 / 7668213
pancreatic tumor0 / 1046160 
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor0 / 1251910 
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue1 / 1310676
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain73 / 110098966
cervix0 / 481710 
connective tissue1 / 1492556
ear2 / 16212123
embryonic tissue5 / 21572223
esophagus0 / 202090 
eye2 / 2110549
heart0 / 896260 
intestine2 / 2344728
kidney1 / 2117774
larynx0 / 241450 
liver0 / 2077430 
lung4 / 33697411
lymph0 / 442700 
lymph node0 / 916100 
mammary gland17 / 153271110
mouth3 / 6705244
muscle1 / 1077159
nerve1 / 1576863
ovary1 / 1020519
pancreas3 / 21481213
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland1 / 1658560
placenta0 / 2808250 
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen1 / 5395218
stomach1 / 9661910
testis4 / 33044212
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205794_s_at
Cell line Expression level Expression bar
721_B_lymphoblasts5.65
Adipocyte4.95
AdrenalCortex5.05
Adrenalgland4.05
Amygdala74.4
Appendix5.2
AtrioventricularNode4.05
BDCA4+_DentriticCells5.05
Bonemarrow4.7
BronchialEpithelialCells4.6
CD105+_Endothelial4.65
CD14+_Monocytes4.9
CD19+_BCells(neg._sel.)4.9
CD33+_Myeloid5.85
CD34+5.8
CD4+_Tcells4.9
CD56+_NKCells5.7
CD71+_EarlyErythroid4.45
CD8+_Tcells4.4
CardiacMyocytes6.15
Caudatenucleus32.15
Cerebellum301.5
CerebellumPeduncles164.7
CiliaryGanglion3.7
CingulateCortex42.05
Colorectaladenocarcinoma4.9
DorsalRootGanglion3.85
FetalThyroid4.75
Fetalbrain64.8
Fetalliver4.2
Fetallung3.95
GlobusPallidus39.05
Heart6.25
Hypothalamus114
Kidney4
Leukemia_chronicMyelogenousK-5624.2
Leukemia_promyelocytic-HL-604.1
Leukemialymphoblastic(MOLT-4)3.95
Liver6.55
Lung5.35
Lymphnode4.4
Lymphoma_burkitts(Daudi)6.15
Lymphoma_burkitts(Raji)6.8
MedullaOblongata68.9
OccipitalLobe108.5
OlfactoryBulb3.95
Ovary3.3
Pancreas3.8
PancreaticIslet5.05
ParietalLobe42.1
Pituitary31.1
Placenta4.9
Pons44.75
PrefrontalCortex113.6
Prostate5.7
Salivarygland3.9
SkeletalMuscle6.15
Skin4.3
SmoothMuscle5.4
Spinalcord32.5
SubthalamicNucleus33.3
SuperiorCervicalGanglion6.4
TemporalLobe33.9
Testis4.3
TestisGermCell4.1
TestisIntersitial4.05
TestisLeydigCell4.9
TestisSeminiferousTubule4.15
Thalamus44.85
Thymus3.85
Thyroid6.3
Tongue4.9
Tonsil4.7
Trachea4.1
TrigeminalGanglion5.5
Uterus15.15
UterusCorpus4.4
WholeBlood5.05
Wholebrain136.3
colon14.95
pineal_day6.38
pineal_night8.72
retina24.375
small_intestine4.75
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: CUST_10340_PI416261804
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala9.43 ± 0.27
Basal Forebrain9.49 ± 0.17
Basal Part of Pons9.05 ± 0.18
Cerebellar Cortex9.73 ± 0.18
Cerebellar Nuclei9.84 ± 0.21
Claustrum9.29 ± 0.26
Epithalamus9.21 ± 0.4
Frontal Lobe9.26 ± 0.38
Globus Pallidus8.99 ± 0.15
Hypothalamus9.44 ± 0.75
Insula9.25 ± 0.31
Limbic Lobe9.21 ± 0.34
Mesencephalon9.43 ± 0.4
Myelencephalon9.3 ± 0.37
Occipital Lobe9.57 ± 0.31
Parietal Lobe9.51 ± 0.29
Pontine Tegmentum9.47 ± 0.3
Striatum9.06 ± 0.27
Subthalamus9.97 ± 0.24
Temporal Lobe9.24 ± 0.31
Thalamus9.15 ± 0.25
White Matter9.55 ± 0.21
Mouse Brain ISH
Peptide Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018