AutismKB 2.0

Annotation Detail for FXYD2


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Basic Information Top
Gene Symbol:FXYD2 ( ATP1G1,HOMG2,MGC12372 )
Gene Full Name: FXYD domain containing ion transport regulator 2
Band: 11q23.3
Quick LinksEntrez ID:486; OMIM: 601814; Uniprot ID:ATNG_HUMAN; ENSEMBL ID: ENSG00000137731; HGNC ID: 4026
Relate to Another Database: SFARIGene; denovo-db
Unigene EST Top
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
embryoid body0 / 707610 
blastocyst0 / 623190 
fetus22 / 56401239
neonate0 / 310970 
infant0 / 236200 
juvenile1 / 5555617
adult36 / 193912118
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adrenal tumor0 / 127940 
bladder carcinoma0 / 174750 
breast (mammary gland) tumor0 / 941780 
cervical tumor0 / 343660 
chondrosarcoma0 / 828230 
colorectal tumor1 / 1142468
esophageal tumor0 / 172900 
gastrointestinal tumor0 / 1193690 
germ cell tumor0 / 2638450 
glioma0 / 1068830 
head and neck tumor0 / 1363020 
kidney tumor19 / 68959275
leukemia3 / 9584231
liver tumor2 / 9635920
lung tumor0 / 1031270 
lymphoma0 / 717550 
non-neoplasia0 / 972500 
normal65 / 336030719
ovarian tumor0 / 766820 
pancreatic tumor4 / 10461638
primitive neuroectodermal tumor of the CNS0 / 1256800 
prostate cancer0 / 1026800 
retinoblastoma0 / 463560 
skin tumor0 / 1249490 
soft tissue/muscle tissue tumor1 / 1251917
uterine tumor0 / 902570 
Pool Name Gene EST/Total EST in pool Transcripts per million(TPM) Bar based on TPM
adipose tissue0 / 131060 
adrenal gland0 / 331970 
ascites0 / 400150 
bladder0 / 297570 
blood1 / 1234788
bone0 / 716550 
bone marrow0 / 488010 
brain5 / 11009894
cervix0 / 481710 
connective tissue1 / 1492556
ear0 / 162120 
embryonic tissue1 / 2157224
esophagus0 / 202090 
eye0 / 2110540 
heart2 / 8962622
intestine1 / 2344724
kidney29 / 211777136
larynx0 / 241450 
liver2 / 2077439
lung1 / 3369742
lymph0 / 442700 
lymph node0 / 916100 
mammary gland0 / 1532710 
mouth0 / 670520 
muscle2 / 10771518
nerve0 / 157680 
ovary0 / 1020510 
pancreas11 / 21481251
parathyroid0 / 205390 
pharynx0 / 413280 
pituitary gland0 / 165850 
placenta0 / 2808250 
prostate1 / 1893455
salivary gland0 / 201550 
skin0 / 2105740 
spleen0 / 539520 
stomach0 / 966190 
testis0 / 3304420 
thymus0 / 811310 
thyroid0 / 474730 
tonsil0 / 169990 
trachea0 / 524130 
umbilical cord0 / 136800 
uterus0 / 2328780 
vascular0 / 517800 
Microarray in BioGPS Top
Select probe  
  • Microarray Platform: GeneAtlas U133A, gcrma
  • Affymatrix Probe ID: 205674_x_at
Cell line Expression level Expression bar
721_B_lymphoblasts7.1
Adipocyte6.7
AdrenalCortex9.1
Adrenalgland5.75
Amygdala6.1
Appendix6.85
AtrioventricularNode5.95
BDCA4+_DentriticCells6
Bonemarrow6.95
BronchialEpithelialCells6.05
CD105+_Endothelial5.85
CD14+_Monocytes5.7
CD19+_BCells(neg._sel.)5.65
CD33+_Myeloid7.35
CD34+7.1
CD4+_Tcells7.4
CD56+_NKCells6
CD71+_EarlyErythroid5.85
CD8+_Tcells6.05
CardiacMyocytes7.65
Caudatenucleus5.6
Cerebellum6.3
CerebellumPeduncles7.35
CiliaryGanglion6.25
CingulateCortex9.35
Colorectaladenocarcinoma6.05
DorsalRootGanglion5.45
FetalThyroid6.1
Fetalbrain6
Fetalliver17.8
Fetallung5.6
GlobusPallidus5.05
Heart8.25
Hypothalamus6.55
Kidney1398.55
Leukemia_chronicMyelogenousK-5625.55
Leukemia_promyelocytic-HL-605.35
Leukemialymphoblastic(MOLT-4)254.1
Liver13.3
Lung6.3
Lymphnode5.15
Lymphoma_burkitts(Daudi)7.9
Lymphoma_burkitts(Raji)8.4
MedullaOblongata7.95
OccipitalLobe5.6
OlfactoryBulb4.85
Ovary4.55
Pancreas17.7
PancreaticIslet163.4
ParietalLobe9.15
Pituitary7.45
Placenta6
Pons8.55
PrefrontalCortex7.45
Prostate7
Salivarygland21.45
SkeletalMuscle9.5
Skin4.85
SmoothMuscle6.85
Spinalcord6.45
SubthalamicNucleus6.7
SuperiorCervicalGanglion7.3
TemporalLobe9.5
Testis5.55
TestisGermCell5.15
TestisIntersitial6.55
TestisLeydigCell6.7
TestisSeminiferousTubule8.6
Thalamus6.35
Thymus7.95
Thyroid6.9
Tongue10.4
Tonsil6.1
Trachea5.3
TrigeminalGanglion9.65
Uterus5.3
UterusCorpus8.9
WholeBlood6.2
Wholebrain4.95
colon5.9
pineal_day7.54
pineal_night7.3
retina8.075
small_intestine5.55
Allen Brain Atlas Top
Human Whole Brain Microarrayview in Allen Brain Atlas
  • Probe id     Donor id      
  • Probe name: A_23_P161769
  • Donor H0351.2001
  • Sex: Male     Age: 24 years     Race/Ethnicity: African American     Handedness: Left
  • Tissue Receipt Date: 7/29/2009     Serology: Pass      Tissue pH :6.72     Additional Medical Information :History of asthma
  • Postmortem Interval: 23 hours (estimated time of death to time that tissue is frozen)
  • Toxicology: Positive for atropine and caffeine, at levels usually not toxicologically significant
Tissue Expression(mean ± stddev) Expression Bar
Amygdala4.15 ± 0.49
Basal Forebrain3.79 ± 0.32
Basal Part of Pons3.82 ± 0.54
Cerebellar Cortex3.88 ± 0.51
Cerebellar Nuclei3.76 ± 0.61
Claustrum4.02 ± 0.72
Epithalamus3.47 ± 0.18
Frontal Lobe3.74 ± 0.53
Globus Pallidus3.65 ± 0.68
Hypothalamus3.85 ± 0.61
Insula3.77 ± 0.28
Limbic Lobe3.85 ± 0.55
Mesencephalon3.82 ± 0.64
Myelencephalon3.86 ± 0.57
Occipital Lobe3.7 ± 0.76
Parietal Lobe3.84 ± 0.63
Pontine Tegmentum3.6 ± 0.57
Striatum3.3 ± 0.64
Subthalamus3.65 ± 0.54
Temporal Lobe3.88 ± 0.45
Thalamus3.71 ± 0.65
White Matter3.42 ± 0.63
Mouse Brain ISH
Gene Symbol Brain Structure ID Brain Structure Name Express Desity/Level (Meatured by ISH) Express Bar
Fxyd2CBCerebellum25.58
34.5
Fxyd2CTXCerebral cortex24.27
16.07
Fxyd2HIPHippocampal region16.32
16.17
Fxyd2HPFHippocampal formation24.35
21.33
Fxyd2HYHypothalamus4.29
5.03
Fxyd2LSXLateral septal complex2.67
3.53
Fxyd2MBMidbrain2.35
3.32
Fxyd2MYMedulla8.14
9.77
Fxyd2OLFOlfactory bulb36.7
29.38
Fxyd2PPons5.49
11.7
Fxyd2PALPallidum10.67
8.29
Fxyd2RHPRetrohippocampal region43.58
31.9
Fxyd2sAMYStriatum-like amygdalar nuclei29.31
18.88
Fxyd2STRStriatum19.06
13.19
Fxyd2STRdStriatum dorsal region18.3
12.4
Fxyd2STRvStriatum ventral region24.88
17.29
Fxyd2THThalamus6.32
5.08
Peptide Top
Peptide Name Peptide Lengh Peptide Start Peptide End Peptide Sequence Source
PAp00803555 14 12 25 GDVDPFYYDYETVR Peptide Atlas

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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